Nicorandil And Lisinopril,drugs Interaction

Is concominent use of lisinopril contraindicated with nicorandil?

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I cannot post a definite answer for you whether Nicorandil and Lisinopril are contraindicated for one another because Nicorandil is not available in the USA.

I will, however, summarize some details for you below, which may be of help.

First, "Nicorandil acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It does this through two methods. Firstly, by activating potassium channels, and secondly by donating nitric oxide to activate the enzyme guanylate cyclase." [1]

There are a number of types of medication that can interact with Lisinopril. Those include: Diuretics, Nonsteroidal Anti-Inflammatory Drugs, Potassium Supplements, Potassium-Sparing Diuretics, and Lithium. [2]

The only commonality listed for the two drugs above involves Potassium, but it would be best to verify this with your prescribing physician just to be safe. Hope this helps.

Do you have any other questions or information to add? Please post back if you do...

References:

[1] https:/­/­rxchat.com/­wiki/­Nicorandil/­
[2] http:/­/­blood-pressure.emedtv.com/­lisinopril/­lisinopril-drug-interactions-p2.html

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