Brintellix (trintellix) Withdrawal
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Started 10 mg Trintellix 3 weeks ago. Vomiting at least 2x a day and constant nausea, fatigue, muscle and back pain. Trying to wean off it - doctor said take it every second day for a week then go see her. What is the normal time frame for withdrawal? I am terrified of this drug. I am diabetic and it is making my sugars wildly fluctuate too.

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REPORT

I have been on Trintellix for 16 months. I started on 10mg and shortly after I increased to 20mg. Before Trintellix I was on Prozac 20mg for 3 years.

Around April of this year the medsstopped working and when hopes were lost my doctor asked to taper it off. After being on 10mg for a week, I felt great and told my doctor that I would like to remain on 10mg. Fast forward to now, the meds stopped working again. Fog, fatigue and excessive sleep for the past 2 weeks.
Starting tomorrow I will do every other day, technically moving to 5mg and see what happens.

I want to come off and might test escitalopram.

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How are you feel now? Are you on anything? I'm trying to be med free

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Re: Click (# 5)

I wonder (honestly) how day 6 - 10 were? I did the same thing. The first 5 or 6 days were fine, but when the second week kicked in, wow! Headaches, nausea, instability, shaky, it was horrible. But during that first week, I felt great! Now I'm on it every other day and scared to go to every two days.
Trintellix steals my emotions and causes weight gain.

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I feel like now that I'm off of it I wake up shakey.

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Re: Nicola (# 20)

Withdrawel from Trintellix can be severe. I'm currently located in Norway where Trintellix is called Brintellix. In the Norwegian guideline for doctors it says that you can stop cold turkey on the meds. After using Trintellix for 1 year on 20 mg a day I wanted to stop using them. My doctor just looked up in his book and said: it says here you cant just stop taking them . There will be no withdrawel symptoms.periode.

So I trusted him and then the hell broke loose. Shivers, brain fog-felt like my brain was num, poor vision, dizzines, nausea, agression, out bursts, tears..and so on..almost the same hell as when I weaned off Paxil..I tried to get information from Lundbeck, but they just said that according to our trials no one in the trial group reported withdrawel symptoms. The norwegian health board says: Ok , Lundbeck we trust you. Lunch and golf next week as usual? It's a joke. But I'm hanging in there..slowely weaning off this poison. Now down to 5mg a day..writing my masters degree thesis at the same time and it's a nightmare. Go slow is my advice. Eat healthy, exercise, stay away from alcohol for a while (a beer or two is prob. ok), take amino-acids and think that one day it will all be good again..hopefully

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Done taking this medicine. I have been slowing weaning myself off of it over the last two months. Was taking 20mg. The severe night sweats continue. Now insomnia as well. Extreme exhaustion. Vertigo was an issue in the beginning. But I can tell over all I am doing better mentally. I was able to read 25 pages in a book for the first time since being on it. I just want all the side effects to end!! Haven’t taken any in 3 days now.

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Re: Joshsgirl (# 16)

Omg joshsgirl, you're the only other person I know that's felt the tingling all over (strange sensation). I'm currently on day 16, first week on 10 then 2nd week on 5mg and then stop. This is day 2 with no brintellix and still feel like s*** however it could also be side effects of starting seroquel.

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Re: Nila (# 17)

I am off of trintellix for the first time in at least 2 years. A lot of your side effects especially the insomnia have been really difficult - how are you feeling off it now? I’m cautiously optimistic aside from the lack of sleep so far.

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Re: Click (# 5)

after all these months...how are you feeling now...

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Re: usurpossum (# 15)

I have been on this med for a year and feel like my depression and anxiety are worse recently. Also have insomnia that is worsened on this med. Side effects of wt gain, sweating and itchiness as well. I tapered my dose now to 10 mg. It's been about 6 days and experiencing muscle cramps in hands and feet. Plan on taking every second day now. Hopefully this will subside.

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Re: usurpossum (# 15)

I just stopped it a week ago and I have been dealing with my heart racing and I feel weirdly tingly all over. So far that is the only sypmtoms I have. I would love to know how long this lasts though....this feeling is for the birds....

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Re: Zee zee (# 12)

I just stopped Trintellix. I've gained at least 10 pounds over the 3 or 4 months on it. When I told my psych I was gaining weight, she attributed it to this med. I believe last night was my last pill. Maybe it's my imagination, but I feel like my heart is racing today. I can only hope my Ambien and muscle relaxer will help me sleep and it will pass. I'll try to post again...if I find my way back to the board.

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Re: Greg (# 4)

my experience sounds exactly like yours...i am also going to stop...but get dizzy when i went from 10mg to 5 mg...don't know what to do...it has made me feel more depressed than I have ever felt in my life

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Re: Zee zee (# 12)

Just a little info for anyone taking this. I started it about a year ago. It took a few months to kick in. But if you can handle the wait time. It could help you...but everyone's different. Also my doctor made me stop cold turkey 2 days ago until I can get my blood pressure back on track. I was devastated. So far I am having bad headaches and body aches. I'm hoping I get back on it soon. It took a while bit it did help

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Re: Kywoman (# 3)

Did you figure out how to taper off? I am in the same situation. Also how much weight did you gain? My doctor said it shouldn't cause weight gain it I have also gained a lot of weight and think it might be the Brintellix. It hasn't helped that much with my depression so I don't mind going off it. I hope you have found suitable replacement medication. Thanks!

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Re: Click (# 5)
I read your post about withdrawing from Trintellix and I'm hoping you will post about your experience and how you're doing now. I'm in the process of withdrawing from this drug as well and would benefit from your experience.

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I took 5-10 mg of Brintellix for 5 weeks. Didn't like the brain fog. Was told by my MD to stop the current dosage of 5 mg after 3 more days. Since then my brain fog has not cleared. Any idea how long approximately before I get relief? My brain has always been sensitive to this type of medication.

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I take mine at night because of the nausea. I am presently weaning off this med. Dr. Advised me for first week take every other day. Second week, every 2 days, etc.

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Nausea and vomiting are transient side effects that some people might experience for the first 2 weeks. You can stop the medication if you want.

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Well , a bit of a failure. I went to 10mg and stopped taking sleeping pill too.
I ran out of 10 mg after 5 days , after a few days without i went bAck to the 20mg.
I am going on bike ride in early morning and falling asleep around 8 or 9..
Oh well , no sleeping pills is great for me .i see neuro doc next week and will ask her for 10 mg . If i can stay on my bike i will just stop within a few weeks.
Thanks for asking.

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