Camber Adderall Complaints
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Updated
Camber's new generic for Adderall IR 15mg is no good. Prior to it I got 10mg Adderall from CVS and it worked great! Just got a fill from Kroger since CVS was out of stock. The brand is from Camber and not only does it not work, it makes me feel unwell, sleepy and super irritated. It’s crazy how companies are able to differentiate in their generics like they do. This Camber brand just makes me want to go to sleep but I feel so unwell it’s hard to. I can’t focus at all on anything but how sick I feel. Don’t take this new stuff people and if you have what did you think?
Re: James (# 121)
It's funny, Mallinckrodt from what I have read from others has very mixed reviews. More so than any other brand. Having tried it myself, it isn't a good brand, but can be good enough when nothing good is available. At least, that is how I respond which was often shared by others.
For me, bad brands, aurobindo/aurolife, sun pharma (formulary taken over by Frontida BioPharm Inc. which may be sold as Sun or Frontida). Both of which have been white labelled as Northstar brand. Epic, the new Lannett formulary post July 2022, accord / Intas, Camber, Granules. Basically, for generic Adderall I avoid any brand that is or is owned by an Indian or Chinese based brand. Nothing against those countries or people. Just that their pharma industry culture is to make cheap generics with lower quality ingredients and too often low standards. Which is where most generics and active/inactive ingredients are based from.
All Adderall is made in the U.S. But, foreign companies do manufacture scheduled drugs in the U.S. Including the brand name as Teva is an Israeli company. Which bought the British company Shire who had the patent before them.
Re: NotAJunkie77 (# 19)
You need to understand that people respond to drugs in different ways. Some people take Adderall and it puts them to sleep while others get wired. Some people respond to 100% dextroamphetamine better than any combination with levoamphetamine. Adderall is 75% dextro and 25% levo. Some find that works better.
Generally dextro acts more on the brain while levo acts more on the cardiovascular system. Increase heart rate and respiration, more circulating oxygen, more stimulation. So, you can see how some respond better to something like Adderall.
Evekeo is 50/50% dextro/levo. 15% of people respond better to that combination. Which could possibly be many of the people who may respond better to generics that don't work as well for others.
The main issue is low quality vs higher quality inactive ingredients. Which, unlike the name, are not always inactive. "Inactive" ingredients all have their own drug profiles and may help people to respond in certain ways to the active ingredient or may boost or inhibit it. Or add their own unique effect. The big issue for those whose generics don't work compared to others is likely due to excipients helping, hindering, or being neutral in aiding the active ingredient to pass the blood brain barrier for them. i.e. the better brands may have an Adjuvant - " ingredients that modify the action of the main ingredient in a solution or prescription, or enhance the effectiveness of a medical treatment".
As a quick excipient example. Calcium Carbonate is a common excipient (again, inactive ingredient) used for things like diluent, improve dissolution rate, opacifier, and dissolution adjuvant in tablets. At the same time it also acts as an antacid. Which, for someone with a lot of stomach acid may enhance absorption of Adderall (amphetamine). Amphetamines are a weak base. Which can be ionized by stomach acid. ionized amphetamine has a harder time being absorbed. It is also how it is eliminated through urine which would also make it last a shorter time. Having calcium carbonate for whatever reason could easily improve absorption for someone with strong stomach acid. Who may report that brand more favorably than someone like me who takes omeprazole to suppress stomach acid.
So, not only do people respond differently to the actual active ingredient, people also respond differently to the inactive ingredients which can make a huge or no difference between brands for them. Most people respond best to 100% dextro for the therapeutic effect. But I prefer the weaker 4 mixed salts of Adderall myself because of the smoother transition for onset/offset. Evekeo just plain sucked for me being too weak, not enough dextro.
40mg corepharma, teva, sandoz, shire, barr would wake me up and get me out of bed in 20 minutes. Aurobindo, sun pharma, and more, 100mg, I had to set my alarm 2 hours later to be sure to wake up and get out of bed. There is nothing psychosomatic that would account for that difference. Especially when I didn't realize I was switched to Aurobindo and thought I was still taking corepharma.
Re: Caitlin (# 17)
Funny you mention the 1.5 months of the crappy generic. Due to shortages every few years and taking less than prescribed when ever I can get by on it. I had over 5 months of a crappy brand lined up before I realized I had been switched to it (Aurobindo/aurolife white labeled as Norhtstar).
Was going nuts for over a month trying to figure out what went wrong before I realized it was the brand that got switched on me. Corepharma and Aurobindo have the exact same size, shape, and score pattern on the drug. 20mg Corepharma is pink while Aurobindo is orange. But, while still in bed with the lights off, they look exactly the same. Thought it was due to other medication changes I had around that time that were giving me bad side effects. Then finally, over a month later looked in the light of the bathroom and realized they were a light orange not a light pink. Ughhh! This was in 2022 in the middle of the shortage.
Titrated aurobindo up to 100mg from my usual 40 of Corepharma that I start my day with. Then took 40mg more a couple hours later. Still less effective than my 40mg corepharma that I would only sometimes bump up with 10 or 20mg in the afternoon if needed.
Also, one of the clues that led me to understand the problem was the active ingredient not passing the blood brain barrier. After a few months and ran through the less effective even at triple the dose Aurobindo, I did not have increased tolerance in my brain. Which means it couldn't have been passing the BBB. Then read about how some excipients can help certain drugs pass the BBB. And learned how bioequivalence actually works (most people get it wrong).
Things were ok for a month or so. Then I started taking Mounjaro for diabetes. Which was a whole nother more complicated issue. It can help, hinder, or be neutral in regards to signaling in the pre frontal cortex. And science isn't yet able to predict which effect someone would have. For me, it blocked my adderall (and any psychoactive medication from working) in my case which again, I had changed other medications that were giving me bad side effects and thought it was that etc. Ugh!! Again, eventually up to 140mg of adderall, but this time it was Teva or Sandoz. Which didn't work at all in the end. Found out too late that although it wasn't allowing psychoactive meds to have a therapeutic effect, they were damaging/downregulating my brain unhindered at the high dose which persisted the tolerance/side effects after I stopped taking Mounjaro many many months later. The positive side effects some people have with Mounjaro and other GLP-1 based drugs are being studied for possible second line medications for things like depression and anxiety. Some peole on psychoactive meds having huge benefits from GLP-1 based drugs.
For the people with negative side effects like me, industry is doing a good job of trying to hide that fact. Even did a fake research article on people reporting issues in social media to discredit people self reporting negative side effects. Which if you read closely, excluded people like me taking psychoactive meds and getting interference from the statistics. Needless to say, there are zero statistics on incidence rates for those with negative cognitive side effects ranging from simple brain fog to some people with bi-polar disorder having to be hospitalized to rebalance their neurotransmitters. Welcome to America. Land of the free and home of the screwed by corporate industry. And left to fend for ourselves by a certain political party that prefers to defund government agencies that regulate like the FDA, making them far less effective and able to do much of the things we would expect them to. Combined with FDA incompetence on some issues like these.
Re: Rick J (# 15)
Bonus points on mentioning withdrawal. Most people blame that crappy brand for all their symptoms not realizing much or most of what they are experiencing is withdrawal. Which may be made worse by low quality excipients in some generics like Camber.
Re: Kim D (# 5)
It wasn't likely the bad generic making you feel sleepy, depressed etc. It is more likely from dependence on Adderall.
Our brains try to counteract changes made to it by drugs to get back to what it thinks is the natural baseline. So it starts shutting down receptors to decrease the boosted signaling drugs provide. After a while many receptors will be absorbed and taken out of action. So when off the drug, you now have less receptors and no drug boosting the neurotransmitters so you would be worse than your normal premedicated base line. Then factor in how amphetamines even at prescribed doses can cause damage in other ways that add to tolerance.
In other words, you have become dependent on the drug just to be able to get back up to your natural baseline nevertheless getting to a therapeutic effect. Which, if you stop taking the drug, it is also know as withdrawal. Usually it is not too bad at low doses and for many at mid level doses. Some even don't have issue at higher doses. Me, ruined my life with accumulated side effects at and below prescribed doses. Not the most typical response, but not totally unusual. Hence all the research I did on it.
Not to be confused with addiction. Addiction includes dependence, but dependence doesn't have to include addiction. With addiction, that would additionally involve physical and/or mental cravings, often sickness like nausea, cold sweats, shivers, tremors, headache, etc. Cheap excipients can cause things like nausea, headache etc. as well as dependence does when you stop taking the drug, or take a crappy generic that doesn't work which has the same effect as withdrawal but may actually make it worse with the low quality excipients side effects.
Funny thing is, amphetamine based medications are actually less addictive than caffeine when caffeine is paired with sugar like in soda. And far less addictive than nicotine in cigarettes. I've talked to people who have exceeded 300mg of the good brand of generic Adderall a day and still only been dependent and not addicted. Unfortunately, people with very high levels of dependence like that can take over a year to renormalize their neurotransmitters while off it.
For me, if I take some Adderall it gets my brain going but I can feel a bit shaky and uncoordinated and somewhat hyperactive yet sleepy at the same time. So I have to take more to get to a functional dose. Taking none. I am just sleepy, grumpy, unfocused etc. as I have high dependence and working to get off it forever. Again, I am not the most typical case, most people are stable on their dose, but should be aware if they have issues with dosage escalation, high tolerance, high or accumulating side effects.
Re: Ang985 (# 3)
From what I have read, people really liked Lannett till around July of 2022 when they had to change their formulary. It was originally manufactured by Elite Labs Inc. and marketed by Lannett. Elite decided to market their own drug themselves which is why Lannett had a new formulary after July 2022 which people didn't like.
Good news is, Elite is the same formulary of Lannett that people liked before July 2022. I've neve tried it myself, but am curious to see how I would respond to it given the mostly positive reviews in the past.
Re: Optimistic (# 1)
That information is 100% incorrect and what most people believe (I even propagated something like that early on too). I'd recommend you do a search on how bioequivalence is established. It is based on blood concentration of the API (active ingredient) at set time intervals in the same person in a ratio comparison to the brand name drug. If you find a source that doesn't mention the geometric mean, AUC, BAC and stuff like that, keep looking because it is not the right information.
The difference between a crap brand like aurobindo etc. is that the excipients (inactive ingredients) are either not helping or interfering with the API crossing the blood brain barrier. I don't know if the excipients used by the good brands help or are neutral in helping the API cross the BBB or if the crappy brands are neutral or inhibit the API crossing the BBB. I'd have to look at individual excipients to try to figure that out which is more effort than I want to put in.
So, bioequivalence is all about absorption rates of the API and half life elimination. Which assumes therapeutic equivalence but never actually tests for it. Passing the BBB is required to actually be therapeutic and not factored in. Which is why we see the difference between crappy and good brands that can/can't pass the BBB well. There is a good historical reason why therapeutic equivalence is assumed for most drugs based on bioequivalence. Generic psychoactive drugs based on amphetamines like Adderall, Dexedrine, Zenzedi, Vyvanse, etc. seem to be highly effected by the excipients and given all the complaints over many many years, the FDA is screwing this issue up big time which screws the rest of us.
Tell your therapist to put on the script the brands that work for you and the pharmacy will only fill with one of those. If they don't have one available, transfer to another pharmacy that does. Which is why I prefer hand written scripts since in a time of shortage I've had to go pharmacy to pharmacy trying to find what brands work for me. You can't as easily go to a dozen or more pharmacies with those stupid electronic scripts the doctors send. Also look into what information needs to be on a written script if you get one. My doctors office screws that up most of the time and I often have to go back to get it filled in correctly. Such a ridiculous system.
Re: c (# 13)
I got severe lower abdominal pains. Very nauseous, headache, fatigue, unable to focus. I couldn't even do my job at work kept nodding off. The Camber Generic is very toxic!!!
I have taken Adderall IR for ten years and have been taking it for ten years.
Recently they gave me Camber.
There is no doubt something is profoundly wrong with this product.
Camber brand does work but it’s less potent.
Re: Optimistic (# 1)
Teva / shire is the best manufacturer. Camber is not the best.
Re: Kimi (# 120)
I have taken generic Adderall IR 30MG for 10 years for narcolepsy.
Thus, I have had many generic brands.
The two I would avoid at all costs are: Camber and Mallinckodt
Re: Kimi (# 115)
I agree. I made a complaint 6 months ago to the FDA and Camber is still putting the life’s of people in danger until today
Re: Chuggle (# 117)
I reported this medicine to the FDA. It felt like poison . If your Stomach and mental health is being affected because of a medicine, why would trust to continue taking it?
Re: Comments Submitted (# 82)
Yeah, I call the evil twin generics "Badderall". But this Camber stuff is on a different level, it should be called "Wirstavall". Seriously though, isn't it odd how they managed to formulate it to give almost the exact opposite effects of what it's supposed to do? It's actually amazing, or at least it would be if I could feel anything on this god awful stuff. With this many people having issues you'd think there'd be a legal suit or an investigation or something.
Yeah, it's junk. I've been taking Camber 12.5 for a week... the side effects have subsided a bit, but it's still very ineffective. It makes me feel ill, tired, and clumsy. My stomach is really having a hard time with it. Mentally, my thinking is disorganized and a depression hangs over me.
Do these companies actually try their stuff out on people before they produce and sell it? Because I can't imagine anyone saying this formulation is acceptable.
Re: G (# 99)
It is a possibility the long covid is making Adhd worse, as it did for me for a year. Possibly the vaccine also to be honest.
I had the worst brain fog for about a year. It almost felt like I didnt haveo oxygen in my brain. I had yo almost double my adderall dose and it still barely worked.
On another note though, these generics can be terribke with horrible side effects
Re: wpbgal42 (# 112)
You should fill this form up. Let the FDA know about yr experience. I was severely poisoned by camber’s "fake" adderall and they are not being held accountable.
https://www.accessdata.fda.gov/scripts/medwatch/index.cfm?action=consumer.reporting1
Re: mmmac (# 113)
Good luck! I hope Vyvanse will help you. Maybe your doc can prescribe 45 mgs if it comes in that strength. Or you could go in at 50 mgs. I’m unsure if the dosage corresponds to weight or symptoms or a combination of both, but it’s def worth a shot. Let us know how you do.
Re: Janalyse (# 101)
You’re totally correct!
I tried Vyvanse about 6yrs ago and it didn’t seem helpful @30mg.
However, last month my current doctor & I actually did discuss trying it again due to the Camber issues, ideally at a slightly higher dosage.
So that will happen next month and I’m very hopeful it will be successful.
Especially now that my other meds are brand name only and am not fighting the side effects of the inactive ingredients in generics of those.
The Camber generic does feel like poison and I’ve almost weaned myself off it entirely.
Until my next appointment and switching to Vyvanse, I’d prefer to fall asleep randomly and explain the disorder after if necessary over what this seems to be doing to my body and mind.
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