Nuvigil / Methadone Interaction

I have been on methadone for nearly 7 years. I take 45mg daily split into 2 doses. Recently diagnosed with narcolepsy. Was given nuvigil. Within 4 days my methadone started wearing off and within 7-8 hrs I'm in withdrawal. I stopped the nuvigil 3 days ago but still withdrawing 3x a day! How long is this going to last!!?? When will it go back to the way it was? Why don't dr's know about this!?

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Nuvigil can reduce the efficacy of Methadone, so it may cause you to experience withdrawal symptoms. The situation will likely not rectify, until you stop taking the Nuvigil.

The FDA lists withdrawal effects as possibly including nausea, dizziness, rebound pain, anxiety, and diarrhea.

Doctors are not actually required to study medications as much as pharmacists, or pharmacy techs, so they may not know all the possible interactions, or side effects.

Have you informed your doctor of the problem?

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