Depression & Anxiety Resistant To Anti Depressants (Top voted first)

I had depression n anxiety 10yrs ago. Was given Seroxat n had very good results. Been off meds since then. Now depression n anxiety has returned (relapse). Been given Lexapro, Luvox, Prozac. No results at all! Seems resistant to anti depressants. What is happening? Do i go for only benzos to treat anxiety bcos anxiety is main problem not depression. appreciate any help. Thx.

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Hello, Ochomow! How are you?

Have you ever tried just an anxiolytic, like Buspirone, if it's available there?

It may cause side effects, such as nausea, dizziness, somnolence and nervousness.

It's something you may want to talk to your doctor about. It may be what you need if taken with an antidepressant.

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Hope things have gotten better since you posted this. I have depression and anxiety as was adult ADD. I take patil. 10mg of Atavan as needed for the anxiety and to help me sleep when I can't calm my mind, and also Ritalin 10mg 2 times a day. The Ritalin being added really made a difference. I am not wanting to stay in bed. It has helped with my productivity and has helped me focus at work. I know this will not work for everyone but it sure did for me.

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Hello! I came across this forum when my Wellbutrin (bupropion) 450XL a day wasn't working! Yes, 450XL. I am a 30 year old full-time college student and CPhT (Licensed Pharmacy Technician) of 6 years. I was on wellbutrin 150XL and then bumped up to the wellbutrin 300XL once daily to stop smoking. Worked perfectly and lost weight! But I am a student and the wellbutrin 300XL made me feel a little too space to remain organized with 5 classes and work. So I went back down to 150XL and I started taking adderall (don't do that) so I could get through school but that helped very very little. I was slowly going back to the "blah-ness" I had before. So I started taking the 300XL once daily again. Well it didn't work it's magic this time and I couldn't loose the weight again. I stopped smoking but I still had the blues and didn't really enjoy anything. It was terrible!! So........I went to see my doctor. He did blood work and I had almost no Vitamin D and I was Folic Acid deficient. My doctor read the results and put me on Deplin, a medical food aka vitamin if you research. IT SAVED MY LIFE! I take Deplin 15mg, Methyl B-12, Vitamin D and Wellbutrin 300XL. Amazing! I lost my weight again and I'm back to the "happy place" I had when I started the wellbutrin all together! My body wasn't absorbing the nutrition I needed to metabolize and absorb the Wellbutrin. I encourage everyone to talk to their doctor about Deplin! There is a difference between B-12 and Methyl B-12. The chemical structure is different. I take the Methyl B-12 with the Deplin because if you are Vitamin B deficient the Deplin won't do much at all. I did a lot of research before taking anything but I'm SOOOO glad I gave it a shot! Research Deplin (formulated Folic Acid) and Methyl B-12!!

I hope this helps! Good luck to you all!

-- Oh and if anyone has anxiety, research NAC (N-Acetylcysteine). It is a vitamin that relieves anxiety and stress. They even have time-released now. My husband started taking Wellbutrin 300XL and he really benefited from it but he then started to have anxiety so he now takes a time-released NAC in the morning with his Wellbutrin 300XL. He reports no more anxiety :)

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