Telaprevir Rash/swelling

I was on telaprevir, on week 5.5 I had to stop the telaprevir. Rash started behind knees and elbows, then took over whole body. Nothing helped. I asked for pred, but they wouldn't prescribe while on triple tx. Stayed on the other 2 meds for 2 more weeks, then swelling of face, legs, arms, chest started. Hurt to walk, and couldn't wear shoes and regular pants because that is how swollen I was. Gained 23 pounds in a week. Nothing helped. Creams were suggested, zyrtec (haha), hydroxyzine (no help). The day before Thanksgiving doctor finally sent me to rheumatologist after running echo, another series of blood tests, etc. The rheumatologist finally prescribed prednisone. Thanksgiving, swelling in face went down enough so I could open my eyes. A month later still suffering with bouts of severe itching, anxiety, and swelling. Doc told me last Thursday (12/15/11) to expect this for a while. They tell me I had a severe reaction to the medication. I tested negative for hcv at week 5 and then again week 9. They are hoping I suffered long enough for it to work. We will see next month when I go back to doc for another series of blood work if it is still negative. Has anyone else had a severe reaction and how did your doc approach it?

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I haven't experienced this, since I do not suffer from this medical condition and have therefore never used these medications.

But, did they have you try anything else to treat the symptoms, such as Benadryl/Diphenhydramine?

That's usually the first go to medication for any type of allergic reaction, as it is usually very effective.

https:/­/­rxchat.com/­wiki/­Diphenhydramine/­

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