Camber Adderall Complaints (Page 6) (Top voted first)

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Camber's new generic for Adderall IR 15mg is no good. Prior to it I got 10mg Adderall from CVS and it worked great! Just got a fill from Kroger since CVS was out of stock. The brand is from Camber and not only does it not work, it makes me feel unwell, sleepy and super irritated. It’s crazy how companies are able to differentiate in their generics like they do. This Camber brand just makes me want to go to sleep but I feel so unwell it’s hard to. I can’t focus at all on anything but how sick I feel. Don’t take this new stuff people and if you have what did you think?

135 Replies (7 Pages)

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75

Re: Kim D (# 12) Expand Referenced Message

I am not a fan of Walgreens but use them because of their locations are everywhere and if I have a rx while I’m on the road I can have it filled. Plus they always filled with Teva for my adderall rx. But last month they were out and I had to have the dr office send it to another Walgreens that did have some in stock. I only was able to do that after calling each Walgreens that were within 30 mins away. I just opened my bottle I picked up earlier today and it’s not teva but this cambert stuff and now I’m really worried. I think I’ve had this manufacturers adderall once and it was headache and felt lethargic and grumpy. And worried this is going to be Walgreens new source of genetic adderall.

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77

Re: Kim D (# 5) Expand Referenced Message

Same experience. I am back on Teva

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80

Re: c (# 13) Expand Referenced Message

Been using the Camber 20mg for 2 months now and I swear I feel like I’m about to “start” daily with the cramps. It has also constipated me so that could be the reason for the cramps. Obviously I’m feeling off and figured I would see if it could be contributed to this. I’ve been extra crabby yet sensitive (totally not me at all) and it ALL makes sense now

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89

Re: Ang985 (# 20) Expand Referenced Message

Where is the insult exactly?! Get over yourself & your emotions.... God forbid someone has a positive effect while you didn't.

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92

I'm so glad people are speaking up about how bad the Camber generic adderall effects can be.

I've been taking the Teva generic for 8 months and haven't had any problems (unless I took it on an empty stomach). I'm on a low dose - 15mg/day IR.

Due to the backorder, I had to go two weeks without any medication in late July/early August. When it came in two weeks ago, the pills were white instead of blue and the manufacturer was Camber. At first, it seemed ok, but gradually I feel worse and worse. So much so that I'm taking 5mg/day which does almost nothing for focus.

Nothing has changed in my life stress-wise, but all of the sudden I have insomnia in the middle of the night. I feel kind of blue and have never had trouble with depression. I also feel irritable for no reason. There's something not right about this generic. I really hope the FDA looks into it (I've reported my experience to them). I really feel for everyone who relies on this medication to function. Avoid the Camber generic if you can.

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95

Both 20 Mg and 30 Mg Dextro/Amph-SC by Camber filled by Walgreens produce same effects.

- Left/right brain tingles
- Blood pressure increase
- Extreme fatigue
- Depression

I took 1 half of each on two different days with one full day in between. I slept 12 hours on each dose after 2 hours of ingesting.

Male 6'6 190 lbs

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99

Re: Diego (# 31) Expand Referenced Message

Did you have covid? Seems like everyone is having problems with literally every adderall medication after Covid… it’s hit or miss for me. Usually none work anymore and I can’t get my brain to focus on 1 thing for over 5 minutes. It’s horrible and really screwing up my life. Also after Covid my quality of life been Way down and doctors and family suggest I have ‘long-term covid’.

That’s why I’m wondering if that is what’s causing the medications not to work.

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108

Re: PeterInPalmBeach (# 62) Expand Referenced Message

Did the spider the spravato help you? I've been looking into this..my world has been dark lately.

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109

I had to get Camber last month and had never heard of it. I was fine for the first few days and then I started feeling myself get so irritated and then angry. I was fighting and yelling with my husband over stuff I didn't even know why. I actually started slipping into depression and was feeling unmotivated and even "numb" towards the end of the prescription month. Luckily my CVS had their usual Alvogen in stock this month but I have issues with that too but not as bad. The anxiety I go through every month wondering if I can my medication on time, or at all, or how many days I will suffer without it, which brand I'll end up with, etc.... it's so unfair.

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111

Re: Optimistic (# 1) Expand Referenced Message

Does anyone else get a weird side effect of their tongue getting sore and swollen? Like the taste buds get dark red, swollen and inflamed and it hurts to talk or eat? I noticed it went away when I was off my medication for a few days? If this happens to you please let me know. It has to be the medication for me, no other cause and it always coincides with my medication.

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116

Re: G (# 99) Expand Referenced Message

It is a possibility the long covid is making Adhd worse, as it did for me for a year. Possibly the vaccine also to be honest.
I had the worst brain fog for about a year. It almost felt like I didnt haveo oxygen in my brain. I had yo almost double my adderall dose and it still barely worked.
On another note though, these generics can be terribke with horrible side effects

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122

Re: Optimistic (# 1) Expand Referenced Message

Teva / shire is the best manufacturer. Camber is not the best.

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126

Re: Optimistic (# 1) Expand Referenced Message

That information is 100% incorrect and what most people believe (I even propagated something like that early on too). I'd recommend you do a search on how bioequivalence is established. It is based on blood concentration of the API (active ingredient) at set time intervals in the same person in a ratio comparison to the brand name drug. If you find a source that doesn't mention the geometric mean, AUC, BAC and stuff like that, keep looking because it is not the right information.

The difference between a crap brand like aurobindo etc. is that the excipients (inactive ingredients) are either not helping or interfering with the API crossing the blood brain barrier. I don't know if the excipients used by the good brands help or are neutral in helping the API cross the BBB or if the crappy brands are neutral or inhibit the API crossing the BBB. I'd have to look at individual excipients to try to figure that out which is more effort than I want to put in.

So, bioequivalence is all about absorption rates of the API and half life elimination. Which assumes therapeutic equivalence but never actually tests for it. Passing the BBB is required to actually be therapeutic and not factored in. Which is why we see the difference between crappy and good brands that can/can't pass the BBB well. There is a good historical reason why therapeutic equivalence is assumed for most drugs based on bioequivalence. Generic psychoactive drugs based on amphetamines like Adderall, Dexedrine, Zenzedi, Vyvanse, etc. seem to be highly effected by the excipients and given all the complaints over many many years, the FDA is screwing this issue up big time which screws the rest of us.

Tell your therapist to put on the script the brands that work for you and the pharmacy will only fill with one of those. If they don't have one available, transfer to another pharmacy that does. Which is why I prefer hand written scripts since in a time of shortage I've had to go pharmacy to pharmacy trying to find what brands work for me. You can't as easily go to a dozen or more pharmacies with those stupid electronic scripts the doctors send. Also look into what information needs to be on a written script if you get one. My doctors office screws that up most of the time and I often have to go back to get it filled in correctly. Such a ridiculous system.

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127

Re: Ang985 (# 3) Expand Referenced Message

From what I have read, people really liked Lannett till around July of 2022 when they had to change their formulary. It was originally manufactured by Elite Labs Inc. and marketed by Lannett. Elite decided to market their own drug themselves which is why Lannett had a new formulary after July 2022 which people didn't like.

Good news is, Elite is the same formulary of Lannett that people liked before July 2022. I've neve tried it myself, but am curious to see how I would respond to it given the mostly positive reviews in the past.

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129

Re: Rick J (# 15) Expand Referenced Message

Bonus points on mentioning withdrawal. Most people blame that crappy brand for all their symptoms not realizing much or most of what they are experiencing is withdrawal. Which may be made worse by low quality excipients in some generics like Camber.

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130

Re: Caitlin (# 17) Expand Referenced Message

Funny you mention the 1.5 months of the crappy generic. Due to shortages every few years and taking less than prescribed when ever I can get by on it. I had over 5 months of a crappy brand lined up before I realized I had been switched to it (Aurobindo/aurolife white labeled as Norhtstar).

Was going nuts for over a month trying to figure out what went wrong before I realized it was the brand that got switched on me. Corepharma and Aurobindo have the exact same size, shape, and score pattern on the drug. 20mg Corepharma is pink while Aurobindo is orange. But, while still in bed with the lights off, they look exactly the same. Thought it was due to other medication changes I had around that time that were giving me bad side effects. Then finally, over a month later looked in the light of the bathroom and realized they were a light orange not a light pink. Ughhh! This was in 2022 in the middle of the shortage.

Titrated aurobindo up to 100mg from my usual 40 of Corepharma that I start my day with. Then took 40mg more a couple hours later. Still less effective than my 40mg corepharma that I would only sometimes bump up with 10 or 20mg in the afternoon if needed.

Also, one of the clues that led me to understand the problem was the active ingredient not passing the blood brain barrier. After a few months and ran through the less effective even at triple the dose Aurobindo, I did not have increased tolerance in my brain. Which means it couldn't have been passing the BBB. Then read about how some excipients can help certain drugs pass the BBB. And learned how bioequivalence actually works (most people get it wrong).

Things were ok for a month or so. Then I started taking Mounjaro for diabetes. Which was a whole nother more complicated issue. It can help, hinder, or be neutral in regards to signaling in the pre frontal cortex. And science isn't yet able to predict which effect someone would have. For me, it blocked my adderall (and any psychoactive medication from working) in my case which again, I had changed other medications that were giving me bad side effects and thought it was that etc. Ugh!! Again, eventually up to 140mg of adderall, but this time it was Teva or Sandoz. Which didn't work at all in the end. Found out too late that although it wasn't allowing psychoactive meds to have a therapeutic effect, they were damaging/downregulating my brain unhindered at the high dose which persisted the tolerance/side effects after I stopped taking Mounjaro many many months later. The positive side effects some people have with Mounjaro and other GLP-1 based drugs are being studied for possible second line medications for things like depression and anxiety. Some peole on psychoactive meds having huge benefits from GLP-1 based drugs.

For the people with negative side effects like me, industry is doing a good job of trying to hide that fact. Even did a fake research article on people reporting issues in social media to discredit people self reporting negative side effects. Which if you read closely, excluded people like me taking psychoactive meds and getting interference from the statistics. Needless to say, there are zero statistics on incidence rates for those with negative cognitive side effects ranging from simple brain fog to some people with bi-polar disorder having to be hospitalized to rebalance their neurotransmitters. Welcome to America. Land of the free and home of the screwed by corporate industry. And left to fend for ourselves by a certain political party that prefers to defund government agencies that regulate like the FDA, making them far less effective and able to do much of the things we would expect them to. Combined with FDA incompetence on some issues like these.

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131

Re: NotAJunkie77 (# 19) Expand Referenced Message

You need to understand that people respond to drugs in different ways. Some people take Adderall and it puts them to sleep while others get wired. Some people respond to 100% dextroamphetamine better than any combination with levoamphetamine. Adderall is 75% dextro and 25% levo. Some find that works better.

Generally dextro acts more on the brain while levo acts more on the cardiovascular system. Increase heart rate and respiration, more circulating oxygen, more stimulation. So, you can see how some respond better to something like Adderall.

Evekeo is 50/50% dextro/levo. 15% of people respond better to that combination. Which could possibly be many of the people who may respond better to generics that don't work as well for others.

The main issue is low quality vs higher quality inactive ingredients. Which, unlike the name, are not always inactive. "Inactive" ingredients all have their own drug profiles and may help people to respond in certain ways to the active ingredient or may boost or inhibit it. Or add their own unique effect. The big issue for those whose generics don't work compared to others is likely due to excipients helping, hindering, or being neutral in aiding the active ingredient to pass the blood brain barrier for them. i.e. the better brands may have an Adjuvant - " ingredients that modify the action of the main ingredient in a solution or prescription, or enhance the effectiveness of a medical treatment".

As a quick excipient example. Calcium Carbonate is a common excipient (again, inactive ingredient) used for things like diluent, improve dissolution rate, opacifier, and dissolution adjuvant in tablets. At the same time it also acts as an antacid. Which, for someone with a lot of stomach acid may enhance absorption of Adderall (amphetamine). Amphetamines are a weak base. Which can be ionized by stomach acid. ionized amphetamine has a harder time being absorbed. It is also how it is eliminated through urine which would also make it last a shorter time. Having calcium carbonate for whatever reason could easily improve absorption for someone with strong stomach acid. Who may report that brand more favorably than someone like me who takes omeprazole to suppress stomach acid.

So, not only do people respond differently to the actual active ingredient, people also respond differently to the inactive ingredients which can make a huge or no difference between brands for them. Most people respond best to 100% dextro for the therapeutic effect. But I prefer the weaker 4 mixed salts of Adderall myself because of the smoother transition for onset/offset. Evekeo just plain sucked for me being too weak, not enough dextro.

40mg corepharma, teva, sandoz, shire, barr would wake me up and get me out of bed in 20 minutes. Aurobindo, sun pharma, and more, 100mg, I had to set my alarm 2 hours later to be sure to wake up and get out of bed. There is nothing psychosomatic that would account for that difference. Especially when I didn't realize I was switched to Aurobindo and thought I was still taking corepharma.

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132

Re: James (# 121) Expand Referenced Message

It's funny, Mallinckrodt from what I have read from others has very mixed reviews. More so than any other brand. Having tried it myself, it isn't a good brand, but can be good enough when nothing good is available. At least, that is how I respond which was often shared by others.
For me, bad brands, aurobindo/aurolife, sun pharma (formulary taken over by Frontida BioPharm Inc. which may be sold as Sun or Frontida). Both of which have been white labelled as Northstar brand. Epic, the new Lannett formulary post July 2022, accord / Intas, Camber, Granules. Basically, for generic Adderall I avoid any brand that is or is owned by an Indian or Chinese based brand. Nothing against those countries or people. Just that their pharma industry culture is to make cheap generics with lower quality ingredients and too often low standards. Which is where most generics and active/inactive ingredients are based from.

All Adderall is made in the U.S. But, foreign companies do manufacture scheduled drugs in the U.S. Including the brand name as Teva is an Israeli company. Which bought the British company Shire who had the patent before them.

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133

Re: Kimi (# 115) Expand Referenced Message

What happened? Severely poisoned?

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135

Re: HCStymie (# 134) Expand Referenced Message

Very interesting about the excipients. It sounds like a big piece of the puzzle. It doesn't explain why so many people such as myself became profoundly ill after taking Camber, though. I mean, unless one of the excipients is an emetic or something.

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