Stivarga
Active Ingredient(s): RegorafenibFDA Approved: * September 27, 2012
Pharm Company: * BAYER HEALTHCARE PHARMS
Category: Cancer
Regorafenib, sold under the brand name Stivarga among others, is an oral multi-kinase inhibitor developed by Bayer which targets angiogenic, stromal and oncogenic receptor tyrosine kinase (RTK). Regorafenib shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Since 2009 it was studied as a potential treatment option in multiple tumor types.[1] By 2015 it had two US approvals for advanced cancers. Contents 1 Approvals and indications... [wikipedia]
* May have multiple approval dates, manufacturers, or labelers.5 Discussions
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How did this drug, with its horrible side effects and minimal efficacy (6 weeks survival vs placebo), ever get approved?...
1 REPLYMy father is treated for a metastatic colorectal cancer since two years and now he is resistant to all therapeutic, his ...