Topamax Is Different Over Time

I first started on Topamax in 1999; no titration (which was hell) at something like 150 mg twice a day. It was wonderful, a miracle - for my Bipolar. I stayed on it for over 10 years, only going off because of new a Dr, new insurance. Then, last year in 2015 I started back on it. I can't even tolerate 100 mg A DAY in 2 doses. I become a raging B****! (Or cry in the middle of a crowded mall). I stopped it for months, then tried again. 25 mg twice a day did nothing. The Bipolar in me rather enjoys being a b**** except every body I know; all my family is pissed at me. People really need to watch for meds like this - you never know what'll happen.

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It isn't the medication that's different, it's you! Our bodies change as we age, and a medication that worked great for us years ago, might not work, when we try it, again.

For example, I successfully took Zoloft for 6 or 7 years, then stopped… and later, when having some anxiety, my cardiologist suggested I try it again, about 4 years after having stopped it… and it was horrible. I didn't feel suicidal, but within a few doses, I found myself wishing I were dead and that everything was just over. I ended up having to switch to Prozac, which has worked wonders.

As reported by the FDA, bad reactions to antidepressants may also include suicidal ideation, rebound anxiety, depression and diarrhea.

Is there anything else I can help with?

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