Bendectin And Birth Defects (Page 11) (Top voted first)

I took this drug in the 1970's while pregnant. Am looking for the side effects to the babies. Drug has been off the market for many years. Not sure on correct spelling. Used for nausea and vomiting during pregnancy. Thank you for any help you can send me. Sincerely, Dana.

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REPORT

I have posted under both my own name, shannie, and my daughter, hannie whom also is a victim of the pill my mother took. She was born with no enamel on her teeth as well. I was under the assumption this was a community forum for people to discuss the drug, not japanese engines for trucks. But surely you have some interest in the topic for some reason so do go on... Ill be checking regularly, can hardly wait for your two cents.

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Cheers emtridoc and shannie/hannie. Yes, I can agree my posts may present tangentially to some folk, who think that once the wagons are circled then anything outside is on its own recall, although any perceived thematic aberration per se is not nearly quite as debilitating as teratogenicity's manifestation.

shannie, you're correct that this forum's for folk's foraging for information about the drug Bendectin/Debendox/Diclectin, although the present paucity of posts makes one wonder! Do ponder though, that, 'sometimes', as proven, the longest way round is the quickest way there, whether one can only hitch a ride in a Japanese-engined truck or not. I humbly request a discount on my having to stump-up 2 whole cents too, c'OZ' I do believe that the Aussie dollar'$ now got the edge on the Greenback! But if you'll kindly hold about several 100ths of a cent in escrow for me, I'll not belabour the point, but a written I.O.U. would be so much the better perhap_s'crip. I've always desired to own something in the State$! It could give me just the leverage I need to start taking Bernanke to task! The word 'scrip' applies equally well to a shareholding in a company [ the US of A too? I can spell Uncle Sam with the best of 'em!] as it does to a medicinal prescription. And from there, it could be just a short step away from our seeing a certain pharmaceutical company's Dow_n and out for the count!

One thing that can't be disputed is that there are people online who're reading these posts very carefully, even if they're deemed to not stay on track or they're unable to read between the lines of comment. 'Vertical' thinking has its place, but so too does that of 'lateral'. Dr Edward de Bono has personally solved many an issue, but it's thought he's done far better, dinted diasporal, by teaching others how to address a problem [which may not really be one as it turns out sometimes!], just like the person who teaches another how to fish instead of just giving him a day's fish-feed. Shades of: "So what's the angle?"

emtridoc, I do favour 'exegesis', and have known for quite a while that it can pay dividends for my fellow folk, even those with a penchant for shooting the messenger, c'OZ' they're predominantly the ones in dire need of succour, as evinced by the vitriol of their hard-hearted h_arm'oury. As regards your perceiving my not evading the question, I can say that I'm ever mindful of it [ and myriad others], given that, I firmly believe that I too am a recipient of teratogenicity, but not to an extent that I'll permit it to consume my every waking moment. I can appreciate that many folk desire quick-fix answers to a problem that's niggling them, but Rome wasn't built in a day. The veritable mentor doesn't give easy answers but instead assists those inquisitive to deepen their questions [c'OZ' there be the answer!], c'OZ' prima facie, the initial question is but the precursor to the floodgate's breaching. There's a lot that the 'enfant terrible' can do to further 'the' cause, than merely persist in being a causation to its conundrum, no question!

Consider this rhetorical question too: What if a drug company was fully cognisant or even only slightly suspicious that their drug was teratogenic and may need to be pulled from the shelves. Rather than pull it immediately [which could, with time's passing, prove teratogenicity beyond all doubt], they decide to -- especially if they knew which particular part was definitively causing the teratogenicity, or even most likely to be the culprit -- just preclude the suspected pernicious part's inclusion to the complement making up the drug, and continue selling it at will. If no one has any of the original drug to provide probative evidence in a court of law, then statistics will show that the now innocuous drug's removal or continued sale to the public doesn't show any worth of litigation [even by the FDA], solely due to the fact that -- and most importantly for said pregnant Mums/Moms and their precious bundles, but nonetheless mercenarily either for said drug company's bottom line -- all, or sufficiently acceptable [by the regulators] perniciousness or teratogenicity has been removed.

Moot point is simply this: How easy is it for research into any subject whatsoever to be corrupted, contaminated, call it what you will, even when the corruption's done completely unwittingly and entirely unintentionally? Now consider the same case except with the perpetrator(s) having fervent and unrelenting endeavour to perform a dastardly but highly remunerative [read: Billion$] task. They might even be in need of a serviceable Japanese-engined truck to haul the filthy lucre away!

We're maintaining a vigil_ante!

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emtridoc, I would like to know who conducted the "meta-analysis" on Bendectin. If it was Dow, then it has very little merit in my eyes.

On a side note, (s)hannie, I wish this forum would be a place to voice our concerns and share our experiences about the drug. Unfortunately, it's an open forum and people are entitled to write whatever they want and the way they want to write it.

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The CEO (Michael Pearson, a former McKinsey & Co consultant) of Canadian company, Valeant Pharmaceuticals, is reported in Stephen Bartholomeusz's column in 'Business Spectator', as saying that, "R&D spending works only for the larger firms and on average R&D spending doesn't produce positive returns." The article also says, "Pearson's philosophy since taking the helm of Valeant in 2008 has been to acquire companies with established drugs and to slash their R&D programs". Begging the question, so why does, or should, any pharmaceutical company bother to undertake diligent R&D, if any of them do so at all, or wish to be even suspected of doing such? Methinks this approach of Pearson's will positively show negative return in the long run. It appears that he's p_un'aware of the ease with which one can get more b_ang'st for their buck_ing the tr_end'game.

Mr Michael Moore, or someone of that ilk, may one day opt to return the vestiges of a prescribed and decidedly-disliked pharmaceutical product to its manufacturing company's CEO. A simple Development such as this could initiate requisite complex Research.

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Togal, I can't agree with the premise of your finale in #160. I posted a somewhat lengthy composition several days ago and it's not yet featured. It may never do so simply c'OZ' its content may rankle a bowdler with an axe to grind. But man is not an island, nor so this forum.

'If by traduction came thy mind,
Our wonder is the less to find
A soul so charming from a stock so good.'
- Dryden

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emtridoc, Just curious, went to the Cochran site and found nothing on Bendictine. Was there a link or something or just a suggestion as to where more info could be found?

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This says it was removed in 83 re; causes birth defects

"In 1983, the FDA-approved drug Bendectine, also used to combat morning sickness, was taken off the market because of lawsuits asserting that it caused birth defects."

Article: FDA's fast-track approval of Makena could backfire on KV
http://www.stltoday.com/ ... article_e4472916-0646-539d-b04a-520756765418.html

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24Char, I will have to pull the source article to find the reference. May take me a few days but I will see if I can track it down.

Shannie, The drug was pulled due to lawsuits alledging birth defects, but none of the suits were won and none of the science supported such a finding.

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;*

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I was born on 1973 and my mother had taken Bendictine everyday of her pregency......I was born with club feet and always walked differently...leaning back from the hips. I was active as a child and into the teen years. In 1995 I was diagnosed with limb girdle muscular dystrophy. I feel that the taking of this drug has caused my problems........

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Vicki, sorry to hear this. Consider joining the Facebook group if you haven't done so already.

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Posters may like to have a relaxing read of "Argument from Ignorance" on Wiki, particularly the section halfway down the page relating to "Absence of Evidence" and its opposite "Evidence of Absence". It's only a matter of the elusive 4th Dimension [Time] before science et al. is able to prove or disprove any link between Bendectin/Debendox/Diclectin and 'Malformations of the Human Foetus' [The term 'Birth Defect' as relates to any teratogenicity caused by a drug is an 'insult' per se to all mankind!]. Time doesn't fly, as is generally said in conversation, it flees, just like a fugitive ["Tempus Fugit" Latin]. So it's just a matter of catch as catch can!

A previous poster was somewhat bemused as to why I made mention about Japanese truck engines on this forum. She may also wonder why [if she reads the above suggested site] adult-sized kangaroos of either gender could or should be expected to be found on the back seat of cars but I can assure you that it is not an uncommon occurrence here in OZ and it can tend to make a body hopping mad too!

The fields of science, like our minds, must always be provided unlimited access to witness and host an envied entry of myriad evidence begging both discovery and succour at Dearth's Door. Most of the aforementioned kangaroos don't gain access to vehicles' back seats through open 'doors of opportunity' but instead that of open 'windows [windscreens] of opportunity' which is brought about by their bodily crashing through them at highway speeds! Many times, the vehicle's drivers and front seat passengers end up joining said kangaroos in the back seat if they don't duck-down quickly enough and aren't wearing their seatbelts. Regardless, quite a few folk never live to tell the tale.

We're maintaining a vigil.

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I took Debendox for a long time in 1974 during my pregnancy. My son was born 2 weeks late he was born with a heart defect and club foot and died after 19 hours.

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You say the causes of birth defects are numerous and not just this anti nausea pill from the makers of agent orange, yes Dow Chemical... True there are many other factors that affect unborn children, so why still in this age of info and the web do we as people and victims of the toxic mad scientists using people as guinea pigs. Why so we continue to buy these products and make billions of dollars while we poison the world for the generations to come?

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Kay, I'm very sorry that you lost your little boy. It saddens me. Thanks for taking the time to post your story concerning the plight of his very brief being in life.

It may come to light that certain mothers with a specific DNA gene should not 'ever' be permitted to take anti-nausea drugs such as Debendox/Bendectin/Diclectin etc. It could even be due to these pregnancies being occasioned by 'fathers' with a specific DNA gene. It may even be a combination of the two and/or if the taking of the anti-nausea drug begins before a certain period of the gestation.

I've no doubt that, in time, a definite causative link between certain anti-nausea drugs and their resultant teratogenic effect will be discovered, and as is usually the case, many other things about procreation will also be discovered along the way, be they so revealed but
serendipitously, as many things are, even though certain people will often attempt to convince others that they knew with absolute certainty about many things well beforehand. It's so easy for one to act upon but a hunch, and chance would be a fine thing!

Although meta-analyses may have been carried out with all due diligence by some very talented and dedicated persons who've made the endeavour their life's work, it is so very easy, per myriad reasons, for someone to miss a particular clue during their investigations, particularly if someone else, or more particularly, a business with a pecuniary interest, deliberately or otherwise, does something to corrupt the investigative process.

We're still maintaining that 'vigil'. Although there appears nothing wrong with it per se, methinks it still needs seeing to!

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My son was born in 74. during my preganancy i was sick actully vomiting, if I did not take this Bendetine. I had to take it for the whole nine months. I took the last one the night I went to the hospital to give birth. My son from 18 months had a bad temper . if he got mad he would hold his breath and pass out. one night we stood over night with him at the hospital because when he passed out he hit his head on thew floor and sustained a concussion. My mom gave him a nick name little tiger. He quit high school at sixteen he just could not go by the rules, But he had the greatest disposition if he wasn't mad. At ninteen he got married had a baby girl,just before this his ex girlfriend was pregnant , He has two beautiful daughters and he is the greatest dad to them. They are six monthes apart. His marraige of eight years endinfg in divorce. He was later diagnosed with a very severe form of Bipolar disorder. Now at the age of 33 he has spinel stenosis, myolpithy arthritis all in his spine. he has had one surgery in Boston. His symptoms are getting worse and may need another surgry. He also has to sleep with a breathing machine.He walks with a cane. the dr. in Boston had said that he could have been born with a narrow spinal colume. I just remembered about the Benedectine, that I took for my whole pregnancy and each time he gave me another RX I asked the Dr. if this was safe and he told me yes, My son may be parlized confined to a wheel chair he's only 33, how could they allow this to happen? its all for money. does any one else have a similer story. I am going to look into sueing these money hungry pharmacutical co.

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I took debendox for seven months in 1980 while pregnant with my daughter . She is now in hospital with auto immune disease . She has suffered constant health issues which none of my other 3 children have. Would love to know if any research has been done on the long term effects of this drug

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I found a few facts on the los alamos website most of it is previously classified documents and it seems to be the only site with any even close to realistic findings

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I also have a problem with authority and doing what is expected of me. I also was incarcerated. Addictions, and abuse also hold me down. I feel like I am separated from the rest of the world like im just not like 'them'

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http://www.ncbi.nlm.nih.gov/pmc?term=bendectin

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