Switched From Pristiq To Wellbutrin Xl (Page 3)
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I'm adding a post to hopefully help someone as reading other people's posts has been very helpful/comforting to me! I have been on 50 mg of Pristiq for 5 years and I just made the transition to Wellbutrin xl at 300 mg. My doc switched me because my libido was becoming obsolete and wellbutrin is not supposed to adversely effect this. He had me start by overlapping the two meds for Week 1...Maintaining 50 mg of pristiq and adding Wellbutrin XL at 150 mg. I felt completely fine, didn't notice anything different. Week 2-I was to go up to 300 mg of Wellbutrin XL and completely stop taking the Pristiq. That didn't work. 1.5 days in I was dizzy, minor brain zap feeling (but not as intense as when i would miss a pristiq pill in the past) feeling super emotional (weepy) so much that I had to leave work so I didn't fall apart in front of everyone! I called the doc and he told me to take half a pristiq pill for the next few days. I did that and it really helped and got me thru. The only side effect was minor dizziness at times. So then after a few days, (which was this past Saturday) it was my first day to retry no pristiq and 300 mg Wellbutrin XL.

I made a conscious decision that i would stay in saturday and see how it would effect me. I was dizzy, anxious/fidgety, I had muted brain zaps (again not as bad as simply missing a pristiq pill when that's all I was on) and again had crying spells that would come and go. The thing that got me thru was knowing "this will pass" and it's part of the process. I felt like my head was in the clouds Saturday and Sunday. My head also felt "full" almost like a drowning feeling in my head! Probably the worst part. I'm not sure if that was just my anxiety rearing up. I also woke up in pure sweat (yuck) which has alowly tapered off over the week.

Day 3 with no pristiq (Monday)- I felt like my head was steady again! I felt super relieved. Part of it was the feeling that I made it thru the worst and I could do this. However, I have had intense anxiety all week, almost an exasperated feeling at all times. At night, I would feel my body was tired but my mind couldn't let me sleep. I think the elevates energy brought on anxiety and made my breathing labored. I would definitely recommend staying off caffeine at least in the beginning (you won't need it!!!). I looked up breathing exercises, which reminded me to EXHALE so I could get a good deep breath. Apparent when you're anxiety sometimes you forget to exhale.

This past week has been manageable but tough with the restlessness, lack of sleep, anxiety. Luckily, it hasn't been to the point where anyone visibility noticed at work. If anything, I was working faster, more efficiently, being more direct (no snappy but direct--almost like that sensor that usually causes me to pause and examine what im going to say first was removed--that part has been nice. Like a remov of fear/social anxiety). It's Friday night now- day 7 complete with no pristiq and 300 mg Wellbutrin, and beginning last night, I FINALLY felt a sense of calm. That carried thru to today and I am so grateful. I will post any updates. If you're transitioning with your meds, I strongly recommend you tell loved ones bc it takes a major pressure off and you have a support team. I hope this helps!

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Hi K,

Thank you very much for your input! I'm sure the time you took to write this out will very well help someone who is struggling with switching to Wellbutrin. In fact, I'm sure that it's also inspiring to those who are struggling with withdrawals from other medications. It's great that we can all help each other out in this way!

Does anyone have any questions about Pristiq or Wellbutrin XL? If so, please reply!

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