Atipam (Top voted first)
Updatedanxiety. round pill small
3 Replies
Sorry, nothing is listed under that name, could you please double check the spelling? Is is possibly Ativan?
Pharmacology of Drug ATIPAM GENERIC-Lorazepam
Mechanism of Action Lorazepam mainly acts on Limbic system and ascending reticular formation in the CNS and it binds to the BZD receptor. The binding will facilitates GABA mediated chloride channel opening and produce hyperpolarisation. This will produce an increase in the concentration of the inhibitory neurotransmitter GABA and chloride ions and decreases firing rate of neurons. These alter normal excitatory functions of the body. Lorazepam is used as adjuncts in anaesthesia for anxiolysis, amnesia and sedation prior to induction of anaesthesia
Pharmaco Kinetics Absorption: It is well absorbed after oral administration Distribution: It is distributed widely in the body. Metabolism: It is metabolised to inactive metabolite in the liver. Excretion: Most metabolites are excreted through urine
Onset Of Action 1 hour
Half Life 10 - 20 hour
Duration Of Action 12 - 24 hour
Adverse Effects 1.Ataxia 2.Drowsiness 3.Lethargy 4.Hallucination 5.Nausea 6.Constipation or diarrhoea 7.Amnesia 8.Dependence 9.Pain at the site of injection 10.Confusion 11.Light headedness 12.Mood changes 13.Muscle cramp 14.Tremor
ContraIndications 1.Hypersensitivity to Benzodiazepines 2.Acute narrow angle glaucoma
Special Precautions 1.Renal impairment 2.Hepatic impairment 3.Myasthenia gravis 4.Pulmonary insufficiency 5.Jaundice
Pregnancy Contraindicated.
Breast Feeding Contraindicated
Old Age Used with caution
Children Below 12 years contraindicated NEONATES- contraindicated
Interactions Alcohol & Other CNS depressants: Enhanced CNS effects. Digoxin: Increase in serum concentration of digoxin. Imipramine & Desipramine: Enhanced activity of these drugs. Levodopa: Decrease in antiparkinsonism efficacy. Oral contraceptives: Decrease efficacy of lorazepam. Theophylline: Antagonises the sedative effect.
Indications 1.Anxiety 2.Preanaesthetic medication 3.Insomnia 4.Anxiety neuroses
Dosage Adult: 2 - 6 mg/day in divided dose Anxiety: 1 - 2 mg 2 - 3 times a day Maximum dose: 10 mg / day Insomnia: 1 - 4 mg at bed time As Antiemetic before chemotherapy: 2.5 mg in the evening ( the day before chemotherapy) and repeat after beginning of the therapy . Anaesthetic-PAM (IM): 0.05 mg / kg body weight given 2 hours before surgery. Children: 0.05mg/kg orally/ parenterally every 4 - 8 hours in a day.
Schedule H
Storage The drug should be kept at room temperature (25 degree C) in a tightly closed container. Keep out of the reach of children
Over Dose Give support and symptomatic treatment. Flumazenil can be given as antagonist. Hypotension can be treated with vasopressors.If the patient is conscious induce emesis followed by charcoal administration.
ive been taking atipam for a few months now and 1 mg per day. I want to stop taking it. I am also taking effexor for anxiety 112 mg. Is this going to be difficult. I dont want my family to know that i am taking atipam. Will the effexor help with stopping the atipam? Thank you i HOPE YOU HAVE SOMETHING COMFORTING FOR ME, I DONT WANT TO TAKE THESE PILLS NO MORE
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