Contrave And Suboxone (Page 2) (Top voted first)

I started today with my first dose of contrave, 1 pill in the AM. I also take suboxone 8mg (4 1 time a day). My doctor stated that the interaction of the two should be minimal..yeah NO! I got diarrhea, hot flashes, chills, body aches, and pretty much every withdrawal symptom known to man. I now dont want to take the contrave because I am not ready to stop the suboxone. Should I just stop the contrave and continue the sub? Or how should I go about this?

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Re: brandi (# 46)

No! Do not take these together, as it will put u into precipitated withdrawal! I did this -terrible! I even had seizures - felt terrible for 12 hours - do not, I repeat, do not take contrave and suboxone together!

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Re: Mandy (# 49)

For the same reason there is so much confusion within this thread.

The words look alike and we’re humans... seems like another case for automation/AI, but seriously prescribing a mu opioid receptor ANTagonist (naltrexone via contrave) with a mu opioid receptor partial agonist (buprenorphine in subs) is absolutely wild. Like I know people with 2-year certificates that would’ve caught that and with all our innovation you’d think we could create a database of contraindicated medications. You know just in case reading the active ingredient becomes too much of a chore.

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Re: Ben (# 54)

Are you on a stimulant? That wall of text doe! Lmao this is a thread on the contraindications between MOR (my opioid receptor) agonists and antagonists. Thanks for the confessional.. honestly didn’t read it because when people need to be that long winded they’re usually not sure that what they’re saying is accurate. Condense and repost? I don’t wanna get lost thinking “what’s this guy on about?” and would appreciate some clarity as to what your ramble (pls don’t get butthurt .. u know u rambled) means in the context of the contraindicated medications? Let’s help people not just please ourselves w comment rants lmao ... oh I guess this could be a rant too? Aren’t we funny lil hypocritical things when we get to feelin prideful?

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How about subutex and contrave? Would they be compatible?

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I've been off contrave for about a month do I start all over or continue with the 2 in the morning and 2 in the evening

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Dexedrine is a stimulant .. It is amphetamine, just not racemic like adderall. Dexedrine only contains the dextroamphetamine (this is supposedly the more euphoric less jittery isomer but who knows). Contrave blocks the reuptake of dopamine and norepinephrine in the synapse and therefore allows for a stronger/longer electrical signal to be experiences at the synapse. Dexedrine also does this, as well as releasing dopamine and norepinephrine. This alone could cause intense anxiety. You're on a lot of things that tweak anxiety, klonopins and amphetamines.. in somewhat of an opposite fashion (for these two specifically).. just talk to your doctor and keep toughin it out cuz you're doing good

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Re: Susie (# 6)

They are not the same suboxone contains buprenorphine which is a partial agonist and alternative to methadone but only activates the opiate receptors enough to keep people feeling "normal" as they try to get off opiates but it does block full agonist opiates to an extent it can be broken through but has a 36 hour half life so it takes a lot more to break through. The other ingredient in suboxone is naloxone not naltrexone and is not absorbed very much in sublingual former and really doesn't do squat. But if you give someone who is overdosing either suboxone or naltrexone (which is what most paramedics will use) it will help keep them from dying and send into immediate withdrawals. Contrave contains naltrexone and bupropion an anti depressant.

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Re: Jm (# 40)

No, buprenorphine is not an opiate. It attaches to the receptors but is not classified to be used for pain management. Also, there is no reason to "lawyer up" and sue because of acute withdrawal. Everyone is out for money in today's world and we wonder why healthcare is so expensive. Should the two be taken together? No but that doesn't mean you should file a frivolous legal case against a doctor. The Contrave is a weight loss med that is completely ELECTIVE and no one has to take it to survive. Also, she should have read the prescription insert from the pharmacy BEFORE taking any new medication. It clearly states the two should not be combined. A patient is responsible for their own health. A simple phone call to the doctor prescribing the Contrave would have remedied this. It's quite likely they didn't know she was on suboxone considering a special license is required to prescribe that drug.

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Re: Pay attention to labels (# 41)

I realize there are 2 medications in Suboxone. And people, Suboxone IS Listed as an Opioid. People say it won't turn up in a U/A, but it will as an Opioid. I don't want to say anything bad about Suboxone, it did help me for about 2yrs. I started on 4 strips a day then I worked my way down to 2 a day. But now, when I tried to get OFF it I weighed 115lbs. (5) FIVE days later I weighed 99lbs. I truly thought I was going to DIE. So my point is, WHY do these people keep coming up with drugs to replace pain meds and the drugs they are coming up with are BY FAR WORSE than the ones we started with? I just don't get it...

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Re: Susie (# 6)

They r totally 2 different drugs!!!!! They are not the same meds...it looks like they are but they truly arnt...

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Re: Dweeb (# 9)

YES! I've heard Dr.'s even get this way wrong. The Noloxone in subs is inactive sublingually! It's NOT the same as Naltrexone which is highly absorbable via gastrointestinal tract. Noloxone on the other hand is in Subs to PREVENT THE MISUSE OF THE BUPE BY ACTIVATING IF OR WHEN INJECTED INTRAVENOUSLY. So, in short, the Noloxone added to suboxone is a safety feature/torture feature if you will to discourage and make impossible it's misuse unlike SUBUTEX or buperenorphrene itself. Again, even doctors get these two similar yet different ingredients confused. Again, Noloxone is essentially Inert in its Sublingual form. NALTREXONE oth is nearly completely absorbable via the digestive tract. Not this, I do t know how this misinformation can be so pervasive considering the extra DEA license to Rx suboxone, but whadyagonnado?

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I have been trying to get off Suboxone for a year. I have gotten down to 1/8th of a 2 mg strip daily. Question: Will Contrave help me to finally get off Suboxone for good? I also take 150 mg of Wellbutrin daily.

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Re: Kevin (# 12)
Subutex is buprenorphine alone. Suboxone is buprenorphine with naloxone. Buprenorphine is an opiate. So if you take Contrave you will go into withdrawal because the naltrexone in the Contrave will block the opioid receptors in your body and the buprenorphine in your Subutex will not be absorbed.

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Re: Dweeb (# 10)

I’m glad someone finally said this! I ended up here bc I was curious if I could take Contrave as I am already on Suboxone and am not at a place of getting off of it yet. The first thing I noticed was the medications combined in Contrave (naltrexone/bupropion) were very similar BUT still NOT the same as the medication combination in Suboxone (Naloxone/Bupronorphine). So I wanted to research the difference before going any further. After looking up both medications used in Contrave I grew more concerned about the possible contradictions in the two taken together. So I search using Contrave with Suboxone and was brought here. I was reading all the comments yet thinking, but they are NOT the same ingredients in both. Why is everyone saying that? So I was glad to come across your comment. Thank you for being diligent and paying attention to detail so you can help inform people and hopefully keep many others from making the not so difficult to make mistake of seeing those ingredient names and thinking “oh it’s the same as Suboxone” when in fact a few letters changed in each make all the difference in the world. Also, as precipitated withdrawals are the WORST experience I’ve ever been through. So much more intense and painful than the already immensely horrible regular opioid withdrawal. Thanks again for being the one to point out this difference for people!

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Hello, Kiat! How are you? I'm very sorry about what happened.

Yes, the Naltrexone in Contrave can cause you to go into withdrawal from any opiate, as listed by the FDA, and you were doubling it up with the Naloxone in the Suboxone that does that same thing.

As to how to continue, it usually takes about 3 days, before you can safely take an opiate, again. Unless your doctor instructs otherwise.

Is there anything else I can help with?

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I am currently on Suboxone due to opioid addiction. I do not plan to take the Suboxone while I am on Contrave, but I am curious if you can tell me in lay terms, what happens to a person who takes both at the same time? Thank you.

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She has to take the opiate and only that. Only take the pain pills. Call the Dr. too.

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They block each other which causes withdrawal because the ingredient in suboxone has narcotic a very powerful one even if they its a analgesic

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Does contrave give you blurred vision if so why And how long before it stops

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I started contrave while on suboxone and was thrown into instant withdrawal. I felt like I was dying from 4pm to 7am when I took my suboxone again.

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