Difference Between Adderall And Amphetamine Salts (Page 27)

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I was recently diagnosed with Adult ADD and have been prescribed Amphetamine Salts (Generic for Adderall) for a few months now. The initial dosage was one 10mg tablet/ three times a day and recently my Doctor upped the dosage to one 30mg tablet/ twice a day. I know that overall this has been very beneficial for me but I cant help but wonder if the generic brand (IR Amphetamine Salts) has less of the active ingredient, and more unnecessary side effects(irritability, fatigue). I know that while the active ingredients are likely to be the same, the "fillers" usually are not and even the active ingredients can vary up to 10%. I also know that everybody reacts differently depending on their bodies' make-up as well as the drugs and I have always reacted sensitively to any kind of drug. The more I "google" the more I want to stay away from the generic form. Also- almost every pharmacy around has little to no Adderall Brand IR tablets in stock, they only have the generic brands and possibly Adderall brand but only the Extended-Release. My Doctor seems to firmly believe that there is no difference between Adderall XR and Adderall IR, and because she prescribed me the generic form (Amphetamine Salts), she probably doesn't see a difference there either. I don't have the time to ask 10 doctors what they think so if anyone has any information or experiences please share! Thank you!

686 Replies (35 Pages)

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521

I know this post was done in 2013, but I hope you are able to read this. You need to change doctors. If you are feeling symptoms behind a medication and your doctor does not provide you with what will help you, then he is not the doctor to see. I have had ADD symtoms most of my life and I never knew what it was. I was always lost and confused and had extreme anxiety all my life. For years I struggled trying to find out why I couldn't focus and was all over the place. ADD and ADHD is a severe disease that controls your life. I have recently started to take the generic form of Adderall and it gave me an unbelievable migraine for a week. I stopped them and told my doctor. Yesterday, he then gave the generic Adderall and (Bystolic for my anxiety - 5 mgs.). My doctor told me to try the two medications because it would help me on both counts. I pray that my life gets better on these meds. I hope the same for you. Please change your doctor to someone who listens and does trial and error to help you.

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522

you r so right on hun'' i my self switch insurace and pharmacays'' all they had thier was amphetamine salts, my goodness they make me sleepy, hungry all the time, most of all i have to have my friends drive me places when im to sleepy r tired' and my hair is falling out'' my children ask '' mom why u sleep all the time?? so i went back to my doc' told him what was going on with me' we did some reserch and found a pharmacy that has what i been taken a long time now'''' so she is stupid""" just cant stop taking ur meds just like that'' i know my body i have a low tolerances when it comes to taking meds' who wants to be on theses things unless u need them'' and i know i do'' so put a sock in it''' dont judge without judging ur self first''' seawife'''

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523

you r so right on hun'' i my self switch insurace and pharmacays'' all they had thier was amphetamine salts, my goodness they make me sleepy, hungry all the time, most of all i have to have my friends drive me places when im to sleepy r tired' and my hair is falling out'' my children ask '' mom why u sleep all the time?? so i went back to my doc' told him what was going on with me' we did some reserch and found a pharmacy that has what i been taken a long time now'''' so she is stupid""" just cant stop taking ur meds just like that'' i know my body i have a low tolerances when it comes to taking meds' who wants to be on theses things unless u need them'' and i know i do'' so put a sock in it''' dont judge without judging ur self first''' Margert"

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524

You obviously have some addiction issues. How dare you speak to people you do not know about what they should or shouldn't do.
I have NEVER posted a response before today on any site. I have MS and need to continue to work. I have a job that is very detailed and also physically demanding at times. I often drive a couple hundred miles in a day.
Adderal is a lifesaver for me and for all the people on the road with me. My fatigue is severe and I will not go on disability unless I cannot possibly go on. I want my children to believe they can push through in life, work hard and not need anyone else to support them. Your insinuation that anyone takes Adderal is a drug addict is offensive, inaccurate and insulting.

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525

Great place to learn and listen to folks who have experienced the good and bad of Generic Adderall
I have been on Adderall 20mg 3 times a day.
I have been worried about generic for some time now.
Barr web site says not more than approx 6 months ago a recall on the medication. According to manufacturer they were adding 2x the active ingredient. R U Kidding? Now this month, prescription is horrible, no active ingredients, side effects so bad migraine for $120 So I am changing something very soon I am sick Thanks you guys

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526

My issue with this, besides the condescending tone and insulting presumptions and generalizations, lies in the inaccuracy of the information. Adderall IS an addictive substance, and it IS a stimulant, so in those regards it can be considered to belong to the same category as coke and methamphetamine, but it would also be the same category as caffeine. Not that going nuts with any of those substances is good for you or recommended, but the point is just because a stimulant medication is potentially addictive does not delegitimize its value; it should be worth assuming within reason that an adult can manage their own medication in their best self interest. And, addiction and recreational value aside, there are many, many medications that have no recreational value that can cause truly awful side effects, and many that cause chemical dependence on them anyway.
The most egregious error here, I think, is the assertion that amphetamine salts and methamphetamine are "in the same league". Their side effects present the same (increased heart rate, body temp and energy, appetite suppression, etc.), and that's about it. The chemical structure of methamphetamine, the full name of which is methylmethamphetamine, allows it to cross the blood-brain barrier more quickly and efficiently by action of the extra methyl group attached to the methamphetamine molecule. This is also what makes methamphetamine neurotoxic, and what "kills the joy" in people; really, this is an over-flooding of dopamine, which over a long period of time reduces the production of dopamine that occurs naturally in the brain. Adderall, while it can have a nasty withdrawal period if a larger dose is cut cold turkey, does not have the neurotoxic effect that methamphetamine does. The same goes for coke, not to mention the ROA for those substances significantly increases the risk of damage, whereas Adderall is ingested and absorbed with minimal damage, if any, depending on the individual.

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527

Wow, margarita, it sounds like you've had a bad experience with heavy drugs and are really condescending with the word "kido". Perhaps you're unable to use this drug but I've been using it for 5 yrs as needed and typically have to fill my script every other month. Yes I had to learn that it's a super drug and to be careful but in the end it's actually helped me significantly. There is one generic version over another that works well and for me that one is manufactured by tevo. I have my psych prescribe that one specifically. Good luck.

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528

I am sorry to see that this post was demoted, whatever that means. My son was prescribed Adderall, it triggered bipolar disorder. He had a great job (paid just shy of six figures), had an MBA, but the side effects of Adderall got the best of him. He lost his job, has been unable to find or retain even a low paying job, had to go to rehab (that kept him off Adderall for a year but he finally went back, although much less dose) and his paranoias came back even worse. He had to move back home at age of 34, is seeing psychologist, and waiting to get into psychiatrist to be placed on mood stabilizer in hopes of fending off the bipolar disorder. I CAUTION ANYONE AND EVEYRONE WHO TRIES ADDERALL OR ANY DERIVATIVE OF IT. This has cost me thousands of dollars, has robbed me of what should have been the best years of my life, has robbed my son of the most important years of his life, and he may never recover from it. It has also caused him to alienate all of his friends and family, including me. What was once a very popular and successful young man has turned into a depressed or manic (depending upon bipolar activity) shell of a man.

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529

I want to start by saying that I'm sympathetic to these feelings; bipolarism is scary, especially because it seems to hit out of nowhere; in fact, it usually presents itself sometime in the person's late teens - mid twenties, and often it gets misattributed to lifestyle or a moody "phase". I know this because I am bipolar. I was diagnosed in 2011, and I can attest that the last 1.5-2 years that I've been on Adderall, I have not seen a progression nor a significant change in my psychological state(s) that could fairly be attributed to the medication. I also want to emphasize that I'm not blaming anyone that has struggled with bipolarism and felt that their medications were exacerbating their problems and changing their lives. It's a fact that some people's change in psychological states to bipolar or schizophrenic etc. is chemically induced. But typically, there has to be a genetic disposition to bipolarism, some level of risk already posed. And even then, I acknowledge that some people take things too far with drugs and maybe some of them are the way they are because of X, Y, or Z drug. But ultimately, everything poses some risk, everything has the potential for addiction. The rate of alcoholism is many times that of other substance abuse, including coke, methamphetamine and opioids. But that doesn't mean it should be illegal. More to the point, many people suffer health issues from their medications, but it would be unfair and unnecessary, not to mention unconstitutional, to pull those medications from the market when they legitimately help people just because somebody had a bad experience or a negative reaction or even an overdose. People are going to do what they're going to do, and as long as they aren't causing damage/trauma/violence to the public or others, how can you justify taking the right to choose what goes in their bodies or what lifestyle they lead for "security"?

There's an excellent quote, one of my favorites, from Benjamin Franklin that states, "Any society that is willing to give up freedom for security deserves neither, and will lose both". It's a little dramatic to use it in this case, but where do you draw the line? It shouldn't be up to government to control what American adults consume or don't consume.

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530

No you do not feel effects from inactive ingredients.....they are INACTIVE. I also don't understand how you managed to identify the source of effects as the inactive ingredients and not the active ones. Whatever you felt was clearly due to the active ingredients only. This really shouldn't even require explanation.

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531

Estes 'anfetamínicos' realmente fazem grandes estragos, quando tomados de forma abusiva. A cabeça fica como um 'queijo suíço', 3 dias e 3 noites sem dormir e se alimentar, e com disposição para 'dar e vender'. Tudo é uma questão de paciência, até encontrar o remédio certo, seja uma combinação 'antidepressivo- ansiolítico', (estabilizantes de humor), pra mim é lenda. Tudo fica monótono e sem a menor graça. É 'efeito placebo'.Nas primeiras vezes, os anfetamínicos,se parecem com uma 'injeção de Felicidade, mesmo 1 comprimido apenas. Daí,o 'uso repetido' e quase contínuo, é difícil evitar. Realmente parecem 'abrir a cabeça', para um bem-estar.Com o tempo voltamos ao velho e bom 'arroz com feijão', e1 copo de suco, ou água, 1 café e um cigarro. No máximo uma 'associação' de princípios ativos, em baixas dosagens. Faz parte.

Google Translate (may not be 100% accurate):

These 'amphetamines' really do great damage when taken abusively. The head is like a 'Swiss cheese', 3 days and 3 nights without food and feed, and willing to 'give and sell'. It's all a matter of patience, until I find the right remedy, whether it's an 'antidepressant-anxiolytic' combination (mood stabilizers), to me it's a legend. Everything is monotonous and without the least grace. It is' placebo effect '. In the first few times, amphetamines look like an' injection of Happiness, even 1 tablet only. Hence, 'repeated use' and almost continuous, it is difficult to avoid. It really seems to 'open your head', for a well-being. In time we go back to the good old 'rice and beans', a glass of juice, or water, 1 coffee and a cigarette. At most an 'association' of active principles, at low dosages. It's part.

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532

Thankyou Nathaniel
I'm looking for some/ any advice on Adderall and reading one angry post after another, I was fast approaching the point of feeling my heartbeat in my head! Your post was like coming into a calm inlet afyer an angry sea.
For everyone else, this is not only the internet, but a site where most people suffer from one health problem or another or MORE than one. So remembering this should help you either to ignore words you KNOW are coming from someone with problems, OR to avoid placing judgment of any kind. Unless, of course, you're a physician.
Bless all of you.

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533

Existem pessoas que apresentam, uma espécie de desequilíbrio químico, a nível funcional, quanto à produção, para mais ou para menos, de substâncias importantes, produzidas dentro do cérebro, e quando não repostas, de um modo complementar, acaba por interferir, de modo negativo,em aspectos como cognição, por exemplo.Assim como uma baixa produção do hormônio Melatonina, pode resultar em intermináveis noites de insônia,o que acaba por repercutir,por 'tabela',em muitos outros aspectos, como a sonolência diurna 'compensação',em horário escolar, no trabalho,etc. Acaba por induzir a falta de atenção, no aprendizado,e por aí vai.Nestas condições,é preciso repor, seja através do próprio hormônio Melatonina, sintetizados artificialmente em laboratórios,ou por 'outros compostos', para regularizar o sono,levando-se sempre em conta,o fator risco-benefício,dos princípio-ativos,que venham a serem administrados, levando-se em conta as peculiaridades de cada indivíduo,como idade,grau de toxicidade hepática e (ou) neurológicas, entre outros.Isto vale, a meu ver,para 'todos os órgãos',envolvidos no metabolismo das referidas substância. Fitoterápicos,que induzem ao sono, como o Mulungu, a Valeriana, a Passiflora 'extratos', o extrato de Kavaína,obtido a partir da planta Kawa-Kawa,e a associação de 2 ou mais,destas substâncias,podem serem úteis para alguns 'indivíduos',e nem tanto para outros. Claro que a preferência por 'princípios ativos' que,usualmente não venham a provocarem uma dependência,seja psicológica e (ou) física, devem serem priorizados,a meu ver.Contanto que reagimos de maneira diferente a uma mesma substância,sejam elas naturais ou artificiais,além de outras condições orgânicas,que variam de pessoa para pessoa,nem sempre se acerta, na ou nas primeiras tentativas,quanto à escolha de tal ou qual substância.Em tese, penso que isto vale para todos as substâncias, variando apenas quanto à sintomatologia manifestada.

Google Translate (may not be 100% accurate):

There are people who exhibit a kind of chemical imbalance at the functional level as to the production, more or less, of important substances produced within the brain, and when they are not replaced in a complementary way, negative, in aspects such as cognition, for example. Like a low production of the hormone Melatonin, can result in endless nights of insomnia, which ends up repercussion, by 'table', in many other aspects, such as daytime sleepiness 'compensation', in school hours, at work, etc. It ends up by inducing the lack of attention, in learning, and so on. In these conditions, it is necessary to replace, either through the hormone Melatonin itself, artificially synthesized in laboratories, or by 'other compounds', to regularize sleep, taking into account the peculiarities of each individual, such as age, degree of hepatic toxicity and (or) neurological, among others. This is worth, in my view, to 'all organs', involved in the metabolism of said substance. Sleep-inducing herbal remedies such as Mulungu, Valeriana, Passiflora 'extracts', Kavaína extract obtained from the Kawa-Kawa plant, and the association of 2 or more of these substances may be useful for some 'individuals', and not so much to others. Of course, the preference for 'active principles' that usually do not provoke a dependence, be it psychological or (or) physical, should be prioritized, in my view. While we react differently to the same substance, whether natural or artificial conditions, and other organic conditions, which vary from person to person, are not always correct, in the first or the first attempts, as to the choice of this or that substance. In theory, I think this applies to all substances, varying only to the manifested symptomatology.

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534

IQ is commonly observed as a order of magnitude from the norm. Nobody ever interprets the value numerically, i.e. 100 is 50th percentile, 135 is 97th percentile. So 3x is often the case.

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535

I feel this post is strictly opinionated. Theses medications are used daily to help others experience a natural thought process and way of living, not to get a high or energy boost off of. I have struggled with ADHD most of my childhood into my adulthood without knowing and trying to cope with my ways of thinking and living on my own. I strongly encourage anyone who struggles daily to accomplish tasks, struggles with high anxiety or being completely overwelmed by some of life's smallest challenges to be evaluated for this medication. If this medication is used properly then nothing should ever come of it in terms of abuse. Therefor using this daily and not getting off of it would not ever strike and addition problem. All inputs are appreciated, but unless you struggle with ADD or ADHD, keep your thoughts quiet.

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536

Really? that's simply ONLY your opinion. And, are you a M.D? just because you have had issues with it (stating what you wrote) doesn't mean everyone does. I'm sorry you're an addict. however, I am not. And need this medication. So please, less personal information and more medical facts please.

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537

Thank you, I couldn't have said it any better myself. I too am prescribed adderall and its changed my entire life for the positive. I'm now a functional human being. It's such a blessing. And, also a curse because everybody wants them to feel high. It's sad.

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538

I agree with you! I lost my insurance coverage and when I asked the pharmacy if there was a generic for adderall xr they said no but when I got my script filled it was a generic. I've been taking it since Monday and have noticed a huge difference in the way I feel! I'll be calling my Dr Monday morning.

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539

Have you tried the BraMD? Or is this just from what has been posted? Most people will talk when they dislike something. It's human nature to Gabb a complaint. For every complaintime it takes 10-20 positives to counter it. Restaurant reviews, relationship arguments and so on. NOT saying this isn't a valid fact for many. My question is have you tried the brand..also have you tried the xr brand or generic?. KEEP A log ( daily diary) of the same activities while on both and see what works best. Diet and water intake play a part as well. Remember everyday will be different as it's always been.a pill doesn't give us a steady consistent life. All of us have good days,blah days,productive days and unproductive.ADHD mess are a tool in our tool box .Sometimes we need a different tool. ;)

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540

Sais de Anfetaminas, como eu conheço, são Derivados da Anfetamina. Dietilpropiona, Metanfetamina, Dexanfetamina, Dexedrina, Desoxifedrina, Dexanfetamina, Fenproporex, dentre outros, que não me recordo o nome 'princípio ativo'. Diferem, sob a forma farmacêutica, na extensão e intensidade de 'efeitos',para cada cápsula ou comprimido. Todos eles tem em comum; inibição ou anulação de sensação fome e sono.Todos são 'inibidores do apetite', provocam insônia, estimulação cerebral, algum efeito 'anti-depressivo' imediato,e na supressão ou suspensão do uso, fraqueza muscular, ansiedade, depressão,desinteresse, fadiga,e irritabilidade, em certos indivíduos, porém não em sua maioria. Foram proibidos no Brasil,e consideradas 'drogas ilícitas', por várias décadas, ficando somente a 'anfepramona' (dietilpropiona), e o Fenproporex. A cerca de 3 ou 4 anos,também foram estas duas últimas substâncias, retiradas do Comércio, e não autorizadas pelos 'Órgãos de Controle' da Saúde. Recentemente, foi novamente autorizadas, porém a 'altos custos' a 'WENWANSE' (dimesilato de Lisdexanfetamina), assim como a Ritalina, que não chegou a ser proibida, para o tratamento de Hiperatividade, e Déficit de Atenção. Me parece que também em 'off label', como coadjuvantes em dietas de emagrecimento, também. Nunca os tomei, portanto não posso avaliar,embora os ecxipientes 'ingredientes inativos',não provocam nenhuma 'ação' no organismo diretamente, mas tem uma grande importância, quanto ao 'tempo de início',espaço de tempo, em que começam a agirem a liberação do princípio ativo.Existem as 'formulações simples', de liberação imediata 20 a 60 minutos,para começarem a agir, assim como as formulações 'RETARD',ou Liberação gradativa, em que normalmente são em doses maiores 'por cápsula ou comprimidos', porém a absorção é mai lenta, e de maior duração, sendo, inclusive, menos tóxicas, a princípio,exatamente pelo fato de não provocarem a euforia e 'bem-estar', exagerados, assim como taquicardia, em muitas pessoas.No 'dia seguinte',somente uma 'nova dose', faz com que se 'sinta o chão',novamente, fato bastante comum,quando em uso de 'anfetamínicos', de forma contínua; isto também ocorre com inúmeras outras substancias,que possuem o 'potencial' de abuso e a formação de dependência, por provocar um certo 'bem-estar'. Com 'Opiáceos', é a mesma coisa, embora os efeitos, sejam, opostos e antagonistas às anfetaminas, porém o potencial de 'abuso e dependência', são comprovadamente, maiores,devido a também 'sensação euforia',e sonolência leve,assim como a sensação de 'plenitude' e calmaria; sejam as vias de administração oral, retal, I.M (injeções) e E.V., intra-musculares e endovenosas,mais comumente, apesar de também, no caso de certos 'anfetamínicos', via inalações, como administração intranasal, e como 'analgesia complementar' à ação de 'Opiáceos', quando aplicados de forma concomitante.

Google Translate (may not be 100% accurate):

Amphetamine salts, as I know them, are Amphetamine Derivatives. Diethylpropion, Methamphetamine, Dexamfetamine, Dexedrine, Deoxifedrine, Dexamfetamine, Fenproporex, among others, I do not remember the name 'active principle'. They differ, in pharmaceutical form, in the extent and intensity of 'effects', for each capsule or tablet. They all have in common; inhibition or suppression of hunger and sleep.All are 'appetite suppressants', induce insomnia, brain stimulation, some immediate 'anti-depressant' effect, and suppression or discontinuation of use, muscle weakness, anxiety, depression, disinterest, fatigue , and irritability, in certain individuals, but not in the majority. They were banned in Brazil and considered 'illicit drugs' for several decades, leaving only 'amfepramone' (diethylpropione), and Fenproporex. About 3 or 4 years ago, these last two substances were withdrawn from the Trade and not authorized by the Health Control Bodies. Recently, WENWANSE (dimesylate Lisdexamphetamine), as well as Ritalin, which has not been banned, for the treatment of Hyperactivity, and Attention Deficit. It seems to me also on 'off label', as aids in weight loss diets, too. I have never taken them, so I can not evaluate them, although the ecxipientes 'inactive ingredients' do not provoke any 'action' in the organism directly, but it has a great importance, as for the 'beginning time', time period, in which they begin to act the release of the active principle. There are 'simple formulations', immediate release 20 to 60 minutes, to begin acting, as well as the 'RETARD' or 'Gradual Release' formulations, which are usually in larger doses per capsule or tablets but the absorption is slower, and longer in duration, and even less toxic at first, precisely because they do not cause exaggerated euphoria and 'well-being', as well as tachycardia in many people. 'next day', only a 'new dose', makes the 'feel the ground', again, quite common fact, when in use of 'amphetamines', continuously; this also occurs with numerous other substances, which possess the 'potential' of abuse and the formation of dependence, for provoking a certain 'well-being'. With 'opiates', it is the same, although the effects, both opposites and antagonists to amphetamines, but the potential for 'abuse and dependence', are proven to be greater, due to also 'euphoria', and mild drowsiness, as well like the feeling of 'fullness' and calm; are the routes of oral, rectal, IM (injections) and EV, intramuscular and intravenous, more commonly, although also in the case of certain 'amphetamines', via inhalations, as intranasal administration, and as 'complementary analgesia' to the action of 'Opiates' when applied concomitantly.

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