Prolia Side Effects Duration (Page 9) (Top voted first)

Would like to know if anyone had side effects from Prolia but they went away - and how long did it take for that to happen?

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Re: Katherine (# 9)

I. Had. My 4th. Prolia. Shot in. December. And I now have pain all over my body l have decided stop the prolia. Going to. Seek alternative and do accupuncture for the pain. Glad your mom is doing better

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Re: Alice Allen (# 140)

My regular doctor says my left shoulder problems stem from a rotator cuff issue. Waiting to hear if the x-rays reveal anything.

I just had two x-rays on my lower back for constant pain. My lower back hurt before but it has increasingly gotten worse. My first suspicion is the Prolia. Do you think I'm wrong? Has anyone else had these problems? I take Plaquenil for osteo and inflammatory arthritis and I have fibromyalgia.

Thanks y'all so much for the help.

Hugs,
Nikki

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Re: BB (# 18)

Yes. I only had two shots and was stopped because of breathing problems. It has been over two years since the last shot and I am still experiencing breathing problems.

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Re: Shirley (# 147)

Hi Shirley, I also have been experiencing all over body pain and joint pain after my 4th shot in December 2017. I think I am going to stop the prolia. I have been on the heating pad and tylenol. It does scare me to go off of it but scared to stay on it.

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Re: Barb (# 145)

Barb,
High cholesterol is one of the side effects of Prolia. I now have it when it was never an issue before. I'm praying since I'm off Prolia it will resolve on its own. Sending you hugs and prayers for a full recovery.

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Re: Nikki (# 149)

I am sorry you and so many others are going through this ordeal. I also had x-rays of knees and CT of my back resulting in useless physical therapy. I will encourage you to follow through with ANYTHING you think might help. I started having these symptoms with Zometa and that is why the Dr changed me to the Prolia. I too, had ER+ breast cancer and was prescribed Arimidex, another drug that blocks estrogen. The lack of estrogen, especially in women, increases the risks of osteoporosis. So we are being treated with one drug to "fix" what another drug is causing. Until I started piecing things together and doing research, I was and still am wondering what I have gotten myself into. After starting the Arimidex my cholesterol went up. Once changing over to Prolia....my cholesterol is now OVER 300! I was being prescribed antibiotics (Levaquin, which is trouble in itself) every 6-8 weeks after finishing a round. One ENT told me the arimidex could lower my immunity, Oncologist said he must have been thinking I was talking about chemotherapy and that Arimidex would NOT lower immunity. Hmmmm....do doctors ever read the package inserts to the drugs they prescribe??? On my own, (without Dr's consent) I stopped the Arimidex. I was not aware of the pain I had been in just because of that drug. So he prescribed a different drug to take the place of the Arimidex.

Then after I checked with the pharmacy and found out the medicine was going to cost over $110 for a one month supply, I said, "Uh-uh!!" Around about that time I thought....... if I don't take something to lower my estrogen then I will not be "required" to take anything to "build up" my bones. I am in NO way suggesting that you stop any of your medicines or go against your doctor's orders. I am just, without making yourself paranoid, pay close attention to what your body is telling you. You have only this one body on this earth. I was given my body to take care of and I am the only one who lives in it. I see the oncologist again in March. I don't know what I may be up against when I say I don't want anything else. My breast CA was Class 1. I know that this Cancer is more apt to come back in bone than anywhere else, but taking these medicines does not absolutely prevent it either. Two years after I had bilateral mastectomy I had a total thyroidectomy for Thyroid CA. I truly wish each of you improvement of any physical and/or emotional pain This drug has caused. One more thing, from what I have read, and please someone correct me if I am wrong, but out of ALL the thousands of people who were in the trial studies... NONE "0" complained of the severe bone, joint and muscle pain. FDA got these complaints AFTER the drug got put on the market.....WHAT?

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Re: Shirley (# 153)

Did you know also, they specifically excluded people with compromised immune systems from the test? So how in the heck can they feel comfortable giving that to anyone who has had Chemo, or HIV, or old age? This is a death drug.

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Re: Rosemarie (# 144)
No, No, No. Prolia does not stay in your system forever. A tiny molecule will be left but it's not enough to hurt you any more than that aspirin you had 20 years ago. They are both made from products from our Earth. Prolia clears out of the human body in 6 months. The half life is 16 days so that means in 16 days 1/2 of the Prolia injection leaves then in another 16 days 1/2 of that remaining half until we reach the end of the 5th month. That does not mean that the side effects leave with it. Some side effects do and others linger for years as our bodies try to repair the damage done to it. This is the first year I have been able to have any gluten since my injection years ago. I guess it just finally got over it but it sure took an awful long time. The muscle/tendon in my neck is no longer sore either. It finally left too. I did get the back fractures from stopping it. Everything in there is a total mess now that I don't pay that much attention to it. Be well~Pood

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Re: Maritere (# 139)
I am sorry that you are a fellow breast cancer survivor but the good news is we did survive. Prolia is not used as chemotherapy under it's other name. It is to build up bone quickly in people that the chemo has ruined their bones so they will not suffer a spinal collapse or another very nasty side bone side effect from chemo. They get more of the active ingredient than we do is the only difference between Prolia and Xgeva. Both are to build up bones. There are specific eye drops that contain Prednisone. I'm not sure I have it spelled correctly "Prednisonioli". I had to take it when I had surgery on my macula. I had that one as an anti-inflammatory, one for dilating and an anti-bacterial. Mine was from a retinal surgeon but any can Rx drugs in the US. I distinctly remember having to go off of the Pred. drops slowly after he was sure I had no more inflammation. It does exist and you should be able to have it. Prednisone can be a very safe drug if it is stopped correctly which means slowly tapering off. I know all about the skin, hair and nails. No longer healthy and nice. Be well~Pood

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Re: Nikki (# 149)

Hey Nikki, I already had an appointment scheduled with my GP, just for a follow up. Thought I'd get her opinion about the Prolia. Just like many others, she doesn't think my symptoms are caused from the side effects of Prolia. She order lab work and gave an RX of Prednisone. She told me that if the Predisone helps then it would highly suggest Poymyalgia Rheumatica. That also had crossed my mind in trying to figure out what was going wrong with my body, but it is so much easier to blame a medication that you can stop to get the pain to end. So, I MAY have jumped the gun in my earlier, angrier post. I am in limbo now with more specialists to see. I am SO tired and frustrated.

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Re: Shirley (# 160)

I think you should go with your first gut reaction that it may be the prolia. several years ago they started me on fosamax and I hurt from head to toe and was out of breath. doctor didn't believe me so I went off a month and went back on. same thing happened . with the prolia injection a little harder to do this. I am on prolia two years and after my last shot in december I hurt all over. not sure if am going to continue

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Re: Vickie (# 161)

Did you also have ER+ breast CA also, I didn't go back and read all the comments, and I've read SO much to find answers I cant remember? I do worry about the CA coming back in the bones, as there is a fairly high recurrence to the bone, but I don't know how to cope with THIS pain, I am no stranger to pain...Fibromyalgia, Chronic Back Pain, Osteoarthritis among other diagnoses! Has anyone else been given prednisone(steroids) after telling your doctor about the pain you are having??? I don't know exactly what makes the body react to Prolia in this way, ( except maybe how the medication is metabolized by the CYP3A4 enzyme of the liver) but if it is an inflammatory process the Prednisone should help. Do you know if the reaction IS inflammatory?

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Re: Shirley (# 163)

Have your Osteo Doc. check for Osteomyelitis. I know Prolio lowers your immune system, and this could set in on your joints.

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I was given my 3rd Prolia injection in December. I take it to prevent bone loss after being prescribed Arimidex due to ER+. Two days later I visited GP with bladder pain during urination. Was given Sulfa for a possible infection. My U/A and culture were both negative. Then I started having debilitation joint and muscle pain. If I straightened out my legs while lying down, my knees would SCREAM. My neck arms and shoulders became SO painful, stiff and sore. My arms feel like lead! Saw my GP for just a monthly checkup yesterday and told her my symptoms. She did not think the Prolia was the cause of the pain. She ordered Rheumatic/Autoimmune Disease labs. She gave me Prednisone. She said if Prednisone helps she would not be quick to blame the Prolia and her diagnosis would be Polymyalgia Rheumatica. After starting the Prednisone yesterday 20mg I did not hobble when I got out of bed this AM and my shoulders and arms are somewhat better (pain is not as intense). I am also treated for Chronic Back Pain (Norco 5mgs once a day), Osteoarthritis (Ultram 50mgs twice a day). Neither of which really helps my current pain from Fibromyalgia - I no longer take Lyrica for that because when I added the Ultram, I stayed too sleepy. But the fibo pain has been much better since I quit work. I am unable to take NSAIDs, due to elevated kidney enzymes while taking Mobic. I was wondering if anyone else has been given Prednisone for the pain OR been on Prednisone for another reason and noticed an improvement in the joint and muscle pain? I appreciate any comments Thank you.

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may a dialysis patient of 75 year use prolia injection if that person does not urinate.

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Re: teddt (# 179)

Do you have an address for them. I have been sick for over to years now with shortness of breath.

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I want to know if some dialyse patiënt died after taking ProliA

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Has anyone else developed a macular hole in the eye after Prolia?

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Re: Janet (# 192)

Yes I have but I don't think it is related to Prolia at all. I had what is called a macular pucker because as we get older the fluid in your eyes starts to leave. Mine got stuck and was pulling on my macula which is the center of the retina. I have the same thing happening in the other eye but it is not affecting my vision because its pulling from the side. It will require surgery about the middle of this coming August. I believe mine to be from age and at one time quite myopic. My surgeon who is one of the most respected in the western US has never thought it to be from a drug. I don't think I am much help to you in this regard. be well~

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Re: Janet (# 192)

Janet - I think they can use an endo laser to close that hole up. That's what mine uses on all retina tears regardless of position. Be well~

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