Blood Pressure Forums

Can Metoprolol become less effective at reducing heart rate over time? I've been taking it for about 2 years now. About 6 months ago my heart rate returned to its prior levels (high 50s for resting and low 60's for walking, etc). Nothing bad, but it was a curious step function in the charts. When the drug was working, it had reduced those levels by about 10 beats/minute. My cardiologist doesn't know of any reason why this should happen, so I'm checking to see if others have seen this.. I started to take a GLP-1 (ZEPBOUND) around the same time and wonder if that could be related. ## Metoprolol doesn't usually "wear off" the way some medicines do, but people can see changes in how it affects their heart rate over time. Sometimes your body just adapts a bit, or ...

2 REPLIES

When I should use pot cl and what are the benefits? ## Hi, Abdo! This is just a potassium supplement, it is vital to our overall health and a deficiency in it can cause quite a few health issues, such as high blood pressure, elevated heart rate and irregular heart rhythm. However, you shouldn't take it, unless your doctor has actually done a blood test and told you that you need to take it, because too much of it can also be very dangerous. Did your doctor prescribe this for you? ## I was prescribed pot cl micro 10 meg along with water pill. Now that I'm not taking the water pill I've been still taking the potassium since August. What danger am in. I feel something going on ## Can I crush these very large tablets? ## What happens if I don’t get enough potassium?

4 REPLIES

I am taking Clonidine for an off label use to treat Bruxism(teeth clenching at night). Currently 0.2mg just at night ,but considering trying 0.3mg. My questions are 1) I've heard some people develop a tolerance to Clonidine after taking it for a longtime(so it becomes ineffective and the dose must be increased or treatment stopped). How long can I take before I should take a break ,so I don;t develop this tolerance? 2) If I take 0.3mg and then want to stop taking it , if i reduce my dose by 0.05(half a tablet) every 3-4 days should that avoid rebound hypertension ? My doctor said withdrawal and tolerance are not problems at all so i can stop cold when i want, but don;t think it is a drug she has experience prescribing (only prescribed it as I suggested trying it ,from studies I had ...

4 REPLIES

I was taking 10MG of Lisinopril one time per day. I ended up with a cough. My doctor changed it to 25 MG of Losartan and now my blood pressure has gone back up. Are my new dozes equal to or less than my previous dosage. I do not understand the conversion of MG from drug to drug. ## Hello, Mike! How are you? How long ago did you make the switch? There may be a slight rebound effect from stopping the Lisinopril and starting the new one waiting for it to reach its full level of efficacy. Or it could be that the Losartan doesn't work for you and you may need to switch to something else. The FDA lists the typical side effects of Losartan as possibly including nausea, dizziness, headache, increased urination and hypotension. How high are your current readings? ## Hi, thanks for asking, I ...

3 REPLIES

I take Carvedilol which states that the mfg. is "ZYDU". What is the correct name of this manufacturer and where are they located? ## Zydus Pharmaceuticals Their U.S. headquarters is in Pennington, New Jersey, but they do also have facilities in India. However, regardless of where a medication is manufactured, if it is available to be prescribed in the U.S., then it has met the same strict FDA manufacturing, safety, and efficacy standards as all other prescription medications. Carvedilol may cause side effects, such as nausea, dizziness, headache, increased urination, and hypotension. Ref: Carvedilol Information Is there anything else I can help with? ## Can I take it with propanidol?

2 REPLIES

White oval pill with rph on one side and 121 on the other. This is a Canadian drug - I don't know if things are different in the US. ## Some are different, some aren't, so it can vary. This tablet in particular contains 300mgs of Ratio-Irbesartan, which is most commonly used to treat high blood pressure, and certain cardiac conditions. Ratio-Irbesartan details and description can be found here. Its typical side effects may include nausea, dizziness, headache, increased urination, and hypotension. Is there anything else I can help with? ## What is the proper awy to stop using Irbesartan 121?

2 REPLIES

My wife is 75 years - her blood pressure reads 211/97 with Pulse B&M of 60. What effect will Bilocor (Bisoprolol) 5 tablets have on the above pressure counts? She is using Amlodipine 5 tablets - 1 per day.

I need to know the inactive ingredients because I'm allergic to talc. I had a reaction which is low blood pressure, dizziness, irregular heartbeat, and feeling very tired. Unable to walk. On a patient with heart failure. The did well with the aid of another water pill. ## The inactive ingredients for Zaroxolyn 2.5 mg are listed as: - Magnesium Stearate - Microcrystalline Cellulose - D&C Red No. 33 NDC: 53014-975 What you've reported sounds like some of the possible side effects of this drug according to DailyMed: dizziness/lightheadedness, drowsiness, fatigue, weakness. And just to confirm - you are taking the brand name and not a generic form, right?

1 REPLY

What is not allowed while taking lisinopril; food, drugs or drinks. ## Lisinopril is an ACE inhibitor, that is most commonly used to treat high blood pressure. If you are being treated for high blood pressure, you should be informed to avoid food or beverage products that contain real licorice or licorice extract, since it can raise blood pressure. The only food/beverage interaction is that you should watch out for items that contain very high levels of potassium. Getting to much potassium, while taking Lisinopril can lead to Hyperkalemia, which can be a dangerous condition. Common side effects may include: nausea, drowsiness, headache and stomach pain. Read more: Are there any other comments or questions? ## i have been taking lisinopril-hctz for a month and i have had a bad cough, I j...

80 REPLIES

How long does hydralazine last in your system? ## Hello, Kd! How are you? Hydralazine is classified as a vasodilator that is most commonly used to treat high blood pressure and congestive heart failure. Its typical side effects may possibly include nausea, dizziness, increased urination, headache and hypotension. It's generally life span is anywhere from 10 to 48 hours. Did you suffer adverse effects from it? ## I took this med and experienced redness in my face. Do not use this medicine. It should be banned. I took it for three years. It almost shut my system down. How long does it take to get out of my system? ## Spirinoloctone and endenoprone. Terrible drugs. Spiro i gained 20 lbs most in breasts and butt and kegsn endeniprone potassium sky rocket and went to hospital my blood pr...

11 REPLIES

I've been taking lisinopril, lupin 20 mg. for a number of years My last rx was refilled recently and the pharmacy substituted it with actavis 20 mg. With the lupin, my b.p. readings were always good. With the actavis my b.p.is elavated. I have also experienced a terrible rash and intermittent hives. Could the change in meds have caused this? Yesterday I was prescribed verapamil. (haven't started to take it yet). The pharmacy has filled the prescription with verapamil-ER 120 mg MYLAN. I have severe chemical allergies (paraphenadiamine, Balsam of Peru, methylcloroisothiolizone, quinoline mix and wool alchohols). My outbreak may not have anything to do with the med change, but I thought I should investigate all avenues. ## Actavis is the manufacture and I don't take lisinopril ...

3 REPLIES

My pharmacy has filled my lisinopril prescription with drug from Wockhardt the first month, Acta (Actavis?) the second month, and now Lupin! Lupin is located in Mumbai. Is their GMP as strict as in the US? Do I really want to continue taking lisinopril made in India? What is all this switching generics doing to my body? should I get a new pharmacy where they fill it consistently with drug from the same company? ## You are in no danger from them regularly switching manufacturers, no harm will come of it. Learn more Lisinopril details here. And the one manufactured by Lupin is made to the same strict standards as all others that are available in the U.S. Otherwise, they wouldn't be available here from your pharmacy. And no pharmacy will always fill your prescription with generics from...

4 REPLIES

I am a 64-year old male and I am 6'0 184 pounds. My average blood pressure before i got on Lisinopril 10mg had crept up to "low 140s" over low to mid 80's. Over the last few years the systolic number rose from lower to upper 120's to consistently in the 140's. I started taking 10mg Lisinopril on April 22, 2025 and my blood pressure actually averages right around 122 / 76, so no complaints for my average. I have taken readings every morning since April 22 so, all of MAY, JUNE and JULY and now a few days in August. HOWEVER, I have a number of readings between 99 and 110, many, many more between 110 and 120. Likewise I have many readings between 120 - 130 and a handful of numbers in the 130's. My diastolic numbers have mostly been in the 70's but more freque...

Over the last few months my hair has gotten very thin, brittle, and I’m shedding a LOT. My doctor said it was probably hormones and my age (45 yo female). I started taking Biotin and special shampoos, but they didn’t help. Recently I started digging into the Lisinopril side effects and hair loss is cited. I told my doctor and she told me to discontinue. Has anyone had hair loss on this med, then regrowth after discontinuation? ## Dear WH, Sorry to hear about your hair loss. Based on my own investigation, hair loss isn't "officially" listed by the manufacturer or drug labeller as a side effect of Lisinopril. However, there are numerous mentions of this occurring in patient reviews, so I would consider its consumers to be a worthy citation in my book. I suppose it...

3 REPLIES

My lisinopril (90 day supply, just opened) will expire in 1.5 months. Can I finish it off or do I have to destroy it at the end of January? ## Hello, Lynne! How are you? This medication does not become dangerous once expired, but it may start to lose effectiveness. Thus, in reality, disposing of it, once it expires would be the best thing to do, however, you may want to ask your doctor and pharmacist if you can still finish it, since its loss of effectiveness will most likely be minimal by then. The FDA lists its typical side effects as possibly including nausea, dizziness, headache, increased urination, and hypotension. Is there anything else I can help with? ## How long after the expiration date of lisinopril can you still take it? ## That’s bull about disposing it on the expera...

7 REPLIES

I had taken losartan50/hctz 12.5 for 10 years, In recently years I suffered dry coughing and bad running nose allergy. I found out this is the side effect of losartan. Cutting the dose to half, changing to a water pill.. did not solve the problem. Over this holiday I developed bronchitis and was quite ill. I had very bad coughing, losing voice, sinus infection, nose bleeding, etc. I stopped taking Losartan to avoid further complications. I notified my doctor that I will check my blood pressure if the record is not over 140-90. I will keep the Losartan off. What else can I do? ## Hello, Muchin! How are you doing? Have your symptoms improved, yet? The FDA lists other typical side effects of this medication as possibly including nausea, dizziness, headache and increased urination. However,...

62 REPLIES

SInce being switched from lisinipril 20 mg to Losartan Pot 50 mg about three months ago I have gained 12 pounds and always feel hungry. I also feel jittery. Could this be a side effect of Losartan Pot? ## Yes, these can be side effects of taking Losartan, especially the appetite change and weight gain, that has been reported in up to 4% of the people that take it. Learn more Losartan details here. Have you talked to your doctor about it? It just may not be the right medication for you and you may need to switch to something else. ## This is very interesting to read. I was looking for different side effects because I'm having trouble with serious muscle and joint pains, but have also gained about 12 pounds and eat constantly. I'm in the process of working with my dr to switch med...

28 REPLIES

What is the most weight lost by anyone on this drug? I have been taking it for about 3 mos. and have lost weight, but I do not know what is normal. ## This is a medication used to treat high blood pressure, it contains a diuretic, so it does remove retained water from the body, but IT IS NOT A WEIGHT LOSS DRUG. ## i was wondering how long it takes for detrol la 4mg to start to work ## VERWON, I am taking this medication for high blood pressure and not for WEIGHT LOSS. I am concerned I may be losing too rapidly. That is why I asked. My question may have been misunderstood. ## I have been taking this drug Triamt/Hctz for over 2yrs now, and i have lost some weight not a whole lot, but i was just wondering if the drug is known to cause weight? I know its not a weight loss drug!...but weight...

8 REPLIES

I started metoprolol about 6 months ago, and after a few weeks on it, I started having pain in my upper legs (thigh area) and sometimes lower legs. I complained to Dr and they say it’s not from the med. I never had a leg problem and it’s getting worse. After sitting, when I get up my legs feel heavy and painful. Had anyone else had anything like this? ## Hi Jojo, Sorry to hear about your situation. Leg pain unfortunately isn't listed as a side effect of Metoprolol on NIH.gov or Medlineplus.gov. However, they do list swelling (inflammation) of the legs, which I believe in turn can correspond to pain. Source: [1] medlineplus.gov/druginfo/meds/a682864.html [2] ncbi.nlm.nih.gov/pubmedhealth/PMHT0011186 There are also a couple other popular discussion threads here noting the ...

6 REPLIES

I have used tab. telma H for around one year. drug has started showing side effects including rise in serium uric acid level to 9.9. Doctor advises me to stop telma H and use telma 40 for the time being. Is it a safe prescription ## Telma H contains both Telmisartan and Hydrochlorothiazide. Telma 40 just contains Telmisartan. As to being safe, there are possible dangers and side effects to all prescription drugs, which is why your doctor should be monitoring your use of them. Some common side effects to Telma 40 may include: nausea, dizziness and headache. You can read more about it here: Is there anything else I can help you with? ## I am using Telma 40 H for the last three months without side effects and consuming alcohol daily ## pls since over 2years i have been taking this telma H,...

15 REPLIES