What Not To Take With Methadone

Hydroxyzine 50mg 4 time daily. Bus par 60 mg daily clonazapam 1mg 3a day melatonin 10mg bedtime. Does any take away the effect of methadone. I am on 244 mg a day due to rapid metabolism. Had, a few peak and trough to determine this. I have gen anxiety disorder and ptsd and fibro. Also medial temporal sclerosis I'm on lamictal for mood. And undocumented seizures. If it wasn't for the methadone treating pain & addiction I would be one miserable person.

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My pain Dr has stopped my care due to a recent panel. I was under contract with this Dr due to being on 5 mg methadone bid.I am also prescribed 1.5 mg klonopin a day. Their reading showed extensive benzodiazepines beyond what 1.5 mg klonopin should be.
My question is: could taking 300mg of benadryl & 10 mg melatonin nightly along with the klonopin cause the diagnostics to show excessive results for benzodiazepines?

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Hello, Hope4autism! How are you?

No, I didn't find anything listing that any of these will reduce the efficacy of Methadone, though you should double check with your doctor to be certain. From what I've found in the databases, most of them will increase sedation, so that would be the biggest problem with taking all of them together.

Hello, Emmy! Wow, I am so very sorry about what happened.

There is actually a very good chance that it was due to the Benadryl! It is actually only approved to be taken in doses of up to 50mgs per dose, spread out over the day, so you were basically overdosing and very high amounts of it have actually been well known to cause false positives or unusual panel levels for benzodiazepines.

Did they know you were taking that much of it each night?

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No they, the Dr didn't know how much benedryl I take. It's just on my med sheet " take As needed" . Plus 10 mg melatonin. I'm waiting to see the actual results. They say that the GCMS TEST can detect exact substances. But thru researching this, I have found cases that the high benedryl mg could show as high benzo use even with this very accurate test. I've tried calling Dr. Talk to him in person to fess up to amount of benedryl& melatonin nightly use. He won't talk to me. There's a patient portal now where can email Dr. But his students/ residents are the ones who answer. I can't lose this Dr. HE IS THE ONLY ONE WHO BELIEVED ME & Did all the testing to find out what the problem was. I don't know what to do now.

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Question... I am on 35 mgs of Methadone daily thru a clinic. (I have a bacterial infection when i get these they are like a boil and fester until it begins to drain,, I've had two in my life and they are painful. ) Last 2x's I was prescribed CIPRO and wondered why I felt like death.. Since I just moved to a new state & new clinic they INFORMED ME that CIPRO EATS the METHADONE so you will go thru withdrawal symptoms,,, My QUESTION IS.. IS KEFLEX or LEVAQUIN SAFE with Methadone ?? Thank u

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