Switching From Zoloft To Brintellix (Page 2) (Top voted first)

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Today my doc told me to reduce my Zoloft from 100 MG to 50 MG for the next 6 days. On the 7th day I will begin 10 MG of Brintellix in the morning with breakfast. If I experience any sleepiness I should start taking it in the evening.
My follow up visit is scheduled for June 29.
I have tried many amtidepressants over the years with minimal to moderate success. I hope this is magic bullet.

40 Replies (2 Pages)

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15

I'm on 200 mg of Wellbutrin SR and 400 Mg Lamictal. This combo had pooped out on me. I have no sense of joy, am up and down and have apathy. Pdoc wants me to try brintellix. It's sitting here on my nightstand and I am very frightened after reading some of the posts on here. I've been waiting to try it on the weekend so I'll be starting Saturday. Price said I could take it with the Wellbutrin, even though there are issues with drug interaction. Our I hope this med will help me. I am super anxious in starting it though. Anyone else here on brintellix/Wellbutrin/Lamictal combo?

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16

How long did it take to feel positive effects of Brintellix?

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20

Or keeps one person from having devastating side effects! I seriously was afraid I was "on the way out". We all realize ANY drug can have all sorts of outcomes depending on the individual taking it.

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22

Hey Dazydo, how long were you on the 15mg for?? The drowsiness you may have felt might have been a temporary side effect, were you patient on the 15mg?

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23

Had the same experience ): hope you're doing well now

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25

i bern taking brintellix about a month and i have extreme sweating and nausea even after i eat but i take it at night will daytime make a difference

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28

I have been weaning off 150 mg of zoloft to 10 mg of trintellix. I go to pick up trintellix & insurance will not cover it. For almost $400 a month, it must be a miracle drug. Now what do I do???

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29

Ask you Dr. There is a coupon with a code the pharmacy will save to your file!

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30

I was on 200mg zoloft. It just stopped working. Kept taking and when script out went right into taking 10mg brintellix. I have had the worst withdrawal symptoms- ringing in ears, equilibrium off, and now vomiting. Started taking 20mg two nights ago but still vomiting. Going to doc in AM. I suspect dose isn't high enough.

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31

I've tried everything for many years. The worst for me was Effexor- I couldn't handle it. I know we are all different. I've been on Zoloft anywhere from 25 to 50 to 100 to 150. It did nothing. Every time I decrease, I get the "shake shakes" luckily not any brain zaps. The doctor lowered my dose to 25 mg Zoloft for 3 days before taking the Brintellix. Im praying it helps. I have no energy at all at am not motivated to do anything. Great life! No suicidal thoughts ever!

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32

Well, Day 1 of Brintellix and so far so good. Still have the shake shakes going on but they are manageable. Staying positive

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34

Wondering if trintellix is causing numbness in hands and feet. I have not had this problem with my diabetes before

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35

I'm on the same meds and prescriptions as you and I had terrible effects with the brintillix 5mg. I felt like I was more hostile, severe migraines and my allergies where really bad. I too am waiting to see the doctor and and just on 100mg. of seroquel at night to sleep and valium low doses for my anxiety. I really don't know what's left for me to try.
Hope you have more success than me.
Good luck Fayzah

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37

Re: Nicole (# 30) Expand Referenced Message

This sounds a lot like what I've been experiencing. I stopped 150 mg. of Zoloft (tapered over 5 days) and then started Trintellix. Exactly 3 weeks on Trintellix and I was very light headed and overall just not myself. I gave the Trintellix about 6 weeks and still didn't feel well so I tapered off. I was then put back on Zoloft (25 mg.). I'm currently on 50 mg. of Zoloft and still feel terrible. How long did it take you to recover? I'm concerned, as it's been 6 weeks since I started feeling bad and I continue to all day every day. :(

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38

its been couple years wondering if it helped u any?

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39

Your doctor knows best. There have been studies that show how people best react when switching medications.

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40

I just switched from cipralex 10mg to trintellix 10mg 5 days ago. I was always feeling tired with cipralex so wanted to try something else. So far Trintellix is working realy well. no side effects although I feel a bit of withdrawal from cipralex (I’ve weaned down from 20mg before so recognize the feeling). I’m trying this for the month and will decide from there is this is a better antidepressant for me. I’m pretty optimistic here at end of day 5. Good luck to all working on getting a better handle on depression, keep going forward, you’re not alone!

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36

I am now off Trintellix as they call it here. Not because it wasn't working or any side effects but because when I went to pick it up the pharmacy said "That will be $800 please." As it turns out, I had hit my coverage gap in Medicare and 3 months worth went back to normal pricing of $266 a month. For ME, and I realize EVERYONE'S chemical composition is different and they react differently to meds, but for me it was not a miracle drug. In fact I could tell no difference in it and the $4 formulary drugs at WalMart. Sometimes Big Pharma is not the answer.

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1

don't do it! i have been on ssri meds for over 20 yrs. dr started me on trintellix 3 wks ago. have not been out of the house since then due to nausea, vomiting, diarrhea, fatigue and more. Now trying to wean off of it but dr and pharmacist are not sure how to proceed with this. i am also imsulin dependent diabetic andy sugars are erratic. terrifying drug at least for me.

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14

DO NOT TAKE THIS ANTIDEPRESSANT AT ALL. IT MADE ME VERY SICK, VOMITING, HEADACHES, PHYSICALLY ILL. I TOOK IT FOR A WEEK. ASK FOR SOME OTHER ANTIDEPRESSANT. BAD DRUG!!!!

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