Nuvigil Side Effects
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I'm having severe side effects from nuvigil. Muscle and joint pain with numbness and tingling down my arms.

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Re: Bob B (# 167) Expand Referenced Message

Hi Bob.....you kill me how you write......funny, but brutally honest!! I just started taking nuvigil and the last thing I want to loose is my sex life.....with numb arms! Sounds Horrible... Thanks for the info....Beverly from Colorado.

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213

I took Armodafinil (Nuvigil) 75mg for three days and everyday I was experiencing itching in my body. I'm badly in need of taking this medicine for daytime sleepiness. Can I take an antihistamine medicine for relief from the itching? Or what are the alternative ways to treat it?

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212

For chronic fatigue I valiantly tried to make Nuvigil work for me on & off for years and end up going right back to Generic provigil. 2-3 pills in of Nuvigil. I start to feel it coming on & get then the stomach spasms from Hell begin then Fever body aches, Ringing in my ears. This drug is in need of a serious over haul in my opinion. it’s truly a waste to have a potentially wonderful life changing medication not do what it’s designed fully to do.

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211

I've taken Nuvigil for years along w/ meds for RA, thyroid, fibromyalgia, HPN, etc. My insurance denied coverage repeatedly for weeks recently. I contracted Influenza A & pneumonia during this time, plus experienced withdrawal. I began Nuvigil for the past 2 days again and had terrible reactions within 6 hrs.

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210

My head felt like there was a hamster on speed running around on a wheel it was horrible

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209

From my experience with insurance, the most likely reason they will not pay for it is because treatment of MS would be an "off label use," so insurance companies want documented proof that MS specific treatments have been ineffecrive for you. I have Narcolepsy and Shift Work Disorder and my insurance still would not cover Nuvigil until I had tried Provigil as it is cheaper.

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208

I am also on Nuvigil for Narcolepsy and Shift Work Disorder and experience similar side effects. From what I have read and can understand, Nuvigil blocks the reuptake of dopamine creating extra-cellular levels, however it does not increase dopamine production. Because of this method of action, Nuvigil can become ineffective and have increased side effects after just a few days. Dopamine is often the nurotransmitter related to our "pleasure center," increasing feelings of wakefulness, euphoria and even pain relief. So when the initial boost of extra-cellular levels of Dopamine decline, we begin to experience pain, depressed mood and reduced wakefulness. Nausea, headaches and muscle/joint pain are listed as common side effects of Nuvigil. Increased anxiety and heart rate are also common which could explain the feeling of irregular breathing. The best advice I have come across to reduce these symptoms is to only take the medication when absolutely necessary. I choose to have my "off days" when I am off work. Unfortunately, on these days, I can barely function and still experience the negative effects which makes life very difficult as I am a single mom. I have also read of people cycling their Nuvigil where they take it for two weeks, one week off, one week on and two weeks off. For me, that does not seem like a feasible option so you would need to take into account your own life style, schedule, etc. and discuss it with your doctor. I hope this helps.

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207

Went from adderall to nuvigil. The doctors are getting BIG kickbacks for this drug. It's a $900 p/m drug... So they are going to fight to keep you on it. I had an allergic reaction on the darn stuff, my former doc KNEW it was a huge issue and took me off immediately. It's been 4 years. I told my doc I started breaking out itching all over that only got worse and never stopped Even 12+ hours after taking the tablet. He just said to lower the dose and keep trying to "make it work"-- now I'm worried because I'm reading about s.j.s and all these HUGE warnings about itching with this drug... I'll be looking for a different doctor Monday morning.

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206

I had horrible side effects I felt like I was on speed couldn't sleep at night confused and didn't want to continue living on that way I quit taking that but it took a week before I began to feel normal again Took me a while before I figured out what was making me go crazy

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205

Woa stop taking it! Sounds like a heart attack or stroke.

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204

I have the exact same issues. I'm only 24. I get symptoms like if I lye in bed and stay completely still I loose all feeling in my arms and legs and if I move they start to sting. Also I have the same issue with the porn and it takes an extreme amount of exertion to climax. Also I can't stop knashing my teeth and I have little feel in my mouth. Sometimes I will get flu like symptoms and my lips swell and my veins are bulging my nostrils become sore and it always feels like there's something in my nose. When I am finally able to fall asleep in have extremely vivid dreams this is actually one of the pluses they very strange but enjoyable but about 35% of them are terrifying, I don't mind this since before the medication I never could remember my dream. I also start to have auditory hallucinations and minor visual hallucinations after about 6 hrs into the day the walls look like there moving and it looks like a swarm of gnats are under my door and I think I hear people walking around the house or talking but nobody is home and I will think I hear sirens constantly but they never get closer.

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203

Ive had shortness of breath for 6 months on nuvigil and ggonna stop it immediately. Hope my breathing gets bette

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202

Are you on the generic version? I have been having all sorts of stomach issues with it.

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201

Yes I do. But I am experiencing nausea, bloating, and pain just under my rib cage. I'm on the 250mg dose. May try halfing it.

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200

My 2nd day on 250mg Nuvigil. I've chewed a hole in my lower lip and my heart is racing.
I've accepted that I'll be up all night but this is not a med I want to take.

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199

I started taking 200mg if Nuvigil this morning at 9:15. Felt pretty good all day. Thus evening about 12 hours after taking it started feeling nauseous, having chest pains, chest feels heavy and tingling in my body. Has anyone else had these symptoms after only one dose of this stuff. Do I need to be checked out or will these symptoms subside as the night goes on? Def calling my dr Monday morning. Not taking any of this tomorrow either.

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198

Im going through the same feeling im bloated and stomach is burning and bubling

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197

I have been getting neck and shoulder pain. Along with ears and head.

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196

Anger, nervousness, easily angered, flies off the handle, very emotional - cries easily.

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195

Let me just say that i never suspected that the symptoms i was having was the nuvigil because of how it helped so much in the beginning! Extreme joint pain ...extra tiredness ... day 2 of not taking it and felt almost 100% better... went through so many test and dropped a couple other meds before i finally decided to not take the nuvigil. ..i have narcolepsy and am prescribed 250mg ... i have nothing bad to say about this drug because for the last 7 months it was a life saver... but now i must seek a diffent way to stay awake!

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