Prolia Side Effects (Page 25) (Top voted first)

I would like to know of any side effects others may have experienced after receiving Prolia infusions. Up to now I have none.

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Re: Gloria (# 2615)
Most certainly NOT. The main ingredient in Prolia and it's twin are the same. The twin is used on breast cancer patients when it has spread to the bone so they are getting it for the same reason we do.....build up bone mass! Chemo and radiation for a cancer can cause severe bone loss -- much worse than osteoporosis. Prolia has to be the worst drug ever made but it could be beneficial to those that have their spine totally falling apart into little pieces. To me it seems to be a lose-lose situation. Everyone, please get this fact into your minds. Do more real research instead of believing what is false. I even thought that in the beginning until I really researched the matter. Be well~Pood

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Re: sal (# 2618)

Didn't we all. The only good for me was the fact that I've educated my daughters to question everything they put in their bodies and DO THEIR HOMEWORK before they make any decision!!

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I think I am experiencing problems from two years of taking it. Starting over a year ago, I noticed excess saliva coming up under my bottom lip. They try to say I have GERD but I do not. It's not like GERD with sore throat or cough or any stomach pain. It's ALL in my mouth. I got an infection in my mouth as well and was getting lesions on my tongue from time to time. My mouth gets a bit dry and usually though, it gets too much saliva in it. It can taste different ways, salty, yucky, and maybe what acid tastes like. sometimes I feel like I cannot swallow. No doctor can treat me. Their acid reflux pills do not work. I finally went to a neuro clinic . I was noticing also some imbalance, which is a less common side effect of Prolia. The neuro clinic says I am off balance. Finally, I have tendonitis now and my shoulder which was healing and feeling much better before I started Prolia is beginning to have more pain again. This is NOT normal and two doctors said something like this: "I have never heard your story."

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Re: Lizzie (# 2635)

Regarding pain in shoulder and toes: It has been 19 months since my last shot; yet my toes and shoulders are still painful and even deformed. I suspect that arthritis was there, but Prolia caused it to manifest. Clearly, this is not going to resolve. P.s. my ankles too. This is a highly toxic drug and should not be prescribed so easily.

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I lost all of my top teeth and had implants. Now I have a very loose bottom tooth. Very depressing. Never ever take Prolia if you want to keep your teeth...

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Re: Norma (# 2645)

There are a very few instances when Prolia is indicated such as bone cancer that is a metastasis, or a VERY high risk because of long term steroids, but they are few and far between in comparison to the number of people it has been prescribed. Unless one falls into the category for it original intent DO NOT TAKE IT !!!!! It is not safe !

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Marion (# 2496) --

Question here in almost October now. Did your nerve Doc do any testing on you like a Nerve Conduction Velocity and EMG? Often times the burning sensation can be from meds but at other times it happens to us because of our age and what we do or do not eat food wise. I had a horrible burning sensation all over whole body from using consecutively two different types of blood pressure meds at very low doses. Finally went to the ER and the Doc there dropped me into a third category of blood pressure meds on pediatric dose and the horrible burning stopped after a few weeks. Also had to stay in ER for hours for my BP to come back from 66/44. Finally let me go when the bottom got to 77 hours later. It had to make it's way out of my blood and liver and then I was free. I wanted it gone yesterday. It would seem that there are those of us that are much more sensitive to drugs than others. I would request the two nerve studies to make sure it is the med and not any other condition. They are basically painless. To your best~Pood

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Re: sal (# 2646)

I do know that Amgen conducted the study of Prolia in France in this year. That seems to me to be the fox watching the chickens. How flawed could that study possibly be! On another site were some French ladies complaining about it and most probably for very good reason. Years ago osteoporosis was thought to be caused by wooden match sticks! We have come a long way but that doesn't necessarily mean biologic drugs are the best for ALL concerned. Be well~

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Re: Gloria (# 2647)

My last injection was January 2016. for 6 months I suffered a continual hot flash, rash and itching that did not go away. Memory problems that worsened, and it caused the autoimmune disorder (Hashimotos to worsen). I now suffer from the rash and itching from many things when applied to my skin anywhere on my body. With supplements my memory and swelling are improved. As Sal and Poodle say this will be with you in some degree for many yrs to life. Elaine

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Re: Faith (# 2658)

Has anyone noticed that in the new ads they now list some of the same side effects that they had been denying ?

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Re: Jennifer (# 2657)

If you did not have these issues before Prolia can for sure cause the issues you are having. Nothing to be done but stay away from what you know causes exacerbation of the hives ect. Whole food vitamins, antioxidants, polyphenols are important. Maintain a whole food diet and get your calcium via your foods not supplements. collagen in your coffee in am helps keep your calcium levels up. Bone broth is good as well.

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Re: Marion (# 2655)

There is one other option left for a blood thinner and MD's don't particularly like it. Lovenox - one has to do a small subcutaneous injection daily. I used it to prevent a blood clot and had zero problems with it. Used it for a good three months. Docs are pretty busy now and don't like to waste time messing with Warfarin. It's so much easier for them to use the new one. I have not tried this new one and I really don't want to. When I talked to my Orthopedic Surgeon in June 2018 we decided to stay with the Lovenox. Hugs~Pood

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Re: sal (# 2663)

I have just seen a UK cancer research site which lists Prolia, together with Xgeva, as causing most of the side-effects we have experienced. It seems that our reports of dreadful reactions are being recognised in some quarters. It is interesting to read that Prolia and Xgeva are being lumped together now, when previously I had read that, seemingly paradoxically, Prolia had more side-effects than the higher dosage Xgeva. I guess that NOT having cancer still does make a difference.

A year of lethargy after an injection is acknowledged, with advice about rest and lowered expectations about activity. No-one ever warned me about that or its effect on my ability to work. Personally disastrous.

It is fascinating to read once again that these phenomena, e.g. rashes, should be referred to a doctor. My GP seems to have acknowledged the reality of side-effects without grasping their implications, while my prescribing endocrinologist seemed sceptical. And as for taking a burning rash to an emergency department, well, I tried it once on a night of desperation and I might as well have been in Fantasyland. I left humiliated and still in agony.
It was what some medical sites recommended as a matter of urgency!

Tender, swollen skin and allergic reactions are supposedly 'rare' even now, but it seems that the weight of evidence is mounting.
We will be vindicated for reporting our supposedly imaginary side-effects, but the lack of transparency about adverse effects and the lack of options that we were offered, largely due to Amgen's suppression of information to prescribers, is thoroughly reprehensible.

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Re: JenjiOz (# 2664)

For 19 years my Hypothyroidism had been stable on the same dose if the same drug for18 years. Since starting Prolia in July 2016 landing in Jan.2017
My thyroid has been deregulated 4 times, the last time just recently !

There must be a relationship.

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Prolia has been a nightmare for me. I had my first shot in 2012, without being given any info about the horrible side effects! My body may never be the same. I am still suffering most of the horrible side effects of this drug. It is now being used for bone cancer patients! I took it for osteopenia. As I stated, this drug has been and still is a living nightmare for me. There should be a class action lawsuit against Amgen, the maker of this drug. And the FDA should open their eyes to the many negative post on Prolia, aka, denosumab, and Xgeva. Still suffering. Wish I could find help for the horrible side effects I am still having, and my last shot was in 2015!!

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Re: JenjiOz (# 2681)

I have had a lot of skin problems, even have become allergic to animals, dogs and cats. And I loved my animals. Had to give away my last cat. Traveled with her in the car, skin started breaking out. Really bad, then started breaking out at home from her. It was terrible. I have had most of the horrible side effects of Prolia. I wish I had known before I ever took the first injection. A horrible drug for me and it looks like a lot of others that have taken it. As I said, a horrible drug. FDA needs to step in and do something. Prolia has been a nightmare for me personally!!!

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Re: Verwon (# 1)

Prolia has been and still is a horrible nightmare for me personally. Yes, it is now being used to treat cancer patients, and I had a very close friend that was given this drug for a mild case of cancer, they never told her of the side effects it would have on her heart. Sorry to say, she did not survive. The drug or not, I cannot say for sure, nor can her family, but we are convinced that it hastened her death. It is poison, and should be taken off the market. Poison for me and many others!

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Re: sal (# 2692)

I am also having parathyroid problems. Now have to add an endocrinologist to the list of doctors I have to consult to get rid of problems I never had before Prolia. My life schedule has narrowed to multiple doctor appointments and lab tests in hopes of staying ahead of the health problems.

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Re: sal (# 2701)

Same here.... I have suffered as you wouldn't believe since I received that Prolia shot on March 30, 2017... I had severe autoimmune responses to this biological poison. Let's not forget that Prolia "plays" with the immune system in order to allow the recycling of otherwise "disposable" bone back onto our healthy bones.... (causing ridiculous fractures if we stop using Prolia, or if we use it for too long....).... In my case, I developed Graves disease.... and what is worse, I also developed TED (Thyroid Eye Disease)... I will have to receive radiotherapy around the eye orbits in order to stop the compression of the optical nerve....Which was causing severe visual loss.... I have suffered a year and 9 months for the one and only injection of this monoclonal antibody derived from the ovaries of some hamsters in China.... Was I ever told this. Never. Has my Dr. at least hinted at the possibility that I am right when I affirm that this happened 4 days after the one and only injection and I have been sick since.... No. He insists it is not Prolia.... I can't wait for a legal case on this horrible poison.

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Re: Maritere (# 2702)

I took 2 shots, then no more. The side effects were unbearable. In addition, my previously stabilized hypothyroidism has been unstable ever since. I also believe that Prolia negatively affected me autoimmune wise. This is a highly toxic drug.

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Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happ...

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I had my infusion Mar 4 2015. I have experienced severe stomach pains, leg pains that wake me up at night, a horrible dr...

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I developed a red burning itchy lumpy rash after one injection of Prolia. Mainly on face neck chest arms scalp. Anyone e...

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I'm a 59 year old female, diagnosed with Behcet's Disease and I use Prednisone for treatment for my weekly flare...

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I am 60 yrs old and suffer from osteoarthritis, osteoporosis, and myofascial pain syndrome. After discussing with my end...

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I am 81 and had my first Prolia Shot May 7, 2015 and after three weeks I have developed a red rash looking sight UNDER t...

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Aprox 2 weeks after the prolia injection I started to experience nausea and weight loss. Also, loss of appetite and a ke...

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I am not going to have my next shot of Prolia due 11 June. I have already had two injections and lately have suffered ho...

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I am a 57 year old female who has -2.5 bone density scores on hips and -3.4 in the spine. I used Forteo for 2 years, but...

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What does the pharmaceutical people of Prolia advised regarding its side effects? ## Hello, Lala! How are you? They do w...

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