Efudex 5% And Silkis 3
(Newest replies first)

My new dermatologist has prescribed a one-week per month treatment over four months, applying Silkis 3 in the morning and Efudex 5% at bedtime. I have used Efudex before in one spot, with the expected itching and scabs. What happens when I apply these creams all over my face and scalp, which don't have many particular keratosis spots? My job involves working with the public.

REPLY

REPORT

For anyone coming to this late ... I had started the 4 week trip to hell with straight Efudex/Efudix* but came across info about the combo treatment on day 3, so I raced out and bought some Dovonex/Daivonex* to mix in and proceeded from there, hopefully with only a few more days to go on this route rather than 2-3 weeks (or more).

I tried to find out if Silkis - active ingredient Calcitriol - could be substituted for Dovonex - active ingredient Calcipotriol - but couldn't. So I stuck with the Dovonex because Calcipotriol was used in the Harvard trial, not Calcitriol. The only reason to want to use the Calcitriol is that Silkis is cheaper than Dovonex. But considering the objective here, I'd advise against trying to save a couple of bucks; just use the recommended components and stay on the safe side (IMHO).

I'm on day 2 of using the combo now and haven't seen much effect on my face, neck or left forearm, though I expect the arm to take a fair bit longer going by everything I've read (and I've read a lot over the last few days!)

* The names of these drugs vary by region; I'm in Mexico and the latter names are used here, and in quite a few other countries, while the former are used in the US.

REPLY

Was this helpful? 0

Re: Gini (# 1)

How did this protocol work for you? Do you react quickly. How soon did the redness go away? I’m using a Efudex and a synthetic D3 derivative gel called Calcipotriol. I mix them 50-50 over five day. I am on day one of healing and every square inch of my face is extremely red and beginning to lightly peel. I am to do follow this protocol once a month for three months. Thanks

REPLY

Was this helpful? 0

My dermatologist prescribed Efudex and Desonide last week! Beginning tonight... 7 days Efudex and Desonide am and Desonide pm, followed by Desonide twice a day for 3 days, then stop for 3 weeks. Repeat 4 times after that !

REPLY

Was this helpful? 0

I have quit treating my face and neck with Efudex and I am still peeling and having breakouts and the usual recovery. I ...

1 REPLY

Hi, I have been using the combined cream for 4 days twice a day and totally feel nauseous and a little dizzy. Did anyone...

1 REPLY

My husband has been prescribed Efudex for 10 days (morning and evening on his scalp). Also, Dovonex twice daily and pop-...

I have been using Efudex on my fore arms and the back of my hands for two weeks. Three weeks will be the total time of a...

I am applying efudex to my face. I usually shave every 2 days. Should I shave everyday so that my facial hairs do not in...

1 REPLY

Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this c...

28 REPLIES

Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50...

16 REPLIES

Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swe...

14 REPLIES

Has anyone used Efudex on their head? I'm interested in any side effects on hair deterioration or loss. ## Hello Hoo...

7 REPLIES

How and when should I apply Efudex to my face? ## This is a drug used to treat certain types of cancer. How often and ho...

5 REPLIES