Effects Of Long Term Amitriptyline Use On The Heart (Page 2)
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After 20 years of taking amitriptyline for headaches I would like to find people who have had any heart related side effects after long term amitriptyline use.

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87

I was given this extra from my ENT Dr for coughing! It worked GREAT at 1 (10mg) tab at bedtime for about 1week. A couple months later - the cough is back and 3 (10mg) tabs are doing "Nothing" I've never been depressed but, this makes me kinda grumpy - don't like it!

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86

Hi Anne Marie
So sorry about your sister.
I , too was taking 200 mg of Elavil for migraine prevention for a year , and decided to change to something else (Topamax) At any rate while transitioning from Elavil to Topamax, I ended up in emergency 4 times within a span of 2 months with tachicardia which one doctor and one pharmisist said was attributed to Elavi. My cardiologist , on the other hand , strongly questioned this. Mysteriously there wasn't another tach attack after stopping Elavil cold turkey.

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85

Hi there,
i was taking Elavil (amin..) for headache prevention (200 mg) for about a year and along with 100 mg of Topamax for a short period when I was weaning offf Elavil

This resulted in 4 visits to emergency with tachicardia where my heartrate was well over 20 beats per minutes

Stopped Elavil and tachicardia also stopped even though cardiologist said it wasn't ecessarily due to the Elavil . Ha , ha !!

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84

I have been on elavl for 4 years for IBS. It helps but so many side affects . I makes me groggy , crave sweet and my dry mouth has caused bleeding gums ! I get off it and always had to get back on bc IBS returns and stomach pains . I am on 100 mg and cut that into 4 tabs . I also take Xanax. Has anyone else experienced this??

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83

My sister died 4 months ago at the age of 57. We just got the autopsy report and it says she died of "amitriptyline toxicity." She had told me she was taking 200 mg per day as migraine prevention. Her husband thinks she was taking it for more than a decade. she was also insulin-dependent diabetic. She was very cautious, so I'm pretty sure she didn't accidentally overdose and 'toxicity' sounds more like a buildup in her system. I'm hoping to get an written autopsy report so I can understand this better. She was also a very small person. She probably weighed about 105 pounds.

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82

It has ruined my life. I want off. I tried once. It's been yrs. The withdrawals are unbelievable. idk what to do. I was put on paxil too, along with a list of medications. Years wasted, I only exist. Till a couple yrs ago I didn't realize there was a world out there. I'm so sedated. I use to have dreams but thanks to drugs I've never been so scared in my life. Anyone thinking of using antidepressants don't, there is always another way. Drugs are exactly that, drugs. Most drugs make your problems into bigger problems!

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81

I have taken ambien and trazodone for 15 yrs. I have went to a half of ambien 5mg and a 100 mg of trazodone. It's an older drug not addicting. I know when
i miss a nite , I cannot sleep. I have heard coming off trazodone is a long procedure tho cause your body gets tolerant to it. I also used pantroprazone for 15 yrs til it starts not working and makes ur stomach worse. I guess that's what they are saying about all the stomach pills. I recently started some old ones back up after I been on them that long.. don't know if they help yet.

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80

I have been on a low dose for 22 years and haven't had any issues. I was starting to think being in this for this long wasn't good. I take it for FMS

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79

I was taking 200 mg of elavil for less than a year as a migraine preventative and I am convinced it brought on super ventricular tacichardia I had 3 spells within a 2 month period where I ended up in emergency and needed medicine given through IV to bring down the heart rate, because this had never happened before in my life and research suggests it can be a side effect. I believe in my case that it was.

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78

I have had close to 26 years of Amitrip at dosages of 150, maybe more. I gained 150 pounds. It does make one sleep. I have restarted Amitrip with Fluoxetine and I take 80 mgs of Fluoxetine and I'm sleeping better but feel awful. No get up and go. Oh, i restarted Plavix for stroke. Really hate plavix; Can't sleepl at all without amitrip and Fluoxetine

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77

Yes, this is a dangerous medication.... Many heart problems and decrease urine..I couldn't drink too much water or I.V. fluids..I felt like I would explode....it hurt my heart and breathing... Much shortness of breath ...this drug did so much more harm than any good. It should be banned

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76

I was on Elavil for 7 years when I didn't want to be on it anymore I weaned myself off of it very slowly I went to half a pill then a quarter of a pill then an eighth of the pill then I literally crushed it into small tiny pieces even to a powder...believe it or not i still felt the effects of the pill even in the tinyest doses and i did this over the course of several months.. you have to take your time to get your body used to less dosage depending on how many mgs you are taking.. it will work you just have to be patient I have fibromyalgia if it worked for me it's got to work for anybody because nothing works for me.. Just cut down as slow as you need to for your body to feel ok..once I stopped I felt better... good luck!

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75

I have been on this med for years and have suffered all your symptoms including enamel degradation. I'm on 40mg a day for severe neck and back pain. My pulses races and have now started with high blood pressure as well. I'm so worried about being on it but also scared of what the pain would be like without it. Does anyone know of other good meds to stop muscle spasms? I'd appreciate your help xxx

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74

Hi, I was wondering if any long time users of Endep have Idiopathic Pulmonary fibrosis? I have been diagnosed with this dreaded disease and I have Never Smoked. The only thing I can think of is that I have been taking Endep for approx. 20 years.

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73

I seems obvious that long term use, over 5 years at doses over 75mg, is not advisable. On the flip side, it appears that short term use , under 75mg seems to produce favorable results.

Does this sound correct?

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72

Could not agree w Mary more. I started taking masses doses of,Amitriptylline after my 22 yr old brother's death in a car accident, also for severe insomnia. GET OFF. It nearly destroyed my life.

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71

Hey Alex,

How are you doing now? I hope all is well. Your story touched me and I just wanted to reach out to you.

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70

Do whatever you can to get off Amitriptylline.
I was on large doses for 30 years for severe insomnia, and combined w other sleep meds, it was destroying my life. There is too much to my case to write here but GET OFF.

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69

Yes, I know about large doses of Amitriptylline over a long period of time. I started taking it 30 years ago after the death of my 22 yo brother unexpectedly-- by large size I mean 350 ng over the bulk of 6 years. I continued taking it after that time until recently. I took I in one single dose along w 50 mg Trazadone and 1-1/5 mg xanax. I was also taking Buspar for anxiety in the daytime and 200 ng of Zoloft for 7 yrs of mentally abusive treatment. I have stopped all of them except Zoloft which I want to be off of in 6 mos. In place for sleep I am taking only Restoril and I believe this will work. After getting off all of them, I experienced 7 nights of total lack of sleep. I was like a zombie-- then srmtarted Restoril. I have stopped alcohol and sugar and have become like a guard dog as to what I will let into my brain. What I have realized that for 30 yrs I was functioning while asleep. GET off all large doses of brain meds.

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68

Yes I'm currently experiencing a heart rate at sleep of 132 per minutes, massive head paid and major swelling in my knee and ankles. I'm reducing currently but that not an over night process.

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