Nucynta Effects (Page 2) (Top voted first)

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Hi there, I am currently taking oxys for my chronic pain, which work very well for me, but my dr has just given me a script for nucynta which is a fairly new drug. Just wondering if anyone has any experience with these and if they can give me any info regarding the effects, if any, side effects etc compared to oxys? Any help would be greatly appreciated. Thx in advance for ur time

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Re: Jimmy (# 2) Expand Referenced Message

Will this medication give you energy? My doctor took me off my hydrocodone 5/325. Which gave me at least some energy. Will the nucynta give me energy? Please say yes lol. {edited for privacy}.

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26

My doctor gave me Nucynta 50 mg for severe nerve pain. I took one and felt nothing, so I took another with no relief still... Then I took another and oh boy, my heart felt like it was going to beat out of my chest. What's inside of them? No other pain med that I've taken had that kind of effect. By the way, I felt no pain relief either.

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I'm taking 150mg Nucynta at night and 50mg during the day. Now I suffer from severe memory loss and obsessive compulsion. I'm taking Nucynta for severe CRPS and RAD post shoulder surgery. Anyone else?

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29

Nucynta Er makes me very tired in the afternoon, but reduces pain 60+%. Anyone else have a similar tiredness reaction?

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Nucynta gives me 100% relief of my sciatic nerve pain. Unfortunately, the minute I take it, I have to lay down or I get nauseous. I call it the LSD/Reiki drug because my mind becomes very active and I have incredibly vivid thoughts. It also feels like I am getting Reiki because I can feel the drug going to work where I have nerve pain. It does not help me with any other type of pain. I am prescribed 4 doses a day. I take about 2 doses a month. I use xanax daily for muscle spasms. I feel no side effects the day after, just relief from having the pain diminished.

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8

I have been taking it for 2 years they worked at first but they get Mr really high and I hate it and it doesn't work anymore .

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I'm on it now.I just came off from Methadone 10mg & It's not as strong, nor is it as strong as oxytocin or oxycodone. I'm on the 50mg Nucynta. The benefits to me are better as far as less side effects. You still get the warm feeling but no itchyness. Although be very careful of the serotonin levels. Stop taking fluoxotine if you're on it. It will give you serotonin syndrome.

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I've been using this medication for over a year now with significant success. If your insurance will atleast partially cover it, its well worth trying for chronic pain, ESPECIALLY nerve related CP. As some anti depressants are now being used for nerve related CP, Nucynta gets roughly 40 percent of its action from Norephedrine reuptake inhibition. Its primary mechanism is still via the Opioid Mu receptors (the same ones hydrocodone and others affect) but the difference of adding NRI activity is very noticeable in terms of pain relief. It also makes the medication less "drowsy". Its considered less addictive than Oxycodone but still has a potential for abuse....with this being said this medication builds tolerance considerably slower than traditional narcotics, so the same dose you take now should work nearly as well a few months from now.

As for side effects, these mostly occur if you accidentally take a second dose miss timed (too close together) as the effects seem to ween down a bit slower than traditional narcotics due to its NRI activity. However, they are substantial in higher doses vs lower ones on almost a curve. For example, 75 mgs vs 150 (taken only at this dose for break through) the effects seem X4 instead of X2. At the 75 mg dose, I generally have few side effects and my cognitive abilities seem to be better than that of when I was prescribed traditional narcotics for my CP. One side effect is increased well being. However, occasionally this can mean a bit too much energy and over talkativeness. At 150 mg dose, I'll experience a total relief of pain but in exchange, ill experience potent anxiety and sometimes it'll feel like my chest/neck is tightening which makes it harder to breath. I believe this might just be a side effect of the increased anxiety. At the 150mg dose, moderately-mild "quick" hallucinations generally occur, such as hearing faint music that doesn't exist, corner of eye, distant items appear "differently" for a split second, not to mention surreal closed eye daydreaming that's very lucid. Again at the 50-75mg range, these two side effects shouldn't occur often and should be minimal if they do. Ultimately the pros far outweight the cons. Just watch your dosing, use only what you need, and you shouldn't have too many side effects.

Ohhhh one last thing. This medication WILL dehydrate you if you do not drink water adequate while under the medication.

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I haven't used it, but I can provide you with some basic information on it.

Nucynta contains the active ingredient Tapentadol, which is a centrally acting analgesic. It is related to opiates, so the side effects it can cause are very similar and may include: nausea, dizziness, constipation and dry mouth.

Learn more:

https:/­/­rxchat.com/­wiki/­Tapentadol/­

Is there any one that has used this and can provide more information?

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