Setting Record Straight!! How Long After Taking Subutex Can U Take Methadone (Top voted first)

Both subutex and suboxone will cause precipitated withdrawal. It is the bupe that connects to the receptors and kicks the methadone out. Naloxone is just an extra blocker!! I am a social worker at a clinic. Waiting at least 12 hours only if on low dose 20mg or less should b OK. But 24 preferred.

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Why do people always minimize Naloxone? EMTs give the ODs Narcan, which brings the patient into withdrawal. Naltrexone (Vivitrol) has been used with chronic opiate addicts and alcoholics in several forms, pill, 30 day shot, implant. It is a VERY strong blocker and has many side effects. I have personal experience with this medication & know that it is not something to be looked over.

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I have only taken about 8 pills one-a-day 8 milligrams of subutext and they wanted to put me back on the box in which I had a reaction to so now I have to go to a methadone clinic will it be okay to start the methadone after only taking a weeks worth of 8 milligram subutex

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@Original poster,

Thank you for your post. There is a lot of misinformation surrounding the use of opiates/opioids before and/or after subuxone/subutex... and this thread you started does help set the record straight on that end. However, one thing I want to note is that there are many personal patient reviews on other threads here implying that patients should wait several days after having Buprenorphine before taking certain meds like Hydrocodone (as an example) in order to feel its full effects. I'm just thinking that 24hrs is a little short of a wait time considering that Buprenorphine has a half life that's potentially longer than that time frame... Any thoughts on this?

@Niele,

My guess is that Naloxone is often overlooked because Buprenorphine is regarded as a having a higher affinity than Naloxone on the receptors, essentially doing most of the work. Naloxone also has a relatively short half life (of 2-12 hours) compared to Buprenorphine's estimated 24-42 hours half life. Information I've come across also "suggests" that Naloxone is there 'in-part' to deter abuse, since Buprenorphine can obviously do the job on its own (hence Subutex). This is just my opinion. I know others will have a different perspective from personal experience.

Hope this helps!

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I will set the record straight. If you're on a methadone programme and your body is saturated with it, wait 24 hour's at least. If you're on a subutex programme for a few weeks you can take other opiates straight after and feel no withdrawals. It all depends on what drug programme you are taking at the time.

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If you take a little less then half of a 8mg subutext 15 hours ago is it safe to take 20mgs of methadone does anyone know! ! !

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Here is what I am confused about. Subutex, not suboxone with naloxone, is a partial opiate antagonist. If you are going through bad withdraws and take it you will feel better because it binds to your receptors.

However, I hear people say if you are not going through wds and take subutex it will kick the opiates out of your receptors and put you in bad wds. Heres what makes no sense to me, not saying anyone is wrong or anything, if you are not going through wds and take subutex, it makes sense that it will kick the opiates out of your receptors but once the subutex entered the brain and binded to the receptors the person should have no wds right?

Suboxone on the other hand has naloxone, so it makes perfect sense that it would put a person in full wds.

Here is my experience:

I was on methadone a few months ago and I took my dose on a Friday like normal. I missed Saturday and Sunday due to oversleeping. Sunday evening I took 16 mgs on suboxone. I went into wds very badly.

I got off methadone and was clean for a while and started taking opiates like a dummy. One day I was administered opiates intravenously around 7:30 am. Later that day I was given a subutex pill 8mgs and I was feeling no withdraws at all when i took it at 7pm. Ater taking it i felt fine. No withdrawals what so ever.

Everyone is different but my take away from it is the naloxone in the suboxone is why I went into withdrawal so bad. Obviously, the opiates were still in my system when I took the subutex because i felt fine.

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Re: jmd (# 13)

You need to wait. I have experienced precipitated withdrawals, and I have witnessed others have even more severe precipitated withdrawals... and yes in both cases it was from Subutex, not Suboxone (Zubsolv wasn’t even around at that point).

I don’t know why people seem to think that Subutex won’t send you into precip. withdrawals, it most definitely will and trust me you’re not going to like it.

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Im am currently on 8mg of methadone and t only have 2 day supply left, however i do have alot of zubsolv, how long do i have to wait before i can take the zubsolv and how much should i take?

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You are exactly correct my friend !!!!!

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About to set the record straight on this topic since there is no actual proof from someone who has tried it. Will subutex put you into withdrawal taking methadone afterwards? Im going to try it now and find out. Will you feel the methadone taking it after subutex? Ill find that out also. Will you go into withdrawal taking subutex after methadone? Find that out on Saturday. Ive done opiates within a few hours after taking subutex and trust me, you do not go into withdrawal once the bupe has binded to your receptors, the opiates just bounce off them. I have taken bupe after other opioids did not go into withdrawal either. Now, today in a few minutes i am going to take fourty mgs of methadone as my clinic is closed today and tomorrow. Will i feel the methadone? Ill find out but my only concern is i take 20mg of subutex everyday and methadone has a 72 hour half life so saturday ill still have approximately 25-30 mgs of methadone. Ive never gone into withdrawal taking bupe after opiates before.

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How did you get on? i know if you're using subutex for a while and it's bonded to receptors you can take any opiate straight after taking it. But if you do not have subutex in your system (I mean your are not buprenorphine dependent) then you have to wait. Even 22 hours for my friend wasn't enough. He crashed and burned that time so next day tried again (Methadone to Suboxone), this time left it 40 hours which seemed easy as was using gabapentin which helped.

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I took 20mg of methadone 20 hrs ago. Can I take subutex shortly cuz I feeling withdrawal? Thanks.

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I just have a question...I've been taking opiates for about 5 months... I went 14 hours without any and tried to take a 8 MG subutex and felt worse. So I took more opiates and felt a little better but still not good.. How long till I can take a suboxone?

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To the subs to dones ? It is the amount of music daily use 100 hours .so 100 mg of dones and 100 hours is 200 hours. I would urge you to never take subs with less hours then what the math is. I tried to get off dones by my self and had no info on subs. 20 mins later I was in a 3 to 4 day withdrawal. Extremely painfull. Get down to 20 to 40 mg . Get a script for chonidine, it helps and a benzo and go the 4 days , you should be safe

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Im in the hospital and i thought they were taking me off of the dillauid so i took 16mg of subutex so i wouldnt go into withdrawl they decided to keep mebon it and i just got a shot and felt nothing how long will it take for me to feel the dillauid im in a lot of pain. Please help

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Re: jmd (# 13)

I sure as hell did... I didn't have my 90mg dose for two days so I said f*** it, I'm feeling s***ty, I'll take a quarter of an 8mg sub... That was the worst mistake of my life. I went through intense withdrawal for at least 12 hours.

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Re: David (# 3)

I took 4 mgs of Suboxone. Can I take my methadone and feel the effect? It will be about 24 hrs since the subs.

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Im having to change doctors due to insurance issues and also to do with insurance issues there will be a 4 to 5 day period where i wont have any suboxone and i have a family to tend to so i had entended to take 10mg methadone each of those days so how long would i need to wait to start my suboxone or subutex not sure what new dr prescibes?Thank you in advance

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Re: Dave (# 8)

Hi Dave! What ended up happening after you took the Methadone the next day after having Subutex? I'm in the same situation right now. I hope you get this, and are well! Your feedback is much appreciated!!!

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Every person’s system is different. It really depends on how long you have been using a certain other opioid and which one. New study show that a person can be switched from doses of somewhere around 160mg morphine or oxycodone straight to Subutex. My doctor had me stop methadone at 30 mg a day, but take morphine instant release and tramadol. He had me do this for two weeks. I had almost no physical withdrawal symptoms, but the anxiety and depression and insomnia were overwhelming. Xanax, gabapentin, and Zanaflex got me through it. I tapered down On the MSIR to 60 mg a day, and then took only tram at all for 24 hours, then went straight to the Subutex with no problem. Within an hour it felt like the weight of the world has been lifted off of me. I don’t think I needed to wait two weeks but he said that precipitated withdrawal from methadone caused by Suboxone or Subutex will make patients never ever want to take either of them again and on the MSIR to 60 mg a day, and then took only tramadol for 24 hours, then went straight to the Subutex with no problem. Within an hour it felt like the weight of the world has been lifted off of me. I don’t think I needed to wait two weeks but he said that precipitated withdrawal from methadone caused by Suboxone or Subutex will make patients never ever want to take either of them again and can compromise your health and life. So I’m grateful to him because I am feeling 1000% better now

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