Brintellix Side Effects Severe (Page 3)
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DESPERATELY NEED HELP ABOUT BRINTELLIX!!! I have been on 5mg Brintellix for last 10 weeks. About 9 days About 9 days ago I started to feel like i was coming down with flu. week progressed and flu like symptoms got worse every day: flushing, feeling like i had high fever but without actual fever, agitation, muscle cramps, bad nausea, diahrrea all day long, fast heart beat, headache, etc. after several days of symptoms getting worse, on Sunday last I had the feeling i was going to DIE!!! worst flu like symptoms and severe anxiety, depression and suicidal thoughts. I skipped the sunday dose and then cut the monday dose down to 2.5mg. it is wednesday, and most of bad symptoms have gone to mild or moderate. Dr thinks i had case of serotonin syndrome n this med. But, no one can explain why side effects started at 9 weeks and not beginning!! Today was better side effect wise, still nausea, diahrrea (but not as bad), agitation, no appetite (cannot eat at all). Here is kicker: dr wants me to take 2.5mg every other day as wants to keep depression and anxiety symptoms down. I am praying to GOD this works! Anyone out there have a similar experience??? I really desperately need help on this !! Please let me know!

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31

Just starting on 5mg per day as of yesterday. Noticed a difference the very first day! Hopefully the slight itching will subside and it will be what I've been searching for all these years!

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30

I had no idea you couldn't be in klonipin. I was taking both together and gaining weight and sleeping like crazy.

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29

Kds I'm not a doc but I am a seriously seasoned Guinea pig and the jury is just not back on this drug and won't be until 2020. If it hasn't helped your depression or anxiety after 9 weeks and has only increased issues - if it were me - I would be tot rating off drug. Perhaps your doc is having u do that? Every other day sounds like preparation to stop or switch?

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28

I took Brintillex and have discontinued it due to being both anxious and Severely sluggish and tired. More than my usual sluggish and tired self. I also felt hungry even though I kew I was full and gained about 15 lbs, which I haven't been able to get off.

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27

I have been on Brintellix for the past month, taking a 5mg dose. I didn't have too many problems in the beginning. However, my skin has been crawling, and I have literally scratched the hide off the tops of my hands and feet and legs. A week ago, my psychiatrist doubled my dose to 10mg. This is when the severe anxiety and nightmares began. I have been taking it in the evenings around 7pm, and the anxiety is HORRIBLE. I can't relax or calm down, and can't sleep. I'm having fears that I am going crazy. My psychiatrist is on vacation, and I can't keep taking this medication. It has me so terrified, I just want to get off of it and deal with the depression without this added craziness. I already dropped back to the 5mg, but I'm still having severe anxiety, and racing thoughts. One other symptom I'm having is fast/irregular heartbeat. The nausea comes and goes, but I have surprisingly not had real issues in the gastrointestinal area. I hate trying new meds for this reason. I've had better luck with Cymbalta. Once I get through this nightmare, I might consider going back on that, but this experience has me too afraid to try something else new. It's just not worth it. Best of luck to everyone who is on it, or trying to get off!

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26

oops kds - I replied to Pixie - read # 25 it is actually for you - well for all of us who are having severe adverse reactions! Everyone should inform themselves and know when to call P-Doc or quit taking as opposed to riding out some bad side effects. The difference could be as extreme as losing your life when we are all struggling so hard to regain just a decent quality of one. Positive thought and hope for all new testers - keep trying until you get it right.:)

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25

Pixie I have been 300 effexor and tapering off to try brintillix. I also take 300 wellbutrin in the am and topirimate at night for sleep and weight loss(doesn't help either) and trazadone - so 2 days ago yesterday were the only days I took 20 mgs (it's called trintellix here)and . I have tried almost every single anti -d on the market. suffered from MDD and Anxiety since I was 14 and I am in my 40's now and I also thought or hoped this might be the last held hope - but it has been the most painful awful two days on any kind of ssri/snri -or anything else! the worst muscle pain in legs, shoulders, abdominal cramping. It feels like a blood pressure strap tightening around my legs. I looked it up and it sounds like an actual reaction to the drug so I called my on-call doc and she said to stop taking and I will most likely have to go back to "no-effectxor"! I think this drug is not such a good one. the pain is unbearable and not worth risking your life for. Hope this info helps. you should check out the brand site. there it lists side effects and then it lists 'reactions' seperately both severe and mild with instructions.

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24

I thought that too with my Lexapro. 10mg forever. I am thinking after this awful experience I want to go back to that. Talking to PCP on Monday!

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23

I only lasted two 5mg doses. I was sick to my stomach, sweating, shaking, and had a complete panic attack. I haven't had one of those in years. I was on 10mg of Lexapro and have .5mg of xanax for anxiety. This all happened within the last three days. I ended up in urgent care for the panic attack. Will becallcalling PCP on Monday morning. I have never felt so awful in my life. This drug is horrible! Never again! Thank goodness I got samples and didn't spend $ on it! Still don't feel quite right.

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22

I started 10 mg a week ago and have been sick with flu like symptoms for 3 days now:(

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21

I have been on Brintellix for 2.5 weeks. I started w 5 mg, then 10 mg and now 20 mg for the last 1 week. The cognitive shutdown and emotional pain of my depression have improved greatly, much less anguish. However I have a constant stomach ache and sometimes nausea, I had bad diarrhea when I upped the dose to 20mg but it has gotten much better now. Headaches are gone last few days. BUT I think something major is wrong? I have this artificial anxiety that randomly floods me for hours or days frequently, not all the time, but more so than not. I feel very worried and think the worst of everyone. I feel like there's no future for me, no hope. I think this is a change for me for the worse on Brintellix. I am also on 600 mg Li and 2mg Neupro. Advice welcome, I can take Ativan to feel better but it makes me too sleepy. I'm already sleepy with no energy. It's weird to be sleepy and anxious at same time, I don't like this drug. I feel kind of a generalized sick feeling. Anyone else have that? I had some feeling on Rexulti- just ill!!!

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20

You drink a glass of wiskee a day?? Or wine with your meds? Think that would make u sick and want to puke.

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19

I have been on Brintellix since May of 2015. In August started having very itchy dermatitis on my hands (palms) and then on the soles of my feet. These symptoms have grown tremendously to the point that a dermatologist is treating me for psoriasis. Hands and feet are awful. Really thinking this is a drug reaction.

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18

I've been on brintellex for about a month. Light nausea in the beginning. I'm up to 20mg now. I tried taking 10 an 10 today with good results. I have been having horrible nausea and vomiting the last week but today I'm doing good! I guess it's hit or miss with this drug. I also take latuda, remeron for sleep with
Ambien, adderall, and Xanax. I'm hoping that the nausea and vomiting has gone away but I cannot take it on an empty stomach. Seems like 3 pm is a good time. I'm not full from lunch but still have some food in my stomach. I have also had a horrible cold with lots of sinus drainage which could be related to the nausea. Overall, I feel better. I haven't felt this happy and like I have things together in a long time. I was on lexapro for almost 10 years and didn't think it was working anymore. Good luck to everyone and hang in there!

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17

Yes, I have been taking Brintellix 10 mg for six weeks, and have had severe itching, headache almost constantly, bloating weight gain and no energy. I was in hopes that it would be the cure, but am very disappointed. It works great for my sister, though. Everyone is different, and will experience varied side effects.

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16

Brintellix has been wonderful for me. I take it at night. Meds that bother your stomach seem to fair better in the evening. And yes I drink with it quite frequently and it doesn't bother me. Maybe you're still in the adjustment phase. Maybe try eating something on it so your stomach isn't empty. I have gotten very sleepy on it though. Good luck JB

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15

Don't take the Brintellix! It is a living nightmare! You will get sick and think you have the flu! Thought I was going crazy, nausea, diarreah, light headedness, body aches and pains, insomnia, anziety, nightmares, mental instability. I only took it for 3 weeks. That was enough! It took 4 months after discontinuance for all of what I just described to go away! Not even worth trying! Spare yourself.

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14

I have had itching and a slight rash on my wrists and a few fingers. I used a cortizone cream and that really helps with the itching. I have been on 20 mg for 8 weeks.

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13

Has anyone experienced severe itching while taking Brintellix? I am beside myself with severe itching. I'm planning to discontinue as I can't stand this side effect. Just wondering if anyone else experienced that.

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12

Totally agree, worst experience ever for me. I hope you are feeling better

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