Eliquis And Weight: I Need The Truth (Top voted first)

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Today I am speaking with my hemotologist about switching from Xarelto to Eliquis. Xarelto has caused me, a runner with a very slim diet, to gain almost 14 pounds in 4 weeks. 7 of those pounds in the last two weeks.

I need to know of any serious weight gain issues with Eliquis. Doctors always swear that the side effects listed are the only ones but I was never told by my doctor nor the literature that Xarelto causes abnormal weight gain either. Google had to tell me that after yesterday's terrible weigh-in. I'm looking for absolute candor. I am 34 and female and I'd be taking it for PE.

Thanks.

102 Replies (6 Pages)

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1

Anytime you want to know all possible side effects, it's best to ask a pharmacist, visit a site like this, or research it on your own. Doctor's aren't trained as much in medications, so unfortunately, they usually only know the very basic most common ones for any given medication.

Now, as to the Eliquis, it usually causes decreased appetite, in most people that take it, so weight gain isn't listed.

Its typical side effects may possibly include nausea, headache, increased risk of bleeding, anemia and hypotension.

Is there anything else I can help with?

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10

Hi. I am working out 90 minutes a day 5 days a week. I have always watched my diet and concentrated on the right foods for triathlon etc. I am always between 179-183. 183 I would consider the point when I put on the brakes and refocus on diet. Usually the end of summer coming off 2 months of beach and bbq. Now since on Eliquis, I have shot up 10 pounds. I have reduced my calories, continued working out. I rarely drop below 190. It is frustrating. Dr said it slows the metabolism.

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6

I'm on 5mg eliquis and I'm not able to eat much at all I've lost about 35 poumds. Is there anything I can take to keep weight on???

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12

I'm having similar problems to Bruce. I started with Eliquis in November because of a blood clot in a lung (which caused an inflammation). I stayed off the training for 2 months to let the inflammation heal (until the middle of January). During this time nothing happened to my weight, which is to be expected, since I probably ate a bit less than when I hit the gym 5 times a week. I stayed at a solid 97Kg (213-214lbs).

I usually have no problem maintaining my weight at a diet of 3000-3500 Calories. This did not change with Eliquis.
However, at the end of January i started my yearly cut (I've done quite a few of these before). I dropped to 2800 Calories for a week, the weight didn't budge. My thought was; "Strange... Oh well, guess I'll drop it down a bit". I dropped to 2600 Calories for a week, the weight didn't budge. I started to get suspicious, but thought I might just have retained water. I dropped to 2400 Calories for a week, the weight didn't budge. I now realized something is not as it should. Eliquis? I dropped to 2200 Calories for a week, the weight didn't budge. I see some more contours and stuff in the mirror, but the weight is the same. I am now on my second week of 2200 Calories and still weigh the same. Normally I might be at 2400-2500 after 4 weeks. This result feels so improbable and unlike how my body has reacted to cutting before.

With the above adjustments I should have lost up to around 3Kg (6.5lbs). I don't feel bloated, fatigue, loss of appetite or anything like that. There has been no weight gain for me. But the weight loss seems impossible. I'm 30 years old and feel that this is weird. Is there any way for Eliquis to make me retain as much weight in water as I lose in fat? I have a doctors appointment in May again. Maybe I'll get some clarification then.

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9

I'm on Eliquis 5 mgs twice a day. In the last few days I have switched myself to 2.5 mgs twice a day. I'm extremely fatigued. I was on Eliquis for 3 months because of a provoked dvt in my leg last July and then I came off of it in October per my PCP. I have no energy; my PCP doesn't believe me. I know it is the Eliquis. What else can I take? I'm having to drag myself through the day. Even if I sleep 12 or 13 hours I'm still tired and would continue sleeping if my husband doesn't make me get up. Feeling discouraged and depressed.

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15

Joe, I've being having the same problem for a few years now. I cannot lose weight and I watch my diet and workout 5 times a week. Ive been taking this medication for about 2 years and have gradually add weight for no reason...but cant take it off...no matter what I do.

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11

I have been on Eliquis 7 weeks and have gained 7 pounds!!!!
I see your post is old but if you see this I am wondering about your experience if you switched to it...

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20

I cannot lose 1 pound since I started on Eliquis. I am very tired most of the day. I took a water pill for 2 days and still no weight loss.

Was this helpful? 7
17

Hi:
I have been on Eliqus 7 months now after having a Pe and I've gained at least 2 to 3 lbs per month while on Eliqus, my doctor says it's because I'm not as active as I was prior to the Pe, I think it's because of the Eliqus...

Concerned and overweight

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7

My husband has begun taking Eliquis he has lost 16 lbs in 3 months and also urinates a lot he has an appointment with his doctor in a week. He does not like the overall way he feels.

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18

Hi:
My name is Rhonda and I had a PE In August and was put on Eliqus and have been gaining weight and cannot get it off even counting calories, waking and watching my diet, I too think it's the Eliqus and once gaining it's hard to not gain while on Eliqus.

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19

I have develops right back pain and a sharp stabbing pain around you front. Have a liver ultra sound and gallbladder all was well. Could eliguos cause this.

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23

Have gained weight since starting Eliquis 3 weeks ago. I find it increased my appetite and also I am retaining a lot of water, feeling bloated most of the time. Unfortunately, it gives me heartburn and upset stomach, which is why I think it's important that I eat when I take the medicine. Also, I am experiencing severe fatigue, resulting in my being less active and less likely to burn off the extra calories from the food. This is just what I'm experiencing, don't know if anyone else has same side effects. Hope this helps.

Was this helpful? 5
24

I'very been taking Eliquis for 2 months and have gained 25 lbs. Eating habits or amount of exercise not changed. I also feel tired all the time.

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3

That's all I wanted to know. As an update, I took OTC diuretics and in 3 days I was back at my normal weight but since I don't want to have to do that for the course of this treatment and since Xarelto has also caused serious palpitations and chest pains, I'm still going to switch to Eliquis.

Thanks.

Was this helpful? 5
5

Xarelto made me very very sick and I switched to Eliquis with no side effects and in fact I lost weight being on it unless it was the fact that I felt so much better and was more active..Either way I feel much better

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16

Update. I do not have a DVT in my left leg. The swelling and soreness is actually due to exercise. I'm continuing to lose weight, which is my goal.

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33

Re: gt (# 7) Expand Referenced Message

My husband was on eliquis for 7 months and lost over 40lbs had headaches , low iron and other problems amd just not feeling well and in july 2017 had a large brain bleed and he passed away. I don't know if anyone knows this but if you have a bleed while taking this drug there is no antidote to stop the bleeding .I believe this medication killed him because he was never a sick person and only 55 and so full of life, he also was telling his Dr this whole time about his symptoms and not one of them ever thought of thr medication. His iron levels were also low.

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68

Re: LoriE (# 11) Expand Referenced Message

Hi, I’m on Eliquis 5 mg twice a day for about 6 months now, to treat atrial fibrillation. I’m going to see my doctor next week, as I’ve gained approximately 15 pounds with no change in diet, & even a slight increase in daily activity.
Fatigue has been a factor too & seems to be increasing along with the added weight. I’m pretty discouraged. I also get a “cold water” sensation in my legs & have had swelling in my legs. Anyone else experienced this?

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14

I've been on Eliquis for about 8 weeks and have lost 12 lbs in that period of time, even wit a cruise thrown in. I've been trying to lose, so I don't think it has has an adverse effect on my efforts. I had some indigestion the 1st week and then no other side effects. I have more energy, which could be attributed to many things including weight loss, PE has cleared up, exercise and started using a CPAP for sleep apnea.
My only problem is I think I have developed another DVT in my leg. Will know more tomorrow. I take 5mg twice daily.

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