Mounjaro Forum (Page 2)

First month started with 5 mg. Just started the next month with 7.5 mg. Lost 14 pounds. Used to take 3 meds total. Now just once/week Mounjaro injection and Jardiance 25 mg daily. Morning sugars 120.

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My experience, crossed in to diabetic territory in 2019 but doctor missed it on a blood test. Uncontrolled till diagnosed in spring 2021 with a1c at 7.6 and fasting glucose I think 147. Metformin knocked a1c down to 6.5 but side effects were really bad for me. Juanuvia had really bad side effects. Jardiance 25mg daily had my a1c at 6.7 with know side effects and decent morning glucose levels I think maybe in the 105 to 120 range but not sure. Problem was after meal glucose spikes up to the upper 200s (260 to 280s at times).

Added Mounjaro to Jardiance up to 5mg dose. Result was a1c at 5.3, technically below even the pre-diabetes level. Fasting glucose on actual labcorp tests in the mid 70s. They warn about low blood sugar risk at that level. But not eating for 15+ hours had no problem where as my pre-medicated diabetes it sometimes happened in the morning.

Other benefits, lost 35 lbs that I gained from Adderall. Lowest triglycerides in my life. Bad cholesterol probably lowest since high school. Good cholesterol increased slightly into the bottom of normal range (genetics in my family often have it low). Combination of Metformin and Adderall gave me heart palpitations and high blood pressure. Tried several blood pressure meds all with bad to terrible side effects. 2 months on Mounjaro 2.5mg, blood pressure was 107/75 at doctors office while off BP meds for a while and on 100mg of Adderall (I know it was a high dose, Adderall can help or hinder psychoactive meds and blocked my Adderall from working which is a whole 'nother post.).

After meals my glucose level stayed under 140, 2 hours later. Even tested it with a large bowl of ravioli, can of regular Pepsi, and sugary desert. Stayed under 140.

My results may be better than others as not being diabetic as long as many others.

My father's a1c was over 8 even on metformin 3 times a day and trying adjunct diabetes medications. Glucose spikes seen over 300 after meals and he goes for walks daily and doesn't watch what he eats as much as he should, but does watch what he eats. Was put on Ozempic as insurance wouldn't cover Mounjaro. With Metformin and still a relatively low dose of Ozempic, a1c dropped below 7. Morning glucose was good but I forget numbers. After meal spikes peaked over 200 but in 2 hours was below 140 without going for a walk yet. He actually gets best results after eating some sugary food as it prompts insulin release and Ozempic tells the body to listen to it which attenuates the insulin resistance and uses glucose resulting in a lower morning glucose levels than not eating something sugary in the evening.

Difference between Ozempic is that Ozempic is a GLP-1 analog molecule and Mounjaro has a GLP-1 and GIP analogs. The GIP analog is more effective at increasing cAMP with tells the body to use glucose when insulin tells it to. But the GLP-1 analog is better at not causing down-regulation of something I can't recall off the top of my head. Overall, Mounjaro has been found to be a little better than Ozempic but both work well. They are of course working on other related drugs to maximize profits especially when patents run out and generics are allowed.

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I’ve been on Mounjaro since end of March 2025. Combined with a low carb diet I am down from 146KG to 117.5. BMI from 42 to 34. Copilot tells me that this is well above the normal for BMI and Weight. I’m currently on 10mg per week dose.

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Re: MD (# 12)

In the U.K. it costs about £500 for 12 weeks. Plus a consultants fee if you are using one (£250 per month).

I easily save that in deliveroo/Just eat bills so no nett difference in spending.

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