Seroquel Vs Zyprexa Dosage
UpdatedHi, I've been on 300mg Seroquel 4 years. My pharmacy doesn't have any currently but said they have Zyprexa. Does anyone know what Zyprexa mg equals 300mg of Seroquel ? My doctor is out of town till next week, then I will ask him too. Thank you.
2 Replies
I would confirm with a pharmacist but if I do some math based on the findings in this pubmed article, which states:
Doses equivalent to 100 mg/day of chlorpromazine were 2 mg/day for risperidone, 5 mg/day for olanzapine, 75 mg/day for quetiapine, 60 mg/day for ziprasidone, and 7.5 mg/day for aripiprazole.
So if we take that at face value and assume that 5 mg/day Olanzapine (Zyprexa) is equivalent to 75 mg/day Queiapine (Seroquel):
5 / 75 ~ 0.0667
Therefore, 300 mg Seroquel * 0.0667 ~ 20 mg Zyprexa.
Please note that clinical effects (like sedation, metabolic impact, and receptor binding) vary a lot between these drugs. As such, your doctor or pharmacist may recommend a lower dose of Zyprexa such as 10 mg to get the same therapeutic effect.
Hope this helps!
Re: Roy (# 1)
Thank you very much for that info Roy. Appreciated very much.
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