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Sertraline, Fluoxetine, Titration, Ssri

Updated July 27, 2017
J Says:
Wed, July 26, 2017

I have been on sertraline (generic of Zoloft) for ~8 months (? maybe for longer. I don't have the best memory). My current dose is 150 mg, which I've been taking for ~2 months. It's helped my anxiety but not my depression symptoms, so my psychiatrist is switching me to fluoxetine (generic of Prozac). For the first week I'm supposed to take 100 mg of sertraline and 20 mg of fluoxetine; for another week take 50 mg of sertraline and 40 mg of fluoxetine; then just take 60 mg of fluoxetine.

Previously when I've switched SSRIs (with a different psychiatrist) I went completely off one before starting the other. I'm worried about the risks of taking more than one SSRI at once, does this sound dangerous or is it a safe way to switch? Has anyone done a similar thing with two SSRIs?

Thank you!

1 Reply

1
Verwon Says:
Thu, July 27, 2017

Yes, that is often done to switch medications, although some doctors prefer a clean switch, if the medications are similar.

The FDA warns that you may experience nausea, dizziness, headache, dry mouth, mood changes, and weight changes.

How are you doing so far?

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