Brintellix Side Effects Severe (Page 4) (Top voted first)

DESPERATELY NEED HELP ABOUT BRINTELLIX!!! I have been on 5mg Brintellix for last 10 weeks. About 9 days About 9 days ago I started to feel like i was coming down with flu. week progressed and flu like symptoms got worse every day: flushing, feeling like i had high fever but without actual fever, agitation, muscle cramps, bad nausea, diahrrea all day long, fast heart beat, headache, etc. after several days of symptoms getting worse, on Sunday last I had the feeling i was going to DIE!!! worst flu like symptoms and severe anxiety, depression and suicidal thoughts. I skipped the sunday dose and then cut the monday dose down to 2.5mg. it is wednesday, and most of bad symptoms have gone to mild or moderate. Dr thinks i had case of serotonin syndrome n this med. But, no one can explain why side effects started at 9 weeks and not beginning!! Today was better side effect wise, still nausea, diahrrea (but not as bad), agitation, no appetite (cannot eat at all). Here is kicker: dr wants me to take 2.5mg every other day as wants to keep depression and anxiety symptoms down. I am praying to GOD this works! Anyone out there have a similar experience??? I really desperately need help on this !! Please let me know!

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Re: luna (# 62)

To me that sounds like it could be a manic or hypomanic episode and I would share that info with my Dr asap

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Hi! I've been on Trintillex for 7 weeks my intercisial cystitis started to flare up after 2 years is this a coincidence. I am also taking have of a 5 mg. Experimenting myself. I feel agitated today,annoyedas well. Took 5 mg couldn't sleep all night. So lam trying every second day. Unless my IC doesn't go away then lam stopping Trintillex that's it. Hope this helps. Jl

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Great to hear some one out there is taking Trintillex and your taking it every second day. Iam very sensitive to antidepressants so l have to keep to a low dose. As onTrintillex for 7and half weeks couldn't sleep only got 2 to 4 hours sleep. Went off it stopped taking the Trintillex to fast the withdrawal lasted 3 weeks. Was really bad pain every place. Switching to Zoloft or Escitalipram one or the other. Iam going to take the lower dosage try it every second day.and hopefully this will help me. Let me know how your doing on 2.5 mg every second day. Much appreciation and I'll say good good luck to the both of us. Joni

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Forgot to mention l will be speaking to a phychitrist by phone which l had my family doctor arrange for me. Because of the covid he's just doing his first appointment by phone. I really hope he has something to offer me because l do need to talk to him badly.And he specialize in metal health. Take care. Joni

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Re: LKC (# 13)

I went from Cymbalta which did nothing to 10 mg of Trintellix 2x a day. I had an immediate lifting of my depression. About a week later I had itching that was driving me crazy, followed by a rash - individual pimple like bumps on chest and back. These turned into hives and crusty like scabs. I went to Urgent Care on the weekend. Doctor told me to go back to Cymbalta. He gave me a prescription for Hydroxyzine Pamoate 25 mg 4x day. The itching was gone after a couple of days. Hives lasted a few more days. The itching and hives were so bad that it seemed to be an by allergic reaction rather than just a side effect. I have had allergic reactions to two other drugs. I now think I should have tried 5 mg of Trintellix and given it more time. I also had a headache and threw up multiple times each day, i have hardly ever thrown up before in my life. Dr. wants me to try Lexapro. Will try it, but hoping that I can try Trintellix with something for nausea and itching since my depression was so much better.

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On Brintillix 10mg for 4 days now and my head wants to burst! Blood pressure spikes, cant eat cant sleep. Stopped today. Cannot do this....... dont know what to expect.... I also have to take 30mg cymgen at night. I am like a zombie!

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Hi. I have been on Brintellex 5mg for 9 weeks. I imbibe daily with one glass of wine or whisky. I have noticed my heart rate increasing temporarily after the drink, but it passes quite quickly and don't have any other symptoms post the drink. Hope this helps?

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Ssris are a hit and miss. You're truly fortunate if you have a good result. I pray that if you have to take ssris you have a good and fast result. I have been on more ssris than I can count and still suffering from severe anxiety and depression. Psychiatrists can not tell you exactly what the medicine is doing to your brain. I wished they were more knowledgeable about how and what the medicine were doing. I also would like to see more positive post about the use of ssris. I hope all on this forum gets better soon #
s

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I took Brintillex and have discontinued it due to being both anxious and Severely sluggish and tired. More than my usual sluggish and tired self. I also felt hungry even though I kew I was full and gained about 15 lbs, which I haven't been able to get off.

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Sounds like Serotonin Syndrome

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You drink a glass of wiskee a day?? Or wine with your meds? Think that would make u sick and want to puke.

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