Hepatitis Forums

Hello. I am 16 months post epclusa and feel worse than when I started. I was a server for over 40 years. Full of energy. Then hep c happened. I had epclysa for 12 weeks. Now I am in bed most of the tune from no energy. My ears are ringing. I feel deflated. Anyone else feel like this? My hep c nurse waived off my complaints. ## Hi Kathleen, I really feel for you, I finished Epclusa a year ago and like you I've had so many side effects l can hardly walk most afternoons due to leg joint pain. I get exhausted so easily, nausea, numb toes/fingers; probably a circulation problem. I did not have any of these problems pre-treatment. I've also got Edema on my legs and my stomach is really swollen. I feel so uncomfortable and unbalanced. If I mention this to the hep C liver people they ju...

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Has anyone experienced severe anxiety, constant crawling feeling in body after epclusa treatment. Its like my brain and body aren't working right anymore? I had terrible side effects. Finished in January, now it's June and feels like I'm still taking the poison. ## Hello, Barbara! How are you? Has there been any change? Those are not normal side effects of this medication according to recent FDA reports. They typical include nausea, dizziness, insomnia, depression, and diarrhea. Are you on any other medications? Do you take any supplements? Do you drink a lot of sugary, or caffeinated beverages? ## Yes I started with hand/arm pain about a month after starting treatment. Now I am three months post treatment and the pain has now been nerve pain in my hands, lower legs, hands, ...

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I have genotype 1a and will begin treatment with harvoni next week. Any advice, information on.1a, my Dr. Said it was a tougher one to get rid of. All enzymes are good, no cirrhosis detected, advice on what to expect would be GREATLY APPRECIATED!! :-) :-) :-) ## That is the geno type I had and my viral load was thirty six million seven hundred twenty thousand and it still worked I was clear after 4 weeks and still after 12 weeks I get a final blood test in September because it can hide in the body so they recheck after 6 months then you know for sure if you are clear or not. ## The FDA lists the typical side effects of Harvoni as possibly including nausea, fatigue, headache, trouble sleeping, and muscle pain. Ref: Harvoni Information Most of the comments from those who've taken it s...

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My feet and legs have always had a swelling problem, but it worsened when I got on Harvoni, and though there never was evidence of a heart problem before, now the doctor wants to discuss heart surgery. Will the symptoms go away when I am through the treatment, or has it caused a permanent problem I need to have surgically corrected? ## If your doctor thinks your condition is severe enough to require surgery, then it is likely not something that's going to go away, even after you finish Harvoni treatment. However, you should get a second opinion, to be sure, and for your own peace of mind, before undergoing surgery. Ref: Harvoni Information What has led your doctor to conclude you have a blockage?

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In early 2019, I began training for a marathon in Vancouver, BC, scheduled for May 2, 2019. Additionally, I was averaging 250 Grouse Grinds per year (often referred to as the "natural stair master"). At 65 years old, I was in very good health for my age. Being able to complete the Grouse Grind in 35-40 minutes put me in the top 10% of all participants. However, in April 2019, I started taking Epclusa. To provide some background: I was diagnosed with Hepatitis C in 1973 in Ontario, Canada. After this diagnosis, I stopped using drugs and changed my lifestyle habits. Despite the fact that doctors and specialists confirmed I was in great shape, the Canadian Medical Association strongly recommended that I take Epclusa. This turned out to be a big mistake. Within one week of starting ...

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Is there anyone out there who has taken Epclusa? I'm fixing to start treatment and would like some feedback. ## When you are starting treatment? Can anyone that's been on this medication chime in? The FDA lists the typical side effects as possibly including headache, diarrhea, discouragement, loss of appetite, and nausea. ## I finished 3 months in Jan; side effects began to like stick to me by the beginning of the 3rd month; swelling for me n nausea, felt a little addicted too; that could have been the habit of taking it at 11am daily. Yet something just isnt right for me n there is no info from the professionals! I'm doing research as much as I can and making adjustments... ## I am currently 12 weeks into a 24 week epclusa treatment. It’s been really difficult due to ...

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Since taking epclusa tx 3 yrs ago I've had edema, nausea, infections, limb pain, and just discovered low vitamin D (had a reading of 20). Any info appreciated, thanks. ## Vit D is fine everything else is a mess we were lab rats search F B And search main drug you will find groups going through same as you I am full of infections viruses and bacteria my ears ring so loud I can’t wakj fro muscle and bone pain and neuropathy I wish there was a way to converse but search and you will. Find the hell we are living in ## Sorry to here your having problems as well, before I started the treatment, the liver nurse assured me that any problems I might have they would be there to help, lol, I saw a liver dr once just to get me signed up,never saw him again, every time I tried to speak to ...

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I stopped the first interferon based meds for hep c1 because of severe rotational dizziness on the slightest movement; this made me vomit and I went to the hospital. I am severely traumatized by this experience and now my doctor tried to insist I try harvoni. I was hopeful at first because I generally read good reports. But, now, looking further into it, I see dizziness is again quite common. I have always been prone to dizziness even as a child I never spun around in games, so I just know there is some inner ear problem and this is likely to happen again. I'm going to ask for another doctor as this one never listens to what I say. I have very low viral load and have been taking ayurvedic medicine: hcv compound. The doctor is well known and holds awards in india and has been nominat...

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I had Harvoni treatment last spring. I am not the same. My nervous system is a wreck. My anxiety problems have increased, depression and lack of motivation. My eyes changed drastically. My thoughts are not focused, I am nervous all the time, can focus or sleep. I had a 2 month migraine. Ringing in the ears is intense. I also was on pigalated interferon and ribivirn, I was pulled off mid treatment because I got so sick. After that treatment, I also had long term side effects. There isn't any back support for post harvoni people, nor are their anyone specializing in the after effect of long term HCV infection, it is NOT just a liver disease, it effects the nervous system and all else. I am at a loss for support with the doctors in my area, none seem to want to do any research and they...

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I have been taking Harvoni for 3 months now and am having nerve pain in my legs and lower back pain. Is anyone else taking Harvoni having any of these same side effects as me? Please help if you are able. Thank you ## Hi Tony, From what I've researched, "lower back pain" is specifically listed as one of the more common side effects of Sofosbuvir (the second active ingredient in Harvoni); so I'd imagine that "leg pain" may be attributed to this drug as well. If you'd like a more concrete reference, "back pain" is also listed as a side effect of Sofosbuvir on Pubmed at: ncbi.nlm.nih.gov/pubmed/25422576 That said, you may want to contact your doctor if the pain becomes too bothersome or severe. This way you and your doctor can determine if Harvoni is sti...

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Has anyone taken Epclusa and experienced back and leg pain? I already have 2 herniated discs but it seems that since I started the medicine it has increased my pain and started pain in my legs. ## Joint and muscle aches can be a normal side effect of this medication, according to FDA reports, you may also experience nausea, dizziness, and headache. Has there been any change? Are you on any other medications? ## Not any new meds other than Epclusa. Dr. put me Gabapentin which has helped with the leg pain. ## About 2.5 to 3 weeks after starting epclusa I've had back pain and leg pain its worsened and am down to my last 2 days. I'm hoping my pain is contributed to the epclusa and was wondering how soon after treatment will the pain go away ## No new medicines. Pain in legs started ...

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Did 10 weeks of harvoni and ribasphere had to quit ribasphere at 9.5 weeks of 12 due to possible stroke symptoms and now 2 weeks off the meds experienced heart attack symptoms. Tired still and neausea off and on pellet like stools with heavy mucous all the while drinking tons of water mmy ribasphere was upped from 3a day to 5 a day at week 4 why? They say cause it was to keep the hemocrit v levels even I say it caused all these symptom s 3 weeks after stoppingall medicines. My eyes so blurry I cant concentrate on tv or the internet or read the paper the ## There is a warning that if you experience vision problems while taking Ribasphere, you should inform your doctor immediately. Ref: Ribasphere Information Typical side effects may include nausea, chills, headache, and feeling weak, and...

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I have take Harvoni for 6 months. Along with xanax and sometimes ambein to help sleep. I have been off two days and my fatigue is worse. I can not sleep. My mind is overtime. I was really looking forward to stopping all drugs after 6 months. Now I am in a depression not sure why. I cry for no reason. And I work in Public Relations, Event planning. Can't focus to do job. My mind knows what need to say. But does not come out right. I have taken to my bedroom. For comfort and prayer. Anyone else feel like this? Thanks ## Hi I have similar problems headache wide awake constipation fatigue, good news is viral free,I was told it could be upwards to 6 months to clear drug so a slow detox is in play with exercise a key to this a hard but a must for many reasons being tissue is a storage pla...

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Beginning January I completed 3 months of Epclusa, n now am every day dealing with foot,ankle and lower leg swelling. What has happened, am adjusting my diet to minimize effects of that n nausea; it was into the third month that these conditions began to settle in! so far there has been no knowledgeable feed back, like the specialist are only guessing; this is very disconcerting to me. ## I don't know if you know about the lawyers in Texas helping people on harvoni, but epclusa has half of the same medicine in it. They told me to get more people to call. Their name is George Fleming 1-713-621-7944. I took it a year and a half ago and I'm still messed up with my nervous system. Please call them!!!! This may be our only chance. Spread the word to more epclusa patients. ## Hi been ...

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I am on 24 weeks treatment I did 1 month and a half with harvoni and ribavirin stop the ribavirin and my liver enzymes Alt and Ast were up in my blood works then on my next blood works 14 weeks into treatment my enzymes went down again. I don't know if it was the virus resistance. ## Ribavirin has been known to affect the liver, and to cause side effects, including elevated liver enzymes on blood work, so it may have just been due to taking it. Ref: Medline Plus Ribavirin Other side effects may include nausea, insomnia, memory loss, diarrhea, and cough, according to FDA reports. Did your doctor feel there was any reason to be concerned? Harvoni can also cause side effects, such as nausea, muscle pain, dizziness, irritability, headache, and tiredness. Ref: Medline Plus Harvoni

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As I read the side effects I find myself getting more and more annoyed at big pharma. If you google Gilead and litigation you will see that this drug was pushed though trials and sort of held back side effects. In addition that's not really safe because the people that participated in the trials were very ill. My hepatitis was fortunately stable, as i posted on another thread 2 wks into this and i am going to the doc tomorrow and saying OFF! Of course they cover their arse and do the labs to see if its not anything else. My face is pasty white, i discussed the mood swings i am like a black box warning but alive. its taking every bit of energy to keep my emotions in tact. I DRINK a Gal easy of water, its not the water, its the freaking drug! I think they are either dismissive or don...

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Hi my wife has just started harvoni - about 9 days or so now - and she is getting swelling in left leg and also feels like there is pressure in her head. Anyone else have anything similar? Thanks ## Hello, Chris! How is your wife doing? Has there been any change? It has been known to cause headaches, according to the FDA, but the edema is unusual. Other typical side effects may include nausea, diarrhea and insomnia. Is the only medication that she is on? She should likely have this checked out by her doctor. ## Hello. I took Harvoni for 12 weeks, 6 months ago. I had the weird pressure in my head also. It continued on and off thru treatment. It was a pressureb headache. It went away soon as I finished the meds. I also have swelling in both my feet and ankles. Its related to me being a 55...

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I just looked up this info to see if anyone else was having this post symptom of swelling of hands but there aren't any which is good . My treatment went great. I'm fine . I'm 63 in good shape because I'm in the gym from coaching basketball. No side affeces during treatment I took mine at 6:00 am every day with plenty of water and for three months drunk more water. About to see doctor for post treatment appointment one month after completing meds . ## I'm sorry, but you forgot to list the treatment you underwent. What medication was used, and what condition was being treated? Many medications can cause edema, according to FDA reports, including blood pressure medications, some antidepressants, some anxiety medications, and etc. Far too many to list each one individua...

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In need of an answer asap. Start" harvoni treatment this Tuesday." Doctor is( taking away Digoxin for heart and changing it to Metoprolol Succinate ER-did take metoprolol tartrate for B/P.) He also wants me to take (liquid Gabapentin in place of my xanax that I have taken for 16 years. Was taking 3-4, 2mg tablets of xanax daily, then I cut back to 1 mg tablets 3-4 tabs daily, which I cut back myself and feel I am ok, and do not want withdrawals, and have to go to work-no choice but also need the Harvoni. Why all of the changes? I don't mind the Metoprolol Succ ER change, but the xanax, yes. ## I checked several databases, and didn't find any interactions listed between Harvoni, and Xanax, however, it is always possible that your doctor is aware of some issue that has not...

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1- kinds of positive effectiveness on pulmonary diseases 2-side effects ## I'm sorry, I am having trouble finding information on this. Where you referring to the product manufactured by NeilMed that is a sinus rinse called NasaFlo? If so, it is just a saline rinse to help clear the sinuses. ## Hi ,I am on my 3rd prescription of anti biotics for what started as small skin irradiation on shin,it's been 14 days now ,it has doubled in size plus infected my dr thinks it's improving I hope so,I also have copd onset asthma,emphasemia I'm 67yrs old ,finished Epclusa treatment 2 yrs ago,IV read recently that flixotide (containing fluticasone proprionate) can cause skin infection s that can take many mths to heal,my dr has me on flixotide twice a day, in my opinion 3 scripts antib...

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