Active Ingredient(s): Conivaptan Hydrochloride
FDA Approved: * December 29, 2005
Pharm Company: * ASTELLAS
Category: Diuretic

Conivaptan, sold under the brand name Vaprisol, is a non-peptide inhibitor of the receptor for anti-diuretic hormone, also called vasopressin. It was approved in 2004 for hyponatremia (low blood sodium levels). The compound was discovered by Astellas and marked in 2006. The drug is now marketed by Cumberland Pharmaceuticals, Inc. Conivaptan inhibits two of the three subtypes of the vasopressin receptor (V1a and V2). Effectively, it causes iatrogenic nephrogenic diabetes insipidus. Conivaptan... [wikipedia]

* May have multiple approval dates, manufacturers, or labelers.

Dosage List

Vaprisol 20 mg/100ml Intravenous Solution
NDC: 0469-1602
Astellas Pharma Us, Inc.