Prolia Side Effects (Page 148) (Top voted first)

I would like to know of any side effects others may have experienced after receiving Prolia infusions. Up to now I have none.

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Re: Laura (# 2489)

I was taken off Xarelto by my reluctant hematologist and put onto Eliquis. However I find the side effects are pretty much identical. I'm due to have another consultation in June. I'm at my wits end about it all because any medico I speak to says it's neuralgia. The strange thing is, is that the burning sensation in all my limbs is only evident when I am trying to sleep. Does anyone else find this happens?

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Re: Tomas (# 2487)

Did some more research and found out that a 2017 meta-analysis of studies concluded that Prolia isn't even effective for men!!! Fosamax is, though. Am SURE no Amgen drug rep ever told my rheumatologist about this 2017 paper:

ncbi.nlm.nih.gov/pmc/articles/PMC5358515

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Re: Tomas (# 2487)

I had no rebound effects. As for taking another drug, see my earlier post regarding the European commission findings.. If you have no history of falls,
you might want to reconsider taking another drug.

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Re: Poodle (# 2475)

I can attest to side effects going on years after my last injection. It has been almost 2 years since my 3rd and last injection and I'm still dealing with muscle pain, dry mouth, mouth sensitivity and joint pain. Not to mention gum grafts, implants etc.due to tooth infections. Now I could blame this on aging but I had absolutely none of this prior to Prolia . Previously whenever I had any muscle pain it was attributed to something I had experienced.....overuse, digging in the garden, etc. So yes, the long term effects don't miraculously disappear after Prolia is stopped. I wish! The cost to my enjoyment of life is, at times, most depressing.
I just read an article online about my prescribing MD and how she worked along with drug companies doing trials on new drugs. Certainly I was never told I was in a trial but it does make me question why she was so eager to have me take Prolia! I certainly never signed anything. I'll never know!

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Re: Laura (# 2489)

Laura, my husband has atrial fib and was put on pradaxa. He had a stoke anyway and could not be given the clot buster because of possible bleeding. His cardiologist(a new one, I might add) put him on warfarin and he's been fine since. As he said, warfarin is tried and true. Yes you do have to have regular blood work done but at least we know that it's safe with no side effects except for bruising which the others also cause. Not too sure why you're on a blood thinner or why you weren't prescribed warfarin.

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Judy (# 2494) --

I don't believe they did one in Canada. First Amgen sent mice into space with Prolia. Interesting, but what does that have to do with humans. We are not lab rats. Secondly, the clinical trial was for 11 whole months in the US. From 11 whole months they came up with the side effects and their trial is available to view on line. I'm quite sure Canada approved it only because the US did. Often times Canada is first with a drug from an European country, but because Amgen is from California and is an American as apple pie and hot dogs, the US led the way for it to be in all countries. Now you know exactly where to place the blame -- the FDA in the USA. Be well~

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Marion (# 2499) --

See my post from May 21. The European findings base the risk of fracture on a history of falling on bone density numbers. So, unless one has a history of falling, why take these toxic drugs?

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Re: Marion (# 2501)

HI~There is a shot (injection) that is VERY EXPENSIVE but it will remove that clot from your leg in a couple of minutes. Insurance does pay for it. If you let them be, it become hardened in there and then one has to have radiologist surgeons go in and clean out the vein. If it gets too hard (as left in the win for a year), then the radiologist surgeons cannot do anything about it and you have a large vein that cannot be used again so in come the varicose veins and if you ever have to have a total knee replacement, the surgeon has to know the exact location of that old clot so he does not cut into it. In my opinion, it's best to use the expensive injection and end the mess. You will still be on blood thinners until they find out what is the cause.. Mine was from being on Pred. for a full year and my Dr. did not taper me off. Just cold turkey and my blood went nutzzzz with 2 DVT's and a matching pair of saddled PE's. I was on warfarin for a couple of years and as they often happen after a major joint replacement, I will be on it for a little while this summer. Family Dr. is suggesting Eloquis but one cannot have that with spinals so it will be warfarin. Last time I used Lovenox and it was very easy. A tiny little injection into folded skin on the tummy. Sometimes our Drs. are our worst enemies even though they think they are helping us. Even my Vet for my Poodle takes her off of Pred. very, very, slowly. I think the clot buster is called T-PA but not sure. Hope this helps you some. Hugs~

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Re: Poodle (# 2493)

Reply to myself for Marion. I think this person was in 2014 or 2015 in the back pages here on Medschat. I'm sure you can find the post if you look. Hugs~

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Re: Poodle (# 2503)

Thank you for all that. I would rather go on Warfarin too since Eliquis has the same effects for me as Xarelto had. However I have no knee or hip probs so no worries there. I know that Warfarin can be a pain because of the regular blood testing but I'll check with my hematologist when I see him soon. How do you cope with it?

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Re: Marion (# 2507)

Question please. Have you always had the Protein C deficiency or is it new with Prolia? The reason I am asking is because Prolia takes the worst of our DNA and uses it against us. We are having diseases we never knew we had in the past because Prolia brings it to the front and center. Most people with your blood clotting problem have had it since childhood. I just want to make sure I put the blame where it belongs. Yes, the neuralgia tinglings are not new here. Be well~

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Re: Poodle (# 2509)

Hi again. My Protein C Deficiency was diagnosed before the Prolia shots. My whole family including 3 of the 4 kids and six of the 9 grand-kids tested so far have either that or factor V Leiden or both so in no way can I blame the Prolia. However I have not ever suffered so many aches and pains since that first Prolia shot about 3 years ago. I was recently diagnosed with Hypothyroidism recently but that may have been present earlier but just not picked up.

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Re: Bubbles (# 2511)

How long will it be before you know if the oil is working?

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Re tooth loss and bone grafts as a result of Prolia, I was wondering how long after a bone graft others had to wait for the actual implant. I had a bone graft 4 months ago and saw the oral surgeon yesterday. She wants me back in another 3 months for X-rays etc to see if it's progressed to the point that she can do the implant. I have been reading online that usually it can take 4-6 months. It will be 7 months since the graft. My front tooth was pulled the beginning of July last year and I have been wearing a flipper since then. I hate it and am slowly losing patience . Has anyone else had to wait what I consider a longer than normal time? Maybe it's my age and things take longer than it would for someone in their 20s and 30s!

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Re: Linda (# 2515)

Thanks Linda. I've had an implant with a molar which didn't require a bone graft but apparently there quite often is a problem with lack of enough bone in the upper front teeth.I'm still hoping that after 7 months they'll be able to do the implant as wearing this "flipper" is most uncomfortable but I am too vain to be seen in public with no front tooth! where exactly did you have the bone graft....a front tooth?

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The side effects of Prolia are horrible, I know, had my last one in 2015 and am still suffering from it. It is a horrible drug, poison, should be taken off the market.

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Gloria (# 2519) --

And Amgen claims that side affects are ronly rare ! Of course they also claim that these are not side affects. A pretty big coincidence !

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Re: Poodle (# 2519)

Poodle,it was't necrosis I had.My immune system became compromised and I developed an infection in my tooth. Even though my dentist put me on antibiotics which helped but the tooth was so weakened and decay had eaten away to the point that the tooth became loose and eventually the only answer was to pull it. By the way I also had sores in my mouth that didn't respond to any drugs I was given....just more side effects from them. Still have the mouth problem and can no longer eat anything spicy , but that's another story that I am plagued with. I couldn't have the bone graft and implant done at the same time as there was too much bone loss. The oral surgeon had hoped she could but it wasn't feasible .so...I wait! I had been worried about my jaw as I have had 2 surgeries on it due to TMJ and had voiced my concerns to the MD who prescribed Prolia and she reassured me that any side effects were very rare! Guess she was wrong!!!
Yes all of this is very costly which insurance doesn't cover but I consider myself lucky that, at least, we can afford it. I have 2 excellent dentists here inToronto who I trust implicitly and who have shown great compassion for what I've dealt with having taken this drug, Prolia.

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Prolia is a nightmare. It changed my life and my ability to physically move, has almost disabled me. HORRIBLE DRUG, POISON, hope there is a class action law suit soon. FDA take it off the market/

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Re: Gloria (# 2524)

I would be shocked if that ever happened, there is a LOT of money to be made.

I have made myself an ambassador to spread the word about the horrible drug and its toxicity. I will tell anyone who will listen. Instead, I urge a more natural approach.

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Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happ...

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I am a 57 year old female who has -2.5 bone density scores on hips and -3.4 in the spine. I used Forteo for 2 years, but...

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What does the pharmaceutical people of Prolia advised regarding its side effects? ## Hello, Lala! How are you? They do w...

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