Midrin Where Can I Get It

I have been taking Midrin for the past 10 years for migraines because I don't get any side effects from it and it works really well. Now all of a sudden the pharmacies in my area (3 of them) are saying that they can't get any or it is on backorders for the past 3 months. Do they still make it? I tried a different medication and it makes me really dissy so I really need to know how to get the Midrin. How can I get a presecription filled and where even in the mail would be ok.

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IVE BEEN TAKEN MIDRIN FOR 8YRS ALSO NOW THEY TELL ME LAST MONTH NO MORE NOT AVALIBLE BULL, CAN ANYONE HELP ME ON THIS OR A GENERIC IVE BEEN SUFFERING FROM MIGRANES FOR 35 YRS MIDRIN WORKS IF YOU KNOW OF SOMETHING ELSE OR BETTER LET ME KNOW THXS

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I am sorry to have to inform you of this, but that is correct, Midrin and other products or generics that contain these same ingredients are no longer available in the U.S.

The specific ingredients were Acetaminophen, Isometheptene and Dichloralphenazone.

The reason it has been discontinued, by all manufacturers is that this medication was actually never approved by the FDA. It is an old drug, that was basically grandfathered in, when their new policies went into effect, however, for it to continue being marketed, the companies that manufacture it must now do studies on its safety and efficacy. The FDA has started cracking down on these 'grandfathered' medications and many companies have chosen to stop making them available on the market. Their reasoning for this is unknown, but it may be related to sales of certain medications. For instance if they aren't big sellers, it may not be worth their expense to undergo the testing and approval process.


The only suggestion I can make is to talk to your doctors and discuss your other treatment options.

You can learn more about them and the FDA approved treatments here:

https:/­/­rxchat.com/­wiki/­Migraine/­

Are there any questions or comments?

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Can you let me know if you find anything that works as good as Midrin. I tried Fiuroset and it made me really loopy and dizzy. Nothing has ever worked for my migraines and I have had them since I was a kid. I called the doctor to ask for Amidrine and he said none of the meds with the same ingredients in it are available any longer. So, the latest news on this website must be correct because of the lack for FDA approval. That really stinks because I never got any side effects from it.

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You said it wasn't sold in the US any longer, but is it sold in Canada? If so, how would I get a perscription filled there. Thanks for the info.

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I am also looking for the generic version of Midrin. It also works better than anything else for me. I see that it can be ordered at Pharmnet RX on their web site. I have just placed the order and must have the script sent to them, so cannot say with 100%accuracy that they have it available. check their web site out

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I just want to let you know that i am a compounding pharmacist and I can compound midrin for patients in california with a prescription. please contact me for more information.

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06/23/11- You can still get Midrin at compounding pharmacies! I just got some today. They simply order the three ingrediants that are in midrin, compound them, put them in the capsule. My price was $55 for 60 caps or $45. for 30. Just google compounding pharmacies in your area.

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sherri where did you get them. I have checked with some compounding pharmacies and have been given prices that are much higher. thanks, penny

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Let me update this. When I said I "got some today" I meant I called the compounding pharmacy and was told no problem - here's the price. When I went to pick it up they said "We cant make Midrin". The second pharmacist at this pharmacy told me to tell my doc to not write "Midrin" on the prescription, but to make the prescription for Acetaminophen, Isomethaptene and Chloralhydrate. These are the ingrediants in Midrin. (Something about copy rights for the name Midrin.) The pharmacist said when it's written that way they can make it. I fogot to ask what the price will be but I'll let you know the outcome and the price.
So the original pharmacist I spoke to was incorrect in what he told me. I'm going back to my doc and getting a new prescription with those specific ingrediants on it and see if that will work! My pharmacy is Springhill Pharmacy in Wheat Ridge CO. 8550 W. 38th Ave. I'll keep you all updated.

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Thank you so much for this information. I will ask my doctor at my next appt. and let everyone know what the outcome is. I have a local compounding pharmacy that I will try once I get what I need fromt the doctor.

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If you live in Virginia, Stuarts Draft Family Pharmacy, (near Charlottesville) can compound this medication for you. They cannot ship out of state.

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Yes! When i had the doctor do the prescription for the individual medication that make Midrin the compounding pharmacy did make up for me! My doc even spoke to the pharmacist. Acetaminophen, Isomethaptene and chloralhydrate are the ingrediants. I have it in my hand now! You can get "Midrin"!

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This is great news. I suffer from debilitating menstrual migraines with pre-ceeding aura, and Midrin is the only thing that has worked for me. It is a lifesaver and allows me to go about my day normally instead of ending up in the emergency room. I will speak to my doctor about having it compounded. It would be nice to not have to ration what's left of my Midrin once knowing it could be compounded and available to me in the future. Such a shame they stopped making it. It's an inexpensive drug and lets people live productively without wasting so much money and resources in emergency rooms.

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Lee Davis Compounding Pharmacy in Mechanicsville, VA will compound Midrin for you. The drug consisted of ISOMETHEPTENE MUCATE, DICHLORALPHENAZONE, AND ACETAMINOPHEN and we have all three components available. Have your physician contact us at the numbers below or feel free to call us if you have any questions.

Visit our website at leedavispharmacy.com
Lee Davis Compounding Pharmacy
7023 Lee Park Road #A
Mechanicsville, VA 23111-3608
Phone: (804) 730-9200
Toll-Free: (877) 786-3071
Fax: (804) 730-3871

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I am posting a follow-up because I have been taking chelated magnesium as a supplement once a day and have not had any aura or migraines for over a month now. I had recently read that this helps with menstrual migraines, which I suffered from on a regular basis for several years. I take Solgar brand which is available at Whole Foods. While I'm not completely sure this is the exact reason I have been migraine free, it's worth sharing if it will help someone. I do have a "stockpile" of Epidrin that I have thankfully not had to dip into. I have experienced tightness between the shoulders, and the "beginnings" of a headache a few times, but it quickly subsided. Do an internet search on magnesium for migraine and you will find more information. Worth a try since Midrin and generics are not available.

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Thanks for sharing this. I suffer from migraines like this too. I am going to go to Whole Foods tomorrow and try this to see if it helps me.

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WE AT LEE DAVIS COMPOUNDING PHARMACY,ARE MAKING A GENERIC VERSION OF MIDRIN. IT HAS THE SAME ACTIVE INGREDIENTS. LEEDAVISPHARMACY.COM OR CALL 877-786-3071 WE HAVE FREE SHIPPING!

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Can you recommend a doctor who will write such a prescription--for Midrin, or for its 3 components, or for the 3 component (with Chloralhydrate as a substitute for Dichloralpherazone)? Anyone in Minnesota? I have suffered from migraines for nearly 40 years and I have tried everything. Midrin is the only med that works for me. My family doctor tells me that he can no longer legally write a prescription for Midrin, so he refuses to even talk about options. I have the sense that he thinks I am trying to talk him into doing something illegal, which seems to make him angry. Thanks.

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Hi, I too took Midrin for about 20 years. They have come out with a new medication called PRODRIN, it replaces the sedative with caffienne. It is available by perscription and it works just as well. I had to tell my nuerologist about it. I found out from my pharmacist. I am grateful they didn't just throw out the whole idea. PASS THE WORD. There is a replacement!

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i found on another site in response to midrin being discontinued that a compunding company in delaware was still making midrin at only $1 a pill - its called safeway compounding company (you can google it) and they are OUTSTANDING!! you just need a prescription from your doctor for as many ppills as you would like and within a week they send it out to you by ups with a shipping cost of $10 - but these prices are amazing compared to what i was paying at the pharmacy hen i could get them locally - i HIGHLY recommend this company and suggest that you spread the word to any and all migraine sufferers everywhere ! their customer service is superb as well - good luck!

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Re: JJ (# 123)

Red die causes nausea? Heck, migraines cause nausea.

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Re: Catherine (# 128)

This is absolutely true. The mfg was sent a final “cease and desist” letter last month (google Midrin shortage and it’s the very first result)

So all that’s left is what’s out there. That’s the truth. Grab it while you can

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Re: Aapman (# 121)

I was able to buy the last six in my town, but the pharmacists said there is no way for them to get any more. My suggestion would be to try shopping around at small-town pharmacies that may still have a few... then horde them! They are more precious than gold to most of us. Best of luck and I hope you find something that works for you.

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Re: kaati (# 126)

That's really interesting as I just got a local compounding pharmacy to make some for me. They used something different than the Dichloralphenazone but the Isometh is still in it. Not saying the name of the pharmacy. But worth a try to call some local compounding pharmacies local to you to see if they will compound it for you. If you find any, don't share the name online.

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Re: JJ (# 123)

According to the FDA notice, any drug containing Isometheptene Mucate would need to go through the new drug application process. Since a drug company would have to spend millions and 5 - 10 years to even try to get approval, it's never going to happen. Really sucks when Midrin is the only thing that's worked without major side effects over the last 20 years!

[1] FDA Notification Regarding Isometheptene-Containing Drug Products

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I've been having trouble getting the Isometh/Dich/Apap Midrin equivalent as well. CVS couldn't get it so I switched to Express Scripts, and as of today they no longer carry it either.

Some googling led me to a letter the FDA sent out in Oct 2017 that ordered any company manufacturing or distributing Isometheptene Mucate to stop. Therefore the Midrin equivalent is now illegal in the US. Every other option I've tried has had terrible side effects.

[1] fda.gov/downloads/Drugs/EnforcementActivitiesbyFDA/UCM610712.pdf

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Still cannot get it anywhere including Canada. I just had my Dr call in a compound prescription to our local compounding pharmacy. They use something different than the Dichloralphenazone (which they cannot buy but the replacement does the same thing according to the pharmacist). I have had them compound it for me before when the FDA first caused a cancellation and it worked the same for me.

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Re: Kat (# 122)

Midrin is my go to and I cannot get it filled anywhere. CVS told me they will no longer carry it. When I spoke with my doctor she said since it was not FDA approved and the FDA is cracking down on medications that Midrin will no longer be manufactured. I have no idea what to do. They listed several reasons for removing it from market like it contains red dye and causes nausea. All of which I think it ridiculous. I hope they get FDA approval and come back to market with it.

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I just checked at CVS and they said it was on backorder until July., My son has intractable migraine. I used to have migraines, too, but at that time I only paid $20 for 100 capsules. I don't understand how it got so out of control.

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Re: Ann (# 120)

I've been told there is none to be had in the US. Where can anyone still get Midrin or equivalent?

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