Zydus 10mg Oxycodone Underdosed? (Page 6)
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Hello all. For the last 6 months, i've been prescribed various meds/treatments/pain meds for severe head pressure and neck pain. I had to stop taking any form of Hydrocodone because it makes my skin breakout in open sores (gross, i know). On May 6th, my PCP prescribed me Oxycodone 10mg 4times daily with great results and it made me very fuctional. He gave me another script for the same medication and when i went to the pharmacy, they filled it and when i got home, i notices the tablets/drug company was different. Well, was i in for a suprise. The new generics my pharmacy had were made by Zydus Pharmaceuticals and are imported from India? Well, to say the least, i've been taking almost twice my dosage to get the same effect. There's no way on earth that my tolerance doubled in less than a day! Now, my PCP thinks i'm trying to get more pills, and the pharmacy thinks i'm crazy. The first prescrption i got the 10mg oxycodone from this manufacturer: KVK Tech Inc (pink and "k 56" imprint on them. And they worked fabulous. These Zydus ones seem wayyyy underdosed as i'm taking around 5-6 tabs compared to 4 tabs of the KVK Tech brand. Any info/advice is greatly appreciated!

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I absolutely agree with you--The KVK tablets are sooooo much netter--The zydus were like placebos--so I struggled for one month with them, and now I check my pharmacy before I fill my RX's to see what pharmaceuical company is prescribing them. It made such a difference. I just refilled my RX with KVK and I am so pleased with the difference after a month on the zydus--always do your research--Good luck!

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Hi, I am a RN and fractured my hip and developed hip bursitis -- I was taking waaaaay too many oxycodones for pain and my doc thought I had accodemated to them and I went on hydrocodone and was miserable for a month. I went back on my 10 mg of oxycodone and got no pain relief so I googled 'Zydus oxycodone' and was amazed at all the issues with their drugs, I called the pharmacy and of course they could not take my bottle of meds minus the 4 I took back but they did tell me to get my doc to write for the 5 mg tabs-2 q 4-6 hrs as needed, which he did. I turned the pills that did not work into him to be destroyed and filled out the FDA forms so they can check into the issue. Hope this helps

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Thank you Verwon! I'm just terrified about all this because the long holiday weekend is coming up and my PCP wis as hard to get ahold of than the President. These Zydus Oxy 10's are no way the same quality/dosage as the other brand, and i spoke with my PCP and pharmacist about this today and they said that this Rite Aid only has the Zydus brand available at this time. I tried today to convince my PCP to switch my current oxy 10's to a "brand name" and i'll spend the extra few dollars. Not a chance. He thinks my tolerance is growing, and thats complete BULLSH*T, as i've been fine on the other brand at the same dosage everyday for the past two weeks. Please everyone, tell me what i should do, as the anxiety is seriously overriding me about all this, and its making my pain even worse. Please help me, i am truly in need of what to do. Should i try a methadone clinic? Thats how disgusted i am with my PCP/Neurologist. They never return calls and when Friday comes around, i'm stuck, especially now since its Memorial Day weekend. This is absurd behavior on their part. Thanks for any help all of you can give me!

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There can be fluctuations from one generic to another, so the one from Zydus may be slightly lower in the amount of the active ingredient and it just may not work for you as well as the ones from KVK Tech.

Learn more Oxycodone details here.

However, as you've discovered there are issues with convincing the pharmacy and your doctor of the problem.

Next time, you may want to use a different pharmacy, if your current one won't listen and order others in for you.

As to your doctor, I'm really not sure what you can do there, other than be completely honest with them. I wish I had some other idea for you, but I don't. Prescribing it 4 times a day is really the maximum he can do.

Does anyone else have any advice they can offer?

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