Nuvigil Side Effects (Page 4) (Top voted first)

I'm having severe side effects from nuvigil. Muscle and joint pain with numbness and tingling down my arms.

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yes I have, it caused inverted T waves, shortness of breath chest pains. I had full work up on heart.

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I am taking nuvigil and metformin extended release too. Not sure which on is making me sick to my stomach and messing my head up.

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Let me just say that i never suspected that the symptoms i was having was the nuvigil because of how it helped so much in the beginning! Extreme joint pain ...extra tiredness ... day 2 of not taking it and felt almost 100% better... went through so many test and dropped a couple other meds before i finally decided to not take the nuvigil. ..i have narcolepsy and am prescribed 250mg ... i have nothing bad to say about this drug because for the last 7 months it was a life saver... but now i must seek a diffent way to stay awake!

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Anger, nervousness, easily angered, flies off the handle, very emotional - cries easily.

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I have been getting neck and shoulder pain. Along with ears and head.

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Im going through the same feeling im bloated and stomach is burning and bubling

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I started taking 200mg if Nuvigil this morning at 9:15. Felt pretty good all day. Thus evening about 12 hours after taking it started feeling nauseous, having chest pains, chest feels heavy and tingling in my body. Has anyone else had these symptoms after only one dose of this stuff. Do I need to be checked out or will these symptoms subside as the night goes on? Def calling my dr Monday morning. Not taking any of this tomorrow either.

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My 2nd day on 250mg Nuvigil. I've chewed a hole in my lower lip and my heart is racing.
I've accepted that I'll be up all night but this is not a med I want to take.

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Yes I do. But I am experiencing nausea, bloating, and pain just under my rib cage. I'm on the 250mg dose. May try halfing it.

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Are you on the generic version? I have been having all sorts of stomach issues with it.

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Ive had shortness of breath for 6 months on nuvigil and ggonna stop it immediately. Hope my breathing gets bette

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Woa stop taking it! Sounds like a heart attack or stroke.

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I had horrible side effects I felt like I was on speed couldn't sleep at night confused and didn't want to continue living on that way I quit taking that but it took a week before I began to feel normal again Took me a while before I figured out what was making me go crazy

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Went from adderall to nuvigil. The doctors are getting BIG kickbacks for this drug. It's a $900 p/m drug... So they are going to fight to keep you on it. I had an allergic reaction on the darn stuff, my former doc KNEW it was a huge issue and took me off immediately. It's been 4 years. I told my doc I started breaking out itching all over that only got worse and never stopped Even 12+ hours after taking the tablet. He just said to lower the dose and keep trying to "make it work"-- now I'm worried because I'm reading about s.j.s and all these HUGE warnings about itching with this drug... I'll be looking for a different doctor Monday morning.

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I am also on Nuvigil for Narcolepsy and Shift Work Disorder and experience similar side effects. From what I have read and can understand, Nuvigil blocks the reuptake of dopamine creating extra-cellular levels, however it does not increase dopamine production. Because of this method of action, Nuvigil can become ineffective and have increased side effects after just a few days. Dopamine is often the nurotransmitter related to our "pleasure center," increasing feelings of wakefulness, euphoria and even pain relief. So when the initial boost of extra-cellular levels of Dopamine decline, we begin to experience pain, depressed mood and reduced wakefulness. Nausea, headaches and muscle/joint pain are listed as common side effects of Nuvigil. Increased anxiety and heart rate are also common which could explain the feeling of irregular breathing. The best advice I have come across to reduce these symptoms is to only take the medication when absolutely necessary. I choose to have my "off days" when I am off work. Unfortunately, on these days, I can barely function and still experience the negative effects which makes life very difficult as I am a single mom. I have also read of people cycling their Nuvigil where they take it for two weeks, one week off, one week on and two weeks off. For me, that does not seem like a feasible option so you would need to take into account your own life style, schedule, etc. and discuss it with your doctor. I hope this helps.

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From my experience with insurance, the most likely reason they will not pay for it is because treatment of MS would be an "off label use," so insurance companies want documented proof that MS specific treatments have been ineffecrive for you. I have Narcolepsy and Shift Work Disorder and my insurance still would not cover Nuvigil until I had tried Provigil as it is cheaper.

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My head felt like there was a hamster on speed running around on a wheel it was horrible

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For chronic fatigue I valiantly tried to make Nuvigil work for me on & off for years and end up going right back to Generic provigil. 2-3 pills in of Nuvigil. I start to feel it coming on & get then the stomach spasms from Hell begin then Fever body aches, Ringing in my ears. This drug is in need of a serious over haul in my opinion. it’s truly a waste to have a potentially wonderful life changing medication not do what it’s designed fully to do.

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mark,what dosage are you taking and for which condition? I'm experiencing sleeplessness at night and wakeup briefly about 4am.

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I have been on Nuvigil for a two weeks for Idiopathic Hypersomnolence (like narcolepsy but worse). My heart is pounding all the time, even in bed, and I often have tingling in my forearms and hands. I am sometimes anxious and irritable and often feel confused, can't concentrate. Thanks for posting. I will call my doctor tomorrow. Did everyone get a proper sleep lab with their diagnosis. I was on Ritalin for 10 yrs. for narcolepsy before I found out I had idopathic hypersomnolence from a sleep lab (Univ. of Chicago). Sometimes had rapid heart rate with Ritalin but it kept me awake. Did not have heart issues with Provigil (just issues with affording it!)

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Started taking nuvigil 250 mg 2 weeks ago. Today noticed bloody stool is this a common side effect? Can't find any i...

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I started nuvigil 1/4 of 150mg tablet or 37mg in the morning. The first two weeks were great , it was like my mind was a...

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Been doing some research on Nuvigil. On day three with no major side effects, light headache and slight dry mouth. Wife ...

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I have been taking Nuvigil for a week to treat shift work sleep disorder. The first two times didnt have a huge effect o...

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