Oxycodone/percocet Generics! Which Are Most Effective?
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Hello,

First, let me start by saying that I am somewhat opiate naive. I am not in pain management and hopefully won't need to be. I've had scripts here and there for norco and percocet. It is the generic percocet, or more specifically the oxycodone, i'd like to discuss here.

Over the past year i've had issues (such as a broken elbow, recurring kidney stones, and a staghorn lodged in my renal pelvis [kidney]), that have lead to several prescriptions for percocet from a total of 4 different manufacturers. Mallinckrodt 10/325, Amneal 7/325, Rhodes Pharmacy 10/325, and AuroBindo 10/325.

I've read a lot of reviews about the aforementioned generic manufacturers. The majority of them have been negative especially for Rhodes. Mallinckrodt and AuroBindo are the only two that seem to have, at least, a couple of favourable reviews.

I've got a new script for a week's supply of percocet 10/325. The primary pharmacy that I go to is Kroger (my local CVS carry Rhodes). Kroger carries the U17 Aurobindo which seem to help with pain but cause other issues; tinnitus, anxiety, drowsiness, agitation and at times nausea. Those are things I can deal with but I'd rather not.

Does anyone have any input on what they find to be the best generic manufacturer of oxycodone? I've read about endocet, actavis, watson, kvk, and others but none of them seem to be readily available in my area.

These are what i've tried in order from best to worst:

1. Mallinckrodt - good pain relief, seemingly no side effects, mild euphoria. (Unfortunately I cannot find Mallinckrodt anywhere around my area.)

2. (tie) Amneal/Aurobindo - Kind of a toss up between these two. They seem to work for the pain but have noticeable side effects. Auro (effects listed above) and Amneal both seem to cause anxiety/panic. Profuse sweating and itching have also been experienced with Amneal although not with Auro.

3. Rhodes Pharmaceuticals - I've read some horrible reviews for these. While I don't think they're as bad as some of the reviews, they were definitely very weak compared to the others i've tried. Sort of hit and miss though as one pill would make me feel high and another would make me feel sick (while not doing much for the pain). A plethora of side effects with these as well with malaise and dysphoria; the ultimate worst!

Okay now that you've heard my subjective opinion and rant, can anyone out there offer their opinion on these generic oxycodone/percocet manufacturers. Are there any generic brands I'm missing or never heard of? What's the most effective for killing pain with the least side effects? (I'm taking them for pain).

P.S. I'm going to have to fill at Kroger and get the Auro U17 regardless but would like to know for future reference. Thanks in advance! I'm in the Indianapolis, Indiana area.

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Re: Sam (# 9)

Amneal works for me can't can't find it at a Kroger they are rude and says they only get what the warehouse sends I have e Rhodes really tears up my gut Where can I find Amneal it works much better less side effects

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Re: Herb (# 37)

He is 1000% correct!! Generics are allowed a 20% difference and still pass. The 20% isn't likely to be higher than the brand but if so, still passes.
Take our word, that is the LAW!! 20% difference is exactly correct story!!

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The doctor prescribed me oxycodone HCL‘s 10 mg which help me now they gave me oxycodone 10 mg HRHO‘s they don’t work why

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Re: Mason (# 6)

stay away from camder they are junk

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Re: Mason (# 1)

I went with Mallencroft and they have been okay. Stay away from Camden.

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I'm now on 30mg oxycodone by Mallinckrodt manufacturer that make me very sick. Can anyone suggest a different manufacturer that is better?

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IMHO stay away from CAMBER, pure poison.

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Re: Sparky (# 11)

Order kratom and capsule it. It actually works.

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Re: David (# 7)

Are you taking Rhodes they cause crazy Sciatic nerve pain

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In my last post late last night I failed to complete my thoughts. When oxycodone was reformulated there reasons were to reduce drug liking and addiction. I believe this step was in response to the abuse problems. End result went too far by taking away some of the analgesic powers as well. All forms from brand to generic were affected by changing the main ingredient oxycodone. However this change that was in good faith left a problem. Mallinckrodt at that time made a superior product rated amongst the best. Actavis as well which is difficult to find, so no matter what you choice or what is available still include the same main ingredient. Other companies used an array of binders that don't agree with everyone. So your body chemistry dictates what will work for you. No two people will have the same effect is why there is so many different opinions. So now choosing is a difficult one. Many pharmacies make there choice based on cost, strength and what's best for there customer. When food becomes an issue its not about what you eat as it is when you eat. Hope you find something that will work for you and control your pain, that is what we are talking about!

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I'm reading these comparisons in a new light tonight. Percocet at one time was very effective. There were no generic drugs. Just brand name. They were used for post surgery and most severe pain caused by accidental injuries. The DEA.... is responsible for the reformulated oxycodone to stop drug liking. High doses weren't needed before this whole darn mess with abuse. If oxycodone was returned to it's original formulation you and many other people would not be suffering. This may not be a popular version of why they don't work but it's nothing but the truth!

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All the ones you mentioned are terrible!! It took me a year of suffering with horrible side effects until I tried Endocet. No side effects and good pain relief. I’m on the 7.5/325 right now but will try the 10/325 down the road. Amneal has by far the most complaints with the FDA. Do your research (I’ve been researching for the last year after being given Amneal). I never realized that there was such a huge difference in generics before my bad experience. Horrible pain in my upper stomach for the full 30 days I was stuck with them and NO pain relief. This is true for ALL genetics, not just opiods. Most drugs nowdays are being manufactured in India and China. Who knows what they use for fillers!! Could be plastic. I WILL NOT ACCEPT ANY DRUGS THAT ARE MANUFACTURED IN THOSE COUNTRIES. Like I said ~ do your research. It’s time consuming but worth it.

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I would advise getting a copy of your medical records from your pain clinic ..... i m going out of town so i asked for my records ...... i went back 6-7 months ,,,1 visit every 28 days ..... i cant even tell you how many mistakes i found from not so drastic as family member ailments that i have no idea where that info came from ????? To very serious lack of entering current symptoms ...... IMO THATS INEXCUSABLE SCREW-UP .......... how can dr make a good dicission without proper information ........i better stop here just get your records & make sure they are filled out properly

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Re: ThunderHeart (# 129)

I’ve always thought that the A.M.A., or whomever, would be absolutely sure that, for example, if you get any generic drug it would be mandatory that the exact amount of the active ingredient should be in all generics... I know people that take Diazepam & they insist that the “Roach Brand” is better than all of the many generics that are out there... Maybe it’s all in their heads like the Placebo effect... I don’t know, & how did you determine that there’s less of the active ingredient in the generics, are you a Chemist & tested these drugs you’re referring to!? Please explain ‘cause you can’t go by what someone or even many people tell you...You should have Hard evidence not just hearsay!

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Re: Bravesfan (# 128)

I agree with you!! Ive been trying to get this out to people too!! Generics are NOT effective!! They are filled with more inactive nasty fillers and MUCH LESS of the ingredient that makes it effective!! Im sick of what is happening to the medicine that is supposed to help us!! Ive had so many negative reactions to generics!! Itching, upset stomach, headaches, panic attacks flu-like feeling. There is a war on people with chronic pain because of the people who are abusing opiates!! Why should I suffer because of other people who cant control their actions!! Innocent people suffer because of the ones who abuse. Do the homework!! Check medical histories of people before you through them together with abusers!! There are a lot of us who take medicine responsibly!! Something needs to be done about the lousy quality of medicine being sold to us!! We need a loud voice who will help stop this nastiness of selling us poor quality medicines!!

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Been on Oxycodone and Percocet p!us a long acting narcotic for 20 years and in that timeframe have tried a lot of the generics.

It would seem to me that Activis and Watson worked the best but never received any meds that flat out didn't work.

That is until February of this year my Walgreens changed to Camber.

I was sick within hours of taking them.

Vomiting, terrible stomach pains (not cramps), awful pain and withdrawals thrown in there too.

I was shaking and just plain miserable between what the drug was doing to me and no pain relief at all.

Thought I had the flu til I just happened to see a post about lots of people being sick taking Camber.

Not sure what's in them but I truly felt poisoned.

After a week of misery, my PA at my pain clinic was kind enough to write me a script for hydrocodone to get me thru til I could get my next Percocet script.

They now order Activis for me.

It took me days of being off the Camber to really start feeling better.

From now on I will check any script and will never take anything from Camber again.

From what I have seen, it looks like there are problems with other meds they make.

I have tried to tell my story everywhere I can hoping to save some folks the agony I went thru.

Generics are absolutely not all the same.

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Re: Mason (# 8)

Reason being they all have been on the mild side for a couple months now. Normally they should help. Good luck.

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What about Hydrocodone generic for vicodin? I think it has the least side effects except the fillers must bother me with an allergic reaction of itching me all over! Why can't something be done about this? I know of other people it happens to!

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Re: kdog57 (# 15)

I think the best of them would be Actavis A 215 30 mg EPC. Duel agonist if you can find them. They work mainly through the MU receptor. The brand Roxycodone 30mg are about the same but cost way to much. No feeling of euphoria to speak of after the reformulation. Oh and the antagonist opiate blocker they say isn't there is. They need one or they would be very dangerous. But Naltrexone blocks all the euphoria. Look it up, "Naltrexone".

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Re: ISE (# 111)

I know Brittany Murphy didn’t die of drugs. She had pneumonia. I am legal to smoke and believe it or not THC makes my pain worse. I do like CBD, it is helping a lot, also with anxiety and depression. But it is sad how everyone is being punished who suffer from chronic pain, because of other people who like to abuse drugs! And pain meds! But I am all for pain medicine if you need it.

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