Bendectin And Birth Defects (Page 31) (Top voted first)

I took this drug in the 1970's while pregnant. Am looking for the side effects to the babies. Drug has been off the market for many years. Not sure on correct spelling. Used for nausea and vomiting during pregnancy. Thank you for any help you can send me. Sincerely, Dana.

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REPORT

I took bendictine with my second pregnancy. My daughter had projectile vomiting when she was first born. She has recently learned that she has some kind of heart condition. I am wondering if this can be attributed to the nausea medication. I took this medication in 1976.

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Dee, This is good stuff. For starters you reference Staples (animal) studies, but there is no citation in the birthdefects.org paper, so it can't be reviewed and was likely never peer reviewed nor published. None-the-less, if you're going to lean on Staples then understand that he reported possible teratogenic effects. A teratogen is a substance that interferes with fetal development. You yourself reported that you were "fully developed" when your mother took the medication, and you report that your children have the same issues despite the fact that they were never exposed to the medication. In essence you have presented evidence to refute your own belief (emphasis on belief, no supported science to back it up, see my earlier post on birthdefects.org papers). Something that continues across generations is more likely to be genetic or some long term exposure (assuming you live in the same area in which you were born).

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It's amazing what some putative medical specialists will do to earn themselves a few extra easy shekels. I wonder how many of them are fully-paid-up members with Actors Equity.

eurekalert.org/pub_releases/2015-07/sumc-ptf071415.php

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Alexa, you see. The pharmaceutical industry is so big it can't be touched. It would take someone to spend decades of studying and search out all the victims, get their stories, etc and bring it to a lawyer. Like Erin Brockivech with the legal case of BG & E did. Or someone that concerned with the victims of benedctin. It is unfair. But now days many many people have been made victims and have screwed up lives due to crappy FDA approvals. They have approved it for use again. And when their side effects again shows its ugly horns of never ending symptoms of defects there will be some refuge and compensations hopefully. I would like to live long enough to see that too. I've suffered depression and other ailments from it. My first daughter has suffered from mal formed feet and miscarriages. And now we suspect my grandson, his girlfriend lost one. They broke up and his second girlfriend lost two. It may be a never ending thing for the genes of the people involved too. Besides my daughters malformed feet, all of her children had to have foot surgery because they too had no arches. No one before her in the family had any arch problems. There is proof if they look for it. But I believe it is a skilled cover up. But with this greedy action and the FDA recent approval the can of words is opening again. Like a Pandora's box of proof. It's just sad that uninformed people will again become victims of this drug. God help is all.

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Emtridoc
What a crock. Back up some of your so called proof by posting some well acclaimed copies of documents or studies or even websites. Who's paying you to cut down everyone that posts on here that wonders about if they are victims. You claim and say many things but so far I see no proof of anything you claim. All you seem to be is wasting time trying to discourage people that they would have a claim, if one was ever suspected. You say club foot is rare. Well explain it with documented oroof. How can my daughter have club feet all her kids have flat feet and between her and her kids there has been so far 8 miscarriages. If you can't post the real documented proof don't bother writing a bunch of crock that you hope will alter my suspicions. Its your waste if time.

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Lindy, You're kidding, right?? I'm the only one who has posted citations to peer reviewed literature and numerous scientific studies. Did you even bother looking up the citations?? About the only thing posted to support any claims here are from the website "birthdefects.org" which I showed were largely debunked and in some cases shown to be based on fraudulent data much like the study that was used to try and bring legal cases against vaccines. If you want to read the citations you need only look through my posts. Or you can go to the American or Canadian Colleges of Obestrics and Gynecology which have reviewed the large body of science on the topic and concluded that there is no support for the claim that bendictine is linked to birth defects.

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Same here in 1979,my little boy was born with partial cleft lip

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Ruthe, I've reported this many times, but I know it's hard to search through all these posts, so here you go again: My only "stake" is to bring some science and reality check to this discussion. While you don't explicitly suggest I have some financial stake here, many have made that claim with no basis. I could just as easily suggest that all those who start or end with "we should bring a legal suit" are really seeking financial gain. As for thalidomide, not sure where you think I "defend" it, but again, no basis. Thalidomide is clearly a teratogen, no question asked. What I have pointed out is that a number of people have tried to cite papers or articles about thalidomide and somehow claim that they make the case against bendictine. They don't. They make the case against thalidomide, which is moot.

Finally, I can't quite tell if you're suggesting that the cleft palate in your grandchildren is a result of the bendictine you took with your daughter, but certainly several recent posts have (see Lindy's and others). This would suggest a lack of understanding of what a teratogen is and how they impact fetal development. Instead of supporting a claim that the medication is a teratogen, it instead suggests an ongoing exposure (soil, water, etc) or more likely, a genetic cause that is inherited.

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I was living in Singapore in 1973.& took this for morning sickness. My daughter was diagnosed with billery artresia ( the tubes in her liver didn't develope) at 8 weeks we flew home to great ormond street for an exploratory op sadly at nine months she died. Finally I think I found the answer.

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I took bendectin in 1973 and again in 1977 for extreme morning sickness. I lived in Alaska and was very naive to most things in life such as drugs. My doctor prescribed bendectin so I trusted he was encouraging me to take a safe medication.
This is the first time I have read and even thought about bendectin......41 years later.
Both of my adult daughters have back problems. Scoliosis and severe flexible spine. It seems odd that both have very weak bones

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I, too took this drug for morning sickness for my pregnancies in 1970, 1972 and 1975. My first two were sons and seem to have had no serious health issues. In 1975 I had twin girls. One of my daughters was born with mal-rotation of the bowel, which was corrected with surgery when she was 8 days old. At three months it was discovered she a hernia in her lower abdominal area. Later she had a second hernia in her upper body. Tragically, she died in a freak accident in her home when she was 34. I always thought about these issues because they were developmental and I took this drug. Her twin sister has suffered from endometriosis all of her life since puberty and is now being evaluated for MS.

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I have long wondered whether the Bendectin I took for all 9 months of my 1970, has anything to do with my sons large cavernous hemangioma.

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go to birth defects for children talk to betty mecdeci

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I am a victim of this medicine as well. First I had to have kidney surgery. Then I had to have major female operations.... Last was a hysterectomy at 24. Now I'm 36 and trying to get on my feet after finally getting my degrees and I'm being told I may only have till 40 to adopt. This is upsetting to me for obvious reasons but also bc me and my husband are both only children. I didn't want someone else to have a child for me. I'd rather adopt. I'm also having other health issues that's more recent than 12 years ago that I believe is related to the meds. I am looking to see if anyone knows if it's possible to still sue? This is is ridiculous. If you know of anyone who has an open case I can join or someone who's willing to take the case, please email me {edited for privacy}.

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Just happened upon an advertisement in an Obstetrics magazine for a drug called Diclegis. Reading further, i noticed that it was just a renewed version of Bendectin, containing 10mg of doxylamine and 10mg of pyridoxine. I specifically looked for any mention of teratogenic studies done, and found a paragraph in fine print that stated clinical trials done between 1963 and 1991 showed no significant evidence of birth defects, in both the pills containing dicyclomine, and those without it. One thing i'd like to know is whether my mother's prescription contained dicyclomine or not.

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My nom also took Bendectin while pg with me. I to was born with defects on my left hand. I also hv many other unexplained health problems. If u don't mind me asking, What is the defect you were born with? I am missing my thumb on my left hand.

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Dear MM, I'm not sure to whom you're addressing your question but I was born here in Australia with unilateral *microtia* and *aural atresia*, which means that I've never been able to hear on my right hand side. As to whether Debendox [Bendectin] caused my congenital deformities I do not know, although I do have some long-held suspicions, and I remain ever vigilant for any evidence that might prove Debendox [Bendectin] to be in some way teratogenic, which of course means that I'm no orphan.

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I too remain vigilant for a causal link, even if just for piece of mind...Would be nice to have an answer for my mom, who feels awful that she took something that possibly caused me skeletal deformities and adrenal/CNS issues...Honestly, unless a new chapter of unfortunate events is unveiled with the current Diclegis, I don't see any answers on the horizon.

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I was born in 1981 and my mom took this drug with me and my siblings. But with me she took what they thought was the max safe dosage. I was born with an ear deformity which my parents paid out of pocket to fix because it was considered cosmetic. At age 19 though I found out I had malroation of the small GI tract and they were herniated. And now at 34 I am going in for an mri to check for chari malformation which could be yet another defect. I dont know if these are all related to the drug but I dont think its a coincidence. Did you hear its back on the market?

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I had nine months of debilitating morning sickness and was prescribed Benedictine in 1979. My daughter was a very colicky baby. Actually cried every day all day for the first two years of her life. When she turned three, she would not let me hold her, and literally would push me away. She was angry most of the time throughout her childhood. She was diagnosed with ADD and Oppositional Personality Disorder. Her teen years were incredibly difficult, and she had severe depression. Now she is in her mid thirties, and has been diagnosed with Borderline Personality Disorder. I believe that Benedictine is probably the reason for her disabilities and mood disorders. Anyone else have children with BPD after taking Benedictine during pregnancy?

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