Ketamine For Depression? (Page 44) (Top voted first)
UpdatedIt was recommended by the members of a separate thread that one be started that directly relates to ketamine and it's use to treat depression.
If anyone besides myself would like to discuss it's use as a treatment for depression, feel free to post your questions, answers and experiences here.
This thread is an offshoot of a related one that discussed a treatment of Scopolamine for depression.
I had the misfortune of being Dr. Best's pt. for a little while. He is a rip-off artist who does no pre-consult, no post consult, merely doubles the dosage if first one is ineffective, and the trip SUCKS!!
I was pt #1 in a Clinical Study at Alexian Bros. for Ketamine infusion. They used a 50mg infusion 3x per week for 3 weeks, 2x for 3weeks, 1x per week for 3 weeks then every other week for three times. I experienced 'the miracle' after my 3rd infusion and was able to maintain on 1x per week, then depression came back. At NO TIME did I experience any adverse effects, no hallucinations, etc. If you go back to last summer I wrote all about it. Dr. Best wants your money. Period. I am an R.N. I have had depression for 18 years, hospitalized many times. I know how a patient SHOULD be treated. Dr. Best is a total A-hole. No coincidence that he has an MBA as well as an MD. Unless you have a LOT of money, avoid him like the plague. The proper dosage for Ketamine infusion is 1mg/kg. there were a couple of guys in there high as kites. The one told me he was on 180mg. He couldn't stop laughing! I wish I would have had that effect because when he doubled me to 100mg. I was SO f'n HIGH like a BAD TRIP! I saw my recently dead mother and was crying profusely. Not fun. And I used to LOVE to trip back in the day. Watch out for Best, he is Worst.
@catpower wow seroquel & ambien? how do you stay awake at all?
@efesto there is a huge difference between the effects of ketamine @0.5mg/kg and 5.0mg/kg sloppy information could get a desperate person killed if they tried it w/o a doc.
@keller-there are several compounding pharmacies, plus i know an md that has been using ketamine for 10 years and compounds nasal ketamine. First hand I have talked to him and several patients who have used it without effective results. Several doctors in NYC took out a patent on a kit several years ago and dropped it because it is not strong enough. I have not read even one blog with good results.
GLXY-13 would have been controlled along time ago when it was invented. The researcher that did and is now doing private clinical trials with a company can be googled. He has his own website with the co., With a huge photo of himself. They sell it on there.
When they used it in Namenda there were no FDA problems. It is in other medications used for other purposes, which I am trying to find out about.
As I said I have direct link emails with the top, most respected medical journals and there were several articles last week. They started to really surface 6 months ago. I have seen it in the category of supplements. It is already being manufactured.
I am also excluded from clinical trials, but did get it IM. With no results. I have great hope for what they will learn from GLXy-13 and glutamate system and the memory areas of the brain that are all connected to TRD.
@renee- I took Riluzole about a year ago. It's $1500 for 30 days. 1/2 way into the 2nd month I started getting severe side effects. It never helped me. Because of cost etc. I don't think it will ever be an option. Looking hard for GLXy- 13!!!
@keller - there are AT LEAST two sites you can buy it, in a 2 minute search 1st page. would you like them?
pill form only.reputable sources.
NORTH WESTERN UNIVERSITY - INVO -NAUREX: JOE MOSKEAL -"What are the longer term goals for Naurex"? TELLS ALL.
DO NOT REPLY!
@paula - i think a GLYX - 13 thread is a great idea! That is what I want too. How do we start it? It has much more of a future than Ketamine. It will be accessible to regular psychiatrists, it is just a long way off. There is also a Science Blog discussing it now too. There are multiple sources, but the dosages are low. will keep looking.....
@Paula, @Renee, @catpower, @theinvman@Everyone Interested in GLyx-13
WE HAVE A THREAD made by Robert.
Please, lets move there and put our info together.
Especially anyone in a trial.
I think it is the future. It lasts 1 week.
Ketamine is: controlled, too complicated to administer, short term effects and too expensive, etc.
I hope eberyone will post there!!!
@Paula, The study required it (see my over a month ago original post), your location broke the protocol. I do not see why people have such a hard time with this concept.
An equivalent conversation might go:
Me: The sped limit is 35mph
You: That is incorrect I was in a taxi yesterday and the driver went 45mph
The published protocols say there is to be an an anesthesiologist present. Maybe you were under a different protocol, maybe your site broke protocol, I do not know. Maybe you have a link to your study's published protocol? If so please post it as some of us might be able to decrease treatment costs with a different one.
I start LDN in a month, I do not have the 10k required for private ketamine treatments at $600 each + maintenance.
I don't really want to get in a p***ing contest @ Keller, my study was sponsored by Mass. General, which has an excellent reputation. But what I AM interested in is getting better. I have tried LDN(low dose Naltrexone), I obtained some Naltrexone from Canada and put the tiny dose in some water. I didn't have any relief of symptoms, but it's worth trying, I have read some anecdotal positivity. If it is costly for you you can DIY.
@paula Once again you open your mouth before thinking.
I addressed your very issue "There are scattered reports of people requiring more than one treatment to show any relief, but it is anecdotal"
Yes it happens, yes it is very uncommon.
I am glad it worked for you, it may work for others. The data shows the likelihood is much lower and this is exactly what I reported.
You like to contradict everything I post with no good reason. You complained about IN ketamine when I brought it up, now you are looking for it. You complained about my requesting protocols and that centers follow protocols. You just complain about things because I say them, then if someone else brings them up, you are for them. Grow up.
For help, please, please see this article on Ketamine---
theepochtimes.com/n3/84546-treating-depression-with-ketamine-infusions/?photo=2
You could save someone's life- he saved mine.
I have not had ketamine but glyx-13 infusion takes about 5- 10 minutes which includes inserting the IV, flushing with saline, a 3-minute timed infusion, flushing with saline again, taking out IV. There are no hallucinations, etc.
Ketamine treats depression. My stepfather has suffered from PTSD and Bipolar disorder most of his life and Ketamine is the only medication that has brought significant relief to him. When he started the IV treatments, he began weening off some of his prescribed drugs and now he is doing better than ever. He is noticeably happier, more energetic, and has lost weight after stopping his other medications. Ketamine has not only saved his life but it has helped the family be whole again.
I found this page to be helpful and interesting: depressionrecoverycenters.com/why-are-you-still-depressed-4
Hello All,
Since my Dad got killed when I was 15 I have been depressed and embarrassed about it. My doctor prescribed it to me for pain nasal spray. And good lord it works. And what shocked me is after a week on it a 42 year depression VANISHED. When you never fit it and are not good enough and my dr. gave that to me I was elated, However, when I run out the depression comes back but for that relief of pain and depression even for a short time leaves me so grateful. If I ask to get increased a bit I am turned down. My doctor knows best but being sad for all those years and then unbelievably happy is like I finally found the cure but it is not enough, A bit more spray would work, I think the infusions are a rip off since ketamine is an inexpensive drug, It seems like taking advantage of people seem to be the norm or wanting to control them any way they can., Hell I would get it off the streets to enjoy my life again but they scam too, Why is it when something works they control you with it? I just want to smile sometimes and not feel like I don't fit it all the time. I guess that is asking to much, The nasal compound will help you. In as little as 5 days, Unbelievable. I will just try to be grateful for the days I have enjoyed, thanks
@'md'
I am sorry you think infusions are a 'rip off' and that doctors are taking advantage of people. Doctors take a risk any time they prescribe medications that do not have FDA approval for the condition they are prescribing it for, and when that same drug has a large abuse/criminal potential the scrutiny is that much greater. With increased scrutiny comes increased costs and someone has to pay for them. I suspect it will not be until after, if ever, ketamine gets FDA approval for depression that we will see another big price drop. We can hope the nasal Ketamine trials get good results and the protocols get accepted widely as nasal is less expensive, though less effective than IV.
This will be my last posting here, I hope everyone the best. Godspeed!
the reason I think the infusions are a rip off are from what I have been told the prices are outrageous. Ketamine from what I understand is not a new drug but one that has been around for a while. My apologies if I seem to overstate the term rip off but when my doctor gives it to me for pain control as a compounded nasal spray and after 5 sprays it wipes out a 40 year serious depression I don't have anything to compare that with. The price of a nasal spray compound at my pharmacy is 49.00. It is tremendous at controlling pain as well as depression. The good thing that I don't understand the risks is that ketamine is a schedule 4 drug. It has no opiates, nor to my "limited" knowledge does not belong to any barbiturate category. The potential for abuse in my eyes perhaps may be in the young folks need to exploit a chemical for the high. It seems every month I run out early however never once have experienced any withdrawal symptoms of any kind. If I offended a treatment that helps you forgive me. I just sense a hi degree of exploitation when it can be put in a nasal compound for 50 bucks versus what I hear Dr's charge for infusions that seem like another way to make a huge buck. Would just like to see some of these negative connotations dissipate when the benefit of something is as much as what I see in it. I had read they are trying to fastback it for nasal approval for depression when I don't understand why that is an issue when it is approved for pain etc. With what you are saying I am assuming itt must be approved for each purpose. If infusions are helping you and affordable then I am glad for you. Certainly did not mean to offend from my lack of education. I wish you well with whatever route you have available if it makes a difference with anyones depression. Depression is tough on everyone. I hope for there relief from that awful condition anyway they can. Sorry.
You folks seem to be having a time grasping this. So I am asking are there any folks here with access to venture capitalists that would be willing to work with myself and a Neurologists in regards to the amalgamation of the compounded components of ketamine for the purposes of the unbelievable breakthrough in "curing" "CHRONIC" depression. I am trying to assemble a team to work with on this project. My truthful tagline is to say that a person that has not responded at all to seratonin inhibitors over the years can go through this process and actually be "CURED" in less than 7 days from depressions that have sucked tremendous amounts of life from a human being. Please respond {edited for privacy} if you can help. We need you. Thanks
LM DeMarcus
hey, in Los I was looking for any ketamine doctor, but crazy expensive. one session 2000$. maybe the most cheap one is New York infusion therapy.
by the way, why do you think doctor's always use inj. for it? actually,smoking snoozing,drinking, are draining to the internal body. i think inj. is stronger. is it true? and also, how many ml do they use in inj.? too much is dangerous.
One last time regarding your reply. Forgive me. And what you said makes every bit of sense. When you see something that you really feel will help someone you want to expedite that any way you can. I appreciate what you told me, and I have learned a great deal from it. Further more I hold it in regard for you are right, this is not some side of the road peach stand. It is of course big money etc. My enthusiasm is brought on by the response I have had to it so its only a small micro causm I am working with. I just hope that the medical folks will help people instead of these enormous charges of 2000.00 for an infusion. The nasal I am prescribed helps enormously for 49 bucks and that is for "pain" with the added bonus of my "life" back for the first time in years. I have read many similar reactions. Would be great if this choice could be made available for doctors who sense a use for this type of treatment in patients who did not respond to the seratonin crowd. I have never thought anyone would choose to be sad, so if this type of treatment can offer folks help with these type of problems I get excited. Thanks for your words of wisdom. Its not as easy as one would want it to be Im sure. Thanks again
md
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