Teva Lorazepam Reviews (Page 16)

I'm seeking insights and reviews on Teva Lorazepam and its comparison with Leading Pharma's version. There's a notable divide in user experiences. Some report Leading Pharma Lorazepam as being less effective or having no effect, possibly due to variations in the active ingredient, leading to side effects or adverse reactions in certain cases.

While there are those who recommend Teva Lorazepam for its efficacy, others find Leading Pharma's version more suitable. Unfortunately, I haven't had the opportunity to try Teva Lorazepam since it's not available in my area – no local pharmacies dispense it.

My experience with other brands, post the discontinuation of Qualitest, hasn't been successful in finding a comparable alternative. I'm particularly interested in understanding how Teva Lorazepam and Leading Pharma's lorazepam differ in terms of effectiveness and user satisfaction.

If you've had experiences with either or both of these medications, your reviews would be incredibly valuable. Any insights into their efficacy, side effects, or overall satisfaction would greatly help me and others in our decisions.

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Re: Richard h (# 292)

Richard, I wanted to apologize for being hard you last month. I don't want to make excuses. Some of us are really being put through the mill here. I let my thoughts run out on you and for that I'm sorry. Tread lightly Rich if that makes sense to you. I'm a old dog like you. I've been doing this for sometime. Peace!

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Re: Jibbs55 (# 300)

that is a very good observation on your part. I have thought the same myself but i believe instead of getting rid of them you will have to see a psychiatrist to get them ...... like how you would have to go to pain management to get opioids. And i also think the black box warning and the fda admitting these drugs are really hard to come off of and withdrawal can last for many month if not years has scared doctors put of wanting to prescribe them and taking existing patients off of them.... But pharmaceutical companies are way to money hungry to get rid of benzo or opioids. Even when you look at lawsuits say like prude pharma they settled for 6 billion that's just a drop in the bucket of what they made...... they most likely made like 80 billion off the oxy if not more over the years. Just my 2 cents anyways

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Re: gsrmike98 (# 299)

Yes, I have tolerance withdrawal even before this change. It's interesting you found it to be stronger. You don't know what lot you are on by chance do you? My pharmacy started printing the lot numbers on the bottles. Mine is 100023425 exp 5/23.

I wonder if it could be a bad batch.

I can't updose. My psychiatric provider said that when I first started seeing them. I should have tapered when I was feeling better a while ago and thought of it but they were against it at the time. I'm not sure if they realize that over time you do go into withdrawal staying at the same dose.

There's a possibility my reaction is something else that's a coincidence. I'm not sure. I have a lot of stressors in my life, but I haven't been this bad off any time I can remember.

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Re: Marcus (# 303)

No sorry, no lot number on my bottles or on my little paper on the bag, it just says teva usa. i do have the ndc number 0093-3425-05 if that helps.... and ya sorry to hear that about your Doctor ..... 98 percent are clueless about tolerance, withdrawal, or even how to taper a patient off....... Ashton Manual is the way to go. No more than 10 percent of your dose should be cut per month, that's a minimum. Taper of 10 months but you can go slower..... there is direct taper, cross taper, and liquid titration tapers as well. Dr Ashton was all about the cross over taper to Valium because it has the longest half life ... so not intermittent withdrawals to deal with .... Plus there's all the peripheral benzo receptors all over our entire body with makes the withdrawal like living through being tortured 24/7 for months of even years.... The peripheral receptors are on our lung, heart, kidneys, stomach, blood vessels, immune system, and even the cells' energy supply called mitochondria.

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Re: Linda (# 293)

Make sure to contact Teva and file a complaint.

When they discontinued Actavis clonazepam (klonopin), enough people complained to their customer service and they brought it back. There was even an online petition to bring it back.

I have e-mailed them, but may need to start a petition.

I have only a very few of the old Watson and as a daily user for over 20 years, it has been horrid switching to the in-house Teva brand. I saw some people felt more sedated, but for me it's been like a rapid withdrawal, and I have lost nearly all functioning. I was having to take more of another medication to try to make up for it, but it wasn't helping. And then yesterday for two of my doses I took a Watson tablet at each, and it just felt . . . I can't even describe the difference. It's not a "high" or anything like that--it never has been. It's just being able to to back to doing normal things.

Surprisingly my insurance agreed to cover the brand name Ativan, but to be honest it was not as good as Watson. The brand name is not the original and hasn't been for a long time. I was on the original brand name which I think was made in Pennsylvania by Wyeth. Then it got bought out and the production at least for a while was in Germany, and that version was also pretty good. The most recent version I had was made in Canada (same packaging so you wouldn't know unless you saw the manufacturer's box), and it was not as effective. But I am hoping it will be effective enough. You could always try asking your doctor for a prior auth--in my case I surprisingly didn't need one, which I was told is rare.

But definitely contact Teva:

[email protected]

They did this exact same thing with Klonopin, and they did eventually bring back the original formula. I am not sure if I am allowed to post links here, but you can Google Teva klonopin petition.

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I was prescribed Leading brand. Does not work. Like taking a sugar pill. I am taking 1mg Teva nothing but fall asleep. Does not take away anxiety. I was taking Watson and it worked great. They are now Allergen in Ireland. Sigh.

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Re: Verwon (# 1)

Look up lorazepam drug color, scored, numbers it will show the manufacturer.

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I wished my doctor was as kind as it seems many of yours are. The last two I've had from the military have rode me like a donkey. When I tell mine that the brands that don't work for me they've both told me we can't write you another script. Also they won't write outside of the base. The VA is the same way. Plus they won't board approve the brand that works for us Vets. I had a Pdoc for years that worked with me through any struggle I might have ran into. Pharmacist will tell you that they won't help you change you've got to take what we have. Both the doctors and pharmacist will say it's against the law to write a new script until your out. They actually are harder on us Vets then the Pdoc. That includes the techs. There's no compassion at all. It's not just in my area it's across the board military wise. My brother is a combat vet that gets ripped just for being on 2mgs of Klonopin. Here's a heads up for anyone that might fit Bausch Health patient assistant program. Google the words I just put above and see if you fit their requirements to get brand name from them for free. I had it for awhile but my new Pdoc stripped it from me to keep everyone in house for the military. But if you make less money then their requirements you should be about to get it approved through your doctor and them.There was word they were going to discontinue brand Ativan with this program. Just check and see if they did. Your not out anything either way. Hope that might help some of you.

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Re: Jibbs55 (# 308)

This makes me wonder if we're all getting the same lorazepam ? Base on where we live in the US. I know for a fact that the inactive ingredients are 100 percent the same..... when u look up ndc numbers it takes you to an fda government site where u can look at stuff like that .....

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Re: Marcus (# 305)

Yes I also experienced the same thing with teva. today I also filed a complaint at [email protected] and they replied to it. Hopefully with so many complaints, they can understand

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Re: Lex (# 310)

I'm sorry you're going through the same. Thank you for writing them.

I'm back on the name brand for now. I've only taken once dose so far, and I'll try to be optimistic, but it hasn't been great so far. It had worked well for me before, but they've moved production many times (now in Canada), and it seems like the rest now.

I start to wonder if there could be an active pharmaceutical ingredient (API) manufacturer that left the market. There's not much to any of these tablets. The API and some fillers. I've read stories from FDA enforcement reports of how the APIs come from all over, and the companies are supposed to get COAs (certificates of analysis) when the APIs arrive, but in FDA inspections sometimes they haven't or it's been after the fact. So whoever actually makes the "lorazepam" in lorazepam is a mystery. I asked in my e-mail if Teva switched API suppliers, and they said that was proprietary information. The main problem IMO is that they only test for bioequivalence—looking for plasma levels to be similar to the original drug when given to healthy volunteers--meaning don't have the disease the medicine is taken for, They never actually look at its effect and whether it works. And I don't think they even have to do bioequivalence testing when they change plants, etc. I think it's just with the first ANDA application in a relatively few number of people. It's very difficult to tell from the FDA Drug Database, which isn't really populated and kept up to date, which ANDA Teva is now using, as they've had lorazepam marketed many times. I'm wondering if someone will buy the old Watson manufacturing site? Or maybe they'll send them to a new market abroad. I'm thinking I may have to switch benzodiazepines. This has happened so many times now with Ativan. I see that the brand name of Xanax is reasonably priced and seems to have been the same manufacturer over a long period of time. I've been scared off by everything I've heard about Xanax, and I'm guessing my doctor probably has been too. I just don't know think there is a good lorazepam left.

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Re: Marcus (# 311)

Not sure if you tried Aurobindo yet but it to me works the best compared to even the so-called brand name Ativan. I can't remember if it was you that had swallowing problems after taken it. If you haven't tried it and brand doesn't pan out for you look into it. I'm still struggling to understand how many of you have pdoc's or primary care docs writing you guys new scripts if one doesn't work. Probably said this before all of us are on a prescription drug monitoring system since it's a controlled substance. Everywhere you get your lorazepam each pharmacy can do a check on you. Military does it each time I have a new script written. If my Pdoc finds that I had a script fill other then him it wouldn't be pretty. Wish you well with the brand.

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Re: Jibbs55 (# 312)

Hi,

Thanks very much. I tried Aurobindo a long time ago, and I might try it again as the brand is not what it used to be at all. I can't describe it, but the times I took my last few Watson tablets, I just felt normal in my head. And I've been so uncomfortable since stopping them.

My doctor would never prescribe a new script until one runs out. The timing was such that it was time to refill when I got the name-brand, and she even purposefully did it for only two weeks in case it doesn't work out. You can also ask the pharmacy to dispense less than the full amount. I'm in the US too. I know how much trouble people give you about benzos—the same industry that caused the trouble. I've asked before about getting gabapentin to help withdraw from the benzos, and my doctor won't even prescribe that because it's now a controlled substance in my state. She'll only keep me at the dose I've been on, which has been for many, many years, so I'm tolerant to it--even before the fiasco with switching brands.

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Since starting the brand name, I've had what other people have describe of falling asleep and not having anxiety relief.

For me, when I stopped taking Watson, my symptoms were bad and included insomnia and agitation.

I've built up so much sleep-debt that I have exhaustion such that when I take the medicine, it's just enough that I then conk out, and then I wake in a night sweat with a racing heart after the medicine's worn off.

I know there's medicine in it. It's just not the same feeling or enough of it or something.

I take 1 mg 3x per day. And because I've not been sleeping at night, when I take the doses in the daytime is when I fall asleep. But just for very fitful short bursts. I'm now sleeping 2 or 3 times in the daytime. It's crazy. I had no problems before being awake all day taking the medicine 3x a day and then going to bed a few hours after the last dose. I think I'm in so much withdrawal that my body will only let me sleep right after the dose now. It's like it takes just enough of the withdrawal away. But it's supposedly exactly the same amount and the same medicine I'm taking. Yet I feel like I'm in a funhouse.

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Trying to find a brand I have tried, and came across Loreev XR which is a once-daily lorazepam product. I'm wondering if anyone has tried it?

https:/­/­www.loreevxr.com/­

It looks like they use some chemicals to keep it from dissolving as fast--not the capsule itself--as it says it can be sprinkled on applesauce.

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Re: Marcus (# 315)

Interesting. I just looked it up, was released late last year. Basically like Xanax XR, once a day time released dose. Retail price is around $400 for 30 which is a heck of a lot less than Bauch's brand Ativan so hopefully easier to get insurance approval. Only bummer for those of us who take more than 3mg/day is we'd have to take 2 capsules in the morning which is easy enough to physically do but insurance companies often balk at approving more than 1 dose/day of XR drugs as it's supposed to be a one pill product.

If anyone has tried it or plans to pls post your experience.

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I've done some more research, trying to find out how generics are tested and so forth.

Even though the new Teva lorazepam has a new NDC, new manufacturing site, and new imprint, it stills uses ANDA (approved new drug application) 072927, which is from Watson Laboratories from 1991.

As far as I can tell, a company only has to prove bioequivalence when they apply to make a drug. That means over the many manufacturing site changes it's still assumed to work the same as it did when it was first tested. I assume the inactive ingredients must have changed since 1991 as well.

I am trying to find more out about this.

The resources I've used are the FDA Orange Book, FDA Drugs@FDA database, and FDA NDC Directory. Each has some information the other does not. It's extremely confusing because Watson (the company that once existed) is still to this day listed as the manufacturer of three different lorazepam products in the three strengths.

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Re: Richard h (# 292)

Richard, hope you come back to the group. Always appreciated your experience and your insights. Curious to hear your thoughts on Teva. Had taken it for a few days and then finished the Aurobindo I had left. Been back on Teva 2 days and mixed results so far, always takes me several days to adjust. Takes longer to kick in, been having headaches, sleep has actually been better, mostly effective for anxiety.

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Re: Marcus (# 317)

i looked into all as well marcus teva did not change the inactive ingredients watson/ actavis and teva all have the same inactive ingredients you can look them up by ndc numbers which takes you to a fda goverment site so on there the they both list the same i just think the switch was to much for you to handle since you were in tolerance withdrawal when it happened

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Re: gsrmike98 (# 319)

sorry but i have been on lorazepam for over 30 years, and this idea that a product is the same just doesnt fly. Back around 2014 sandoz bought out actavis lorazepam and and started to make their own lorazepam. I was unaware that there was a new owner in sandoz. I took a tablet the first day and was up all night. It took 3 days to realize that it was the medication not me that had the problem. I contacted both actavis and sandoz and they both assured me it was the same product. No it wasn't, for if it was it would have the same effect on people. Sandoz has shut down the lorazepam production at least once because people realize their product is trash. The first 15 years of this medication their were no issues that I had heard of but once companies started buying other companies lorazepam, the issues started. One thing I find interesting is that some of the people writing on this column have said that they thought that mylan's lorazepam was the best, but no one's asking why they quit making the product.

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