Prescription Drug Combinations
UpdatedWhat would be the effects of taking hydrocodone, mirtazapine, salsalate, and cyclobenzaprine?
4 Replies
Is it safe for me to be taking 2x 2.5 olanzapine, 2-3 cloral betaine, 8x30mg codeine phosphate, 1x 150mg viepax XL, 2x10mg oxazepam. In a day. I'm having very bad anxiety and difficulty sleeping, mixed with periods of bad depression.
I have recently been on diazepam (which i didnt like), the doctor has taken me off of 20mg temazepam and 30-40mg oxazepam.
I would like to know if the combination I am on now is safe to take together, any ideas??
thanks
Hi Nic,
There are actually "moderately" unsafe drug interactions found between the following medications:
Cyclobenzaprine + Hydrocodone
Cyclobenzaprine + Mirtazapine
Hydrocodone + Mirtazapine
Meaning that it may be wise to contact your doctor about the possibility of switching these medications to something more compatible. Each of the interactions state the following:
Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.
During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression.
@Simon,
There are also moderately unsafe interactions found between the following medications:
Codeine + Oxazepam
Codeine + Olanzapine
Oxazepam + Olanzapine
The combination of Oxazepam + Olanzapine is highly recommended to be avoided since the safety and efficacy of intramuscular olanzapine administered in combination with benzodiazepines have not been established. Deaths have been reported in patients who received IM olanzapine during postmarketing use; although the cause has not been determined.
I definitely recommend double checking this with your doctor just to be sure that it's safe for you. I hope this information helps!
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