Prolia Side Effects (Page 53) (Top voted first)

I would like to know of any side effects others may have experienced after receiving Prolia infusions. Up to now I have none.

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I have several friends who are doing very well on Prolia but I have opted not to take it even though the last bone test said I have severe osteoporosis. I would be the one to have all the horrible side effects or not but not willing to take the risk.

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I finally found a good endro doc who has worked with me for a year. 75 mg. of Armor Thyroid did the trick. Keep working to find what will work for you

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Got my 2nd Prolia injection June 26th. What a nightmare...headaches, hair loss, pain, nausea, first skin infection (cellulitis), seven days after injection, on iv antibiotics for a week. Seven days later bullous pemphigoid, autoimmune skin disorder, on steroids for three weeks.....was off steroid for 3 days and broke out in a raised, red, very itchy rash all over my body...on steroids for another week and now it is September. THIS DRUG SHOULD NEVER HAVE BEEN APPROVED!!! Right now I am so angry at the drug companies, pharmacists and doctors, who seem to be willing to push any new drug despite the consequences... What can we do to stop this drug in its tracks?

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We are keeping our eyes open for an attorney or form that will take a class action suit. I hope everyone is recording and datinh all that is going on with them.

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I had three prolia shots. I began to develop many of the negative effects immediately but didn't connect the onset with the drug, because by the time I was ready for the next shot the symptoms had abated to some degree. I had described to my prescribing physician after the second shot my concerns which were dismissed. My family doctor took me seriously enough to have me tested for Parkinsons's, MS, and even Alzheimers, as well as neuro-muscular issues as I was so unlike myself. Only after the third shot as I lay in bed one morning weeping because the pain in my legs that went straight through my bones (or so it seemed) was so bad that I began to seriously sort out the variable(s) in my life that might be responsible. Prolia was the only thing that came to mind. So I googled it in the middle of the night and encountered all the symptoms I was experiencing. As it was the weekend I went to my pharmacist the next day and he went to his reference sources (even though they are not allowed to dispense the drug) and came back with the same list I had found. I met with my family doctor who immediately reinforced my estimate and said "no more" but also said I was the only patient that had responded that way. It has now been more than 6 months since my FINAL shot and most of the symptoms are lessening. However I still find walking any distance an issue (at it's worst I had to make an actual decision about going out to ;pick up the mail and frequently let it go for more than a day rather than make the walk). I have worked with an accupuncturist as well as a masseuse and have found some relief in that way. At least the psychological effects have abated as has the constant trembling.

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Hi All:

Just saw a new GYNO. She tells me Prolia works just like Actonel and Fasomax. It prevents old bones from being removed from our body. She said since I had trouble with Actonel and Fasomax, I never should have been put on such a powerful drug like Prolia.

Who do you believe? When I was told I needed to go on Prolia, I visited four doctors, telling them all my problems with Actonel and Fasomax. They all said, Prolia is NOT like the other drugs. If you get side effects they will be little to none.

Every time I speak with a new doctor, pharmacist, etc. I get a new story, is anyone regulating what is going on here? I don't know who or what to believe anymore.

Just saw a feature on this site of 1/2 life of drugs. See the right column, under DRUGS scroll down you will see 1/2 life. You can calculate how long a drug is in your system. When I asked my ENDO how long Prolia is in your systems she told me TWO WEEKS, the Pharmacy told my Two Weeks to 21 Days. If anyone could figure out what is going on, let me know. Amgen says Six months. Side effects just don't go poof at six months.

Let me take a moment to ask all of you to call: AMGEN 1-800 772-6436 and the FDA 1-888 463-6332.

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Kitty~MDs and pharmacists are not geological scientists per se so they would know little about half lives. When you see a show with real scientists wanting to determine an approximate age of something very ancient that was grown on this Earth or made from something grown on our Earth they use carbon dating. That tells them how much carbon is left in the object. Humans too are grown on this Earth so we are carbon based too. Prolia is made from ovaries of Chinese Hamsters so it is carbon based too. It simply means there will always be a molecule or two left in us of Prolia until we die. It won't be sufficient to cause any problems. Scientific fact. This goes for dating any dinosaur pieces found to ancient Egyptian 'paper' to ancient cloth, books, as they were all made from what was grown on Planet Earth and were at one time alive on Planet Earth. Amgen states the half life of Prolia to be 16 days so you can do the math. Amgen also states we should be doing much better in month 5 and they also state that Prolia goes "Poof' in the 6th month. I was doing better in the 5th month but I can tell you honestly that in over a year and a half of one inj. I still have some side effects from Prolia with my major side effect being my spine. It did something to the bones in there that are still extremely painful. I also still have pain in the muscle going up my neck in the arm where I received the inj. It has lessened 75% but still there. My Dr. did not do the inj. correctly. End of the day. She was tired so just grabbed an arm and stuck it straight in - NOT subcutaneously as it is supposed to be given. This is also the arm where I am not even supposed to even have blood pressure taken as it's on the side of a total mastectomy with every lymph node removed. How many ways can something go wrong. She has apologized all over the place and tells me how sorry she is that she made me take it even though I did not want it. I am supposedly her only patient with problems. Not sure I believe that one either. I am happy on Calcitonin and just had a major fall with zero broken or disturbed. Got a little bone bruise was all. That's a very good record for someone that was a -3 in bone density. It works slowly but it works and I am very faithful with it. Mom used it and never broke another bone in her life and lived to 96. She could not even shut the door because a rib bone would snap. She also lived independently in her own home. All we had to do was buy groceries and pay the bills for her as she could not see well in her 90's. She had a lady that came in and cleaned. She fell a lot and could always find a way to get back up with zero broken bones.

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I just noticed on the leaks that HRC took money from BIG Pharma to get their product passed the FDA. I truly believe that to be the case with Prolia. We all know it's a horrid poison that stays in our bodies for years after it is supposedly gone at the 6th month mark. Could she really be one of the reasons we are all suffering with Prolia. Amgen paid Clinton Foundation lots and lots of money to get their drug passed by the FDA? The FDA is now trying to keep up with all of our side effects that were not listed on the original studies. Hopefully, with sufficient pressure, we can get it off the market. Be well all~Pood

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RM~has a MD run a complete lab workup on your Mom like for pre-surgery? I doubt it. Start Mom with 500mg of Magnesium every night at bedtime of her life from now on and for 5 days take a pure salt tablet. That may relieve some of the damage that Prolia has done to her. If that fails, get back with me please. I know when I went to my Primary and he did all the workup, he commented it is unusual for a person my age to be so perfect. I guess he cannot read as I have it all written down in with the meds I take. Sometimes I think our Docs are getting their licenses to practice Medicine at Disneyland. Pood (notice the word PRACTICE)

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They do get a degree to Practice Medicine. We are supposed to believe they know what they are doing. When Celiac came back I had a heck of a time convincing my stupid Dr. He says: Well, the test does have a 10% chance of error." I replied: You have just met one of those 10% chances of error. He shut up and went away. Now my file says: Diarrhea resolved on gluten free diet. I know they are much better in large cities where some of my friends live. I think we get the worst of the lot because people don't want to live here unless they are totally outdoor sportsmen and then they are happy.

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Re your loss of taste, how soon after your injection did you notice it? In my case it was about 2-3 months but I also developed very enlarged taste buds on tongue. Specially at the back so that when I do eat, I get a very bitter taste in my mouth. Also any spicy food stings. My lips are also very itchy and sore. Not to mention the itchy scaly bumps on my legs, arms and chest! I have come to the conclusion that women are treated as Guinea pigs when it comes to anymedical testing of new drugs. First it's HRT , vaginal estrogen , and bone medication. They've now questioned HRT, estrogen, calcium tablets and some bone meds. etc. Meanwhile most long term studies on medical conditions (I.e heart disease) are done only on the prognosis for men! I'm sick of being a Guinea pig and I am seriously thinking of not taking any further medication for my bones. I'm upping my exersize , eating more calcium rich food and thumbing my nose at these mainly male dominated drug companies!

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Anne, I have realized that about eczema and the dermatologist has given me a script which is helping. What is really bothering me is my mouth. So many food items sting when I eat as well as my lips are continuously very sore. I'm also beginning to wonder if my sore muscles in my arms and shoulders are another effect of prolia. I though it could be from all the knitting I've been doing. I have spent too much money on massage and a chiropractor . I think he's even made it worse. Needless( or should I say, needle less!) I have stopped knitting. Even typing this hurts in my upper arm. I am so hopping angry about this whole prolia thing. They phoned me this week to remind me of my next injection in January and I gave them quite an earful. Got no answers from them as to whether these side effects would ever go away.
I was talking to a person I know who had been in contact with the Food and Drug branch of our Canadian government regarding a work related situation and during the conversation it was mentioned how the government is constantly pressured by drug companies to approve their new drugs. There is also much wining and dining
that goes on with doctors to prescribe them . My mother, years ago, worked for a doctor and would tell me about all the free drugs that were given to doctors as well as other perks!

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Sheryl~if it depleted your immune system you would be dead. It knocks off a good 50% to 70% of our immune system. It plays havoc with immunoglobulins. It is just plain and simple a very bad drug that should be taken off of the market in my opinion. Be well~Pood

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And how do I know all about hypoglycemia? My tiny little Poodle had it constantly as a puppy, I didn't have time to get her to Vets in time so they taught me what they did so I could do it at home which is what they do - keep warm (like under an electric blanket or down comforter), Have hot nutritious soups and get sugar in ASAP. I used Karo syrup for her. She didn't want to eat as she was pretty out of it so I had a special high calorie dog food I could mix with water and inj. it in her mouth to get it down her. Same with Karo syrup. The more sugar and good nutrition you can get in your body is the fastest way to get rid of this condition. It also generally starts when one is not having sufficient nutrition for the energy expended. So get busy with the protocol and you will get over this just like she did. Keep warm, eat hot soups or meals and intake syrup or honey and pop of your choice as long as it has sugar in it and high calorie foods. Old fashioned kayo syrup tastes good so drink some. Honey is really yummy so drink a few mouth full of it. It will only help you. Get this under control so you do not get the bad consequences that can follow if you do not. If you have any questions, please feel free to ask me. I am a Prolia survivor and the only reason I stay on this site is to help the ones that come after me. Be well~

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This is good to know - thank you. I have ulcers throughout my stomach and a large hiatal hernia and hate the meds I started, but the dr. said cancer would be end result if we didn't get acid down. I'm bleeding internally from the ulcers. I will be sure to take my meds with plenty of vit C

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Pood, this is really shameful. This stuff is literally pushed on us. Even my pre Prolia research did not prepare me for the possibilities of what transpired. And of course we are not offered the information from Amgen. Have you come across anything that indicated ulcers in the stomach and esophagus? I'm suspicious it is related. Perhaps not, but, dange this stuff is wicked.

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While on the phone last week with a law firm that represents Amgen, they asked me if I was having stomach problems with Prolia. I thought it was odd that they would ask this, unless they have had an uptick in reports? Your thoughts?

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Let me explain this a little for everyone's edification. Prolia needs Calcium and a lot of it. The human body is actually unable to store calcium so Prolia attacks our muscles as that is the only source of calcium in the human body other than what we ingest and delete. When Prolia attacks our muscles, it causes us a lot of pain and I don't like to use that word since it's a loaded word and causes more pain so it's better for our minds to refer to it as 'discomfort' or 'extreme discomfort'. The only thing that can stop that from happening to us is with using a good form of Magnesium. Mine is vegan and it says supports muscle and bone health. Diana O who has been here as long as I have found one that worked well for her. So, if the first one causes bad side effects for you, use a different brand or type. As for the rashes, the only thing that works on them is Prednisone. You can have 10mg of Pred per day for a year while on Prolia as the Prolia is building up bad old bone mass and the Pred will just destroy some of what Prolia has built up. This should never be done except under very certain medical circumstances if one is not on Prolia. It takes a wicked drug to destroy another wicked drug. I also noticed where Amgen did their human study and I truthfully do not believe most of those people have bone structure similar to what we do in the countries in which people post on this forum. We had a lovely lady from China living in Eastern Canada and she got a broken leg for zero reason with Prolia. It's a couple of years back in the back pages of this Forum. The big problem with Prolia is that it is carbon based, just as everything living or having lived on this Earth is. When one takes a carbon based drug it has half-lives that go on to infinity as there is never an end to a half life. Amgen has previously stated that the half life of Prolia is about 16 days so that means in 16 days 1/2 of the Prolia is out of your body and in another 16 days another half of that half on into infinity. That is how we can tell about how old something very ancient is -- by using carbon dating -- meaning how much carbon is left in whatever that artifact is if it lived on our Earth or was made from something that lived on this Earth. There will always be a super tiny amount of Prolia in us because it is carbon based but will cause us zero harm. It came from the ovaries of Chinese Hamsters. Amgen even sent mice into space to see what that effect had on them when they got back. This sounds like science fiction but it is true. Prolia may not have been a super bad drug if it had not bound to RANKL and that L is the most important letter in there as it means our immune system. When the immune system is compromised all kinds of bad things happen and do happen. Diana O. has been searching for an attorney for a Class Action suit but so far, we are not on their radar yet. Every place has a different Statute of Limitations on when you found out from a medical expert that Prolia did x,y,and/or z to you. Where I live it is 5 years but every State in the US is different and so are different countries. I hope this information helps some of you that are going through Prolia. There will eventually be an end to it but again, we are all different so some will get well faster than others while they still struggle to get their lives back. My advice is to get the very best medical treatment you can and if possible, an Immunologist. They are pretty rare it seems but I had one so you can too. Be well~Pood

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Judy~Bursitis would be okay. They just put in an injection of something kind of like Prednisone and it breaks it up. I had one on the back of my knee once and could only walk with a cane. The injection of whatever it was solved that for life. I hope it is just bursitis as it is such an easy cure. We have many bursa throughout our whole body. Just google bursa on humans and you will see how many we have. Be Well~Pood

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Jan~how to you feel otherwise? If cuts are slow in healing it means your immune system is still impaired and that you still have a lot of active Prolia in you. I would think after a year you would be in the 'clear' but it seems you are not. Have the aches and pains quit? Insomnia gone? Feel good like you can take on the world for your age?

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Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happ...

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