Multiple Sclerosis And Oxycodone
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I was diagnosed with multiple sclerosis in 2008. Over the years my nerve pain has gotten a lot worse. The pain has gotten so bad that it's ruining my life. I cant walk due to my legs not working correctly and experiencing a loss of all balance. I have pain everywhere but it's the worst in my feet. My Dr. has me on 10 mg oxycodone for about 5 years now. I was on percocet prior but I worried about my liver with all the acetaminophen. My problem is I'm not sure if I have built a tolerance or if I should be taking more at a time but it's not doing much for me. My pain never goes away. The pills slightly take the edge off for about an hour. That's it! I have tried 3 different types and strengths of pain patches and they didn't do anything. I tried morphine with the same results. I even went to a pain specialist who took me off oxycodone and put me on methadone and gabapentin. I had to stop those after one dose because I was in so much pain and wondering why, so I called that dr. and he said it takes a couple weeks to work. There's no way I can miss any pain med dosage. Let alone a couple weeks. Can anyone steer me in a direction to help me not be in misery all day? Thanks for your time.

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Re: Don (# 34)

Hi Don. I do agree with your input,regarding most Pain-killers and that ones body,however does develop resistans and addiction. In my case i have been on Stilpain for 6 years now. Yet,regardless of the high addiction capebility of this particular pain killer..only after SIX years,it now started to loose it's efectiveness. My only and last resort,in South Africa,is Morphine or PREDNISONE. The huge problem with Prednisone,is that it has severe side effects and can turn fatal,if used for more than 6 months continiously.It's very efective for pain,espesially MS patients.Was sugested that i stick to Stilpain for as long as i can,even if i drastically increase my daily dosage.(including switching to Morphine also)

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Re: Nosie Nellie (# 40)

Several decades ago they did a spinal tap on me. Which involves placing a needle in the dural sac(contains the spinal cord) to remove fluid for testing. They did this to test me to see if I had MS.
I don't know how they do it these days...

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Re: Hennie (# 39)

I'm not sure if I have MS I have many of the symptoms. I have a an appointment to see my neurologist on Wednesday to discuss the possibility. I'm more than a little concerned, but I want answers. I'm not even sure I should be posting on this page, but reading all your information you are so knowledgeable about the illness. I'm familiar with pain as I have numerous illnesses for which I've been seeing pm drs for several years. It's the new symptoms that I have been having for the last few months that have me concerned. I'm curious as to how some of you we finally diagnosed with MS. I'm? sure you all would rather I not be posting, but I'm trying to find someone MS that could maybe guide me.

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Re: Mark (# 38)

Thank you for your respons Mark.From the bottom of my heart! God Bless.

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Re: Hennie (# 37)

God bless you Hennie and your personal journey through this horrible disease called Multiple Sclerosis. I hope that your doctors aren't scared to prescribe pain medications in sufficient dosages to help you tolerate this insane disease... I had a close relative that had MS and I'll never forget the courageous battle they fought for many years to live a life in a body that fought against them hour by hour. Reading your post brings tears to my eyes remembering them and their struggle. A lot of us here on Medschat that have bad injuries sometimes forget how lucky we actually are to not have a horrible disease like Multiple Sclerosis...

Hope you have the best Thanksgiving you possibly can Hennie, bless you.

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Hi all. Regarding my MS... For pain i can only stick to Stilpain and Lioresal 25mg. In South Africa those 2 kinds of meds remain 'last option' for me. Except Morphine for pain relief. Last 2 months my pain in neck and spine suddenly got worse, to a state that nothing even helps CLOSELY! The pain goes from the neck to my eyes. My vision decreased to about 50% and my left eyeball has moved to the side of my eye-socket, causing double vision. This pains is 100 times worse than the worst migraine, mainly right into the skull, where all spine muscles meet the lower brain lob. Also bad pain and difficulty to walk, from my hip to foot on my right leg. However, my Neurologist suggested that i should try walking every day, to prolong the muscles from giving in..OR dayle fisio. The walking every day really helps with the muscle pain and after a while, i walk 'normal'. What also is on the increase, is my short-term memory and speech. My BP could not get controlled for 5 years now. It remains around 170/90. Now it suddenly started dropping continuously to as low as 90/40. Dr suggested that i must not alter my BP meds yet! But after all is said and done, my MAIN Dr remains GOD and i'm still managing every day as best i can. Regards and never lose HOPE!!

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Re: ISE (# 35)

I was on opiate painkillers for 25 years. I'm still alive, no overdose, started at 30mg per 24 hours.

In 2016 with the opiate scare all doctors pulled the plug. All had to go to detox centers.

I did a home detox and had 40 days of medicine to withdraw from a 260mg amount per day, which is the amount they give you for 2 crushed hips.

I did it... I never thought after 25 years of daily morphine/oxycodone I could do it. It took 18 months for my body to readjust from gastro problems, weight loss of 40lbs, to gaining 50 lbs. I'm glad I detoxed.

Don't be so quick to blame doctors. It's the entire medical system.

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Re: Don (# 34)

Ok, don't understand why ppl vote down when they do not like the response/answer OR the TRUTH given to them. Don thanks for taking the time and answering that. Think people now just don't understand today, 2017 is a time where Docs are making it harder to obtain opioids/opiates/narcotics/painkillers EVEN IF you have a LEGIT REASON FOR IT! Been on them for 12 yrs, with pain management my Dr is now out of network and I can not get a bridge script until seen by a new DR. I did get a continuation of care by my insurance company for this reason but denied by the Doc, wtf!!

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Hi,

With any ongoing use of any opiate pain reliever you develop a tolerance to it. If its oxycodone, hydrocodone, or morphine your body builds a tolerance. Thats what addiction is all about. In old time thinking 70s, 80s, 90s early 2000 all drs just prescribed more pills to cope with pain. Adding to the addiction of opiate painkillers. When many people start off they may have been on 30mg total per day...then to be prescribed 60mg per day 6 or 12 months later to end up in triple numbers 100 to 200mg per day plus after 2 years.

You're not in the eyes of doctors an addict because you're not seeking out law-breaking things to obtain painkillers. But your body is certainly chemically addicted to pain medicine after your first 30 mg per day prescribed habit. It's getting detoxed and reprograming pain receptors in brain to be able to use the least amount of painkiller to be comfortable. Remember painkillers were not designed to kill all pain but to make pain manageable. There are many non opiate medicines that can be prescribed that make living with pain more comfortable. Prednisone a great anti-inflammatory medicine. Along with many other nonaddictive medicines.

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Hello everyone,

I tried to find a spot to just post what I wanted to say but was only able to respond to something for it to post.

I was diagnosed with MS about 4 yrs ago. I was told by my neurologist that according to some of the lesions I have I had this illness for many yrs. I can actually remember around the time when I knew something was wrong. The very first time I went to a neurologist was about 25 yrs ago. I remember losing my vision. The neurologist gave me blood work and found I had thyroid disease. I can remeber the neurologist taking the blood test again. He thought the reading I had may have wrong. He stated that normally when people have critically high/low results like I had were normally in a coma and at the time I was working 70hrs and more a week. I was very tired but blamed working 7 days a week with many hrs as the cause. My thyroid results were the same as the first test. After he gave me synthesis he sent me in my way.

I struggled everyday with the nerve pain every single day for as long as I was able to. Approx 6yrs, and until I just couldn't do it anymore. I was never in any pain medication before and never believed in it. I always thought people just wanted to get high from taking that magical pill so I never took a pain pill. About three yrs ago I was in so much pain I had to walk with a walker, couldn't drive myself anywhere, couldn't lay down, sleep etc etc. The pain was so bad it hurt to even eat. The Dr tried putting me on different meds. Dilaudid or whatever it's called, Percocet, Morphine etc etc. None of it worked without being a zombie.

Then the Dr put me on Oxycodone 30mg. I'll never forget how I felt within 15 minutes after taking that pill. I still cannot believe how much of all of my pain was relieved. For the first time in a month I was able to get in and out of my bathtub. It was the best bath I ever had in my life! I was even able to literally wipe my own ass. Little by little my life started to come back. I was even able to volunteer my time at an animal shelter and was thinking about going back to work. The volunteering was allowing me to see what I was capable of doing and how much I'd be able to do. I was never able to stay consistent. Some days I had were really bad. To the point I could not get out of bed or move for the entire day. I can remember the feeling of dread I had thinking that I couldn't take these pills because of how sick I felt and how I would throw up.

The Dr gave me a script to ease the sick feeling and it worked. It was no longer an issue. I was initially put on the 30mg 4 times a day but never really needed it 4 times a day. The Dr started to lower my dose which I was fine with. Eventually I went to the 30mg a day. Last month the Dr took me off the 30 mg and put me on 15 mg. I noticed immediately the difference. There was a difference taking 2 x 15. It makes me very groggy and I felt like I didn't want to do anything. I decided to just take the one pill in the am to see if it worked. Unfortunately the 15mg doesn't feel as if it helps my pain. I'm in more pain this month than I've been in for yrs.

My Dr wants to completely take me off of this med. I understand the reasons as to why. Apparently the medication causes people to die. Most of all of my old pain came back. My migraines was the first thing that came back and everyday. My dizziness came back more, the nerve pain in my hands and feet is horrible. I used to have a system when I woke up to start my day. I would get out of the house and do things I needed to do. This last month my quality of suffered a great deal. I don't know why this 30 mg works so well for me. I'm actually beginning to think that it jump started my body to access my natural opiates. Even though 2 x 30 worked perfectly i am able to tolerate one 30mg a day. I really think way more studies need to be done for the 30 mg.

I never had an addictive personality or was able to relate to being an addict. I still don't understand why people abuse medication or take it when it's not needed. I'm certain I'm not the only person this medication truly works for and improves a persons quality of life. It's saddens me to see the medical professionals not seeing the benefit of how much this medication can actually improve a persons quality of life and help. Not all people on this med abuses it. These were the medications I was on when I started this med and the meds I was able to get off of being on this med: Ativan, Lexapro, and Ambien. It helped me not only physically but mentally and I was finally able to sleep well without a sleeping pill and never felt the need or desire to off myself.

I truly fear going back into the hell I used to live in without the Oxycodone 30. I even told the Dr to give me random drug tests and check blood work all the time and count my pills randomly if needed. It is so sad that a pill that can help so much will never be recognized as being beneficial. I wish people wouldn't abuse this med and wish Drs would do more to study the benefits it will actually have in a persons life. I'd also want to know if it's possible for the human body to naturally be able to access their beneficial hormones from taking oxycodone 30? This pill seems very different compared to the 15 mg. Good luck everyone and hope all find relief.

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Hi. I was diagnosed with MS in 2012. I was prescribed- Lioresal 25mg at night and Stilpain 2- tds mainly. It workded very well for pain. Until 2016.Because my MS progresed to 'Progresive' MS. My Neorologist now increased my Lioresal to twice a day/Stilpain dosage remained the same,but added Prednisone 2 tablets twise per day,IF and when the pain gets worse some days. It works 200% for me and i'm pain free. Stay strong and God Bless.

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If you do go with lyrica.beware of weight gain legs and feet swelling and thoughts of ending your life plus stomach swelling i looked like i was 9 months pg.i have been trying to get get this drug off the market. It is very dangerous.some can take it but alot of others can't.it did help with the burning and stinging in feet.the bury vision.for me the side effects on top of ms.i just wanted to die.it has been over a yr. Since i took this drug i am almost able to walk again.but the pain is always there.just be aware of side effects.I hope you can find relief.i haven't so far.

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I have written answers to this for a solution for you, but I have been in touch with a medical professional for you, and I go by my own experience as I said I was injured with constant chronic pain and do much testing on myself. I was told to reccomend you try pregablin.... not the less developed gabapentin which has to metabolise into pregablin in your body and this is inefficient. Pregablin (Lyrica) works for many. I suggest you try it as it can be indicated for your condition.

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Try that curmin it work for me you have to take 6 capsules when you take it but keepp it up until it gets better please try it

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Be careful with the ginger root , although great for pain and inflamation if you take high blood pressure medication make sure you check with your doctor first.

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Get yourseld in direct sunlight for 15 minutes every single day without fail. Spring is here than Summer so make sure you do this. Under "NO" circumstances whatsoever should you allow yourself to misout on the direct sun every single day and I hope you get my insistence and follow thru with it as it will otherwise be down right unfortunate for you if you choose not to follow through with this very simple necessity. Also as soon as you read this, make appointment with your doctor for vitamin B-12 shots (quick injection in your arm and probably every two (2) weeks but your doctor will decide.

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What a helpful person you are, I also seen this and cannot for the life of me remember, it's these damned meds ;-)

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I've got nothing but empathy for you
It's become so hard for Doctors to help people like us with our pain, do to so many others becoming addicted and ,abusing these meds,causing a stigma for people with our chronic pain issues
I don't suffer pain from same issue as you
I was involved in a very serious motorcycle accident&have had so many surgeries,procedures(as the medical. Professionals seem to prefer to calling them)

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I was on 3200mg of Gabapetin and it just made me more miserable! I
Topiramate (Topamax ) 200mgs twice a day + I found out I have Vitamin D &B12 deficiencies
contributes or mImics additional nerve pain.

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I looked into some research articles, and am not going to use scientific jargon for you, I would need to know some answers first, like the dosing levels of the opiate/opioids. I seems clear you were not given a large enough dose. There may be reasons for this, reduced liver function is usually a reason. However you are here for help, and help is what I will attempt to give you. For first line pain I suggest dihydrocodeine tartrate, it comes in slow release (60, 90 and 120 mg) These may be useful later. But first you may try instant release 30 mg., you must ask if there is any reasons you cannot take it, I do not want to be responsible for inducing damage. Try a 30mg, if no good after 20 minutes try another, basically titrate (up the dose) until you are feeling relief.... it has to be Dihydrocodeine, not simple codeine which has a ceiling effect which is when your liver cannot metabolize the codeine into morphine in your body quick enough thereby giving not enough therapeutic effects.

Next you will try a benzodiazepine (diazepam, Flurazepam etc) now opiates and benzodiazepines have a synergistic effect and if you take too much of both you are dead. You must start small, and work up, benzodiazepines themselves do not cause overdoses, it's mixing with opiates that causes overdose. So I am asking you to be careful. Then as I suggested before.... CBD...... this is acting like a miracle cure on me. Years of research into the amazing (yes I say amazing) benefits of cannabis as DuPont, the maker of nylon, seen hemp as a threat to profits, and demonised hemp products. We could have had a cure for all cancer today. But I very much suggest CBD..... and do we care if there is a little THC in (the psychoactive part of cannabis) it's your body, your pain. Incidentally dihydrocodeine is the closest chemical substance to diamorpine. I hope this helps. And I wish for your situation to speedily improve, just be careful and have someone who can give resuscitation when mixing benzodiazepines and dihydrocodeine..... please..... and use sense. Start small and work up. If my feelings are correct, a day should give you an idea of the doses required. Best of luck.

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