Metronidazole Lasting Side Effects (Page 69)

I have been taking this medication for 7 days and off of it since a week and still have severe side effects, abdominal cramps, severe headaches, dizziness, unsteadiness... How long is it expected to last? It was prescribed with Ciprofloxacin to me and I take Entrophen on a regular basis...

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Betty (# 1358) --

Metronidazole and Cipro can cause mitochondrial dysfunction and possible damage--mitochondria are the energy source of your cells, which explains your lack of energy and other issues. Metronidazole causes this by indirectly taxing/harming mitochondria by starving it of the vital nutrient, vitamin B1 that mitochondria require to function. Cipro, unfortunately, can directly damage the mitochondria, so there's no one vitamin that can effectively treat it. I would suggest, if you are dealing with Cipro-related problems, to look up floxie hope in the search engine and read recovery stories from other victims and see what they suggest (and what to avoid). Do some research into functional doctors who are aware of fluoroquinolone toxicity (aka, Cipro-toxicity). Good luck to you.

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Re: Erin (# 1359)

thank you Erin, I'll do a bit of research... my nutritionist recommend a lot of stuff but that ends up being tooooo many pills and my system rebels at about the 3 week mark and I end up "forgetting" to take them...

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Erin (# 1357) --

Thanks for the info Erin. Can you please link the document(s) from where you were quoting?

Best
Dennis

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Re: Galina (# 1355)

Thanks for the warm letter Galina. Sadly my condition continues to worsen. Everything changed overnight in late June of 2017. These multiple nightmarish symptoms began within 24 hours of ingesting this poison that they wrongly call a "safe" antibiotic. Like a Hot Potato, doctors continue to run away from me, yet some have admitted that there is evidence of cerebral damage and disease exacerbation while others are theorizing the Metronidazole may have triggered a severe case of SLE, or Systemic Lupus Erythematosus which is an severe Autoimmune response on top of everything else. Whatever the case, FLAGYL and the doctors that gave it to me have literally destroyed what's left of my life. Merry Christmas Galina, I will pray for you!

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Dennis (# 1361) --

Here's my blog and it has links to my references:

metrogirlblog.wordpress.com/treatment/

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I started using metronidazole for stomach flu, but after taking it for 3 days I can't stand the side effects like abdominal pain, terrible headache, nausea, dizziness, and so on. I had to stop it and the effects are lasting. This is a toxic drug...

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Re: Dennis (# 1364)

Hi Dennis, I can definitely say that this drug is an evil and don’t understand how doctors easily prescribe this poison and say that it is a SAFE drug! After what happened to me, I’ve learned a lot about the doctors and big pharma ‘genuine’ intentions and I am not planning to take any of the prescriptions. I would rather die than take the poison they call SAFE to take. Dennis, when I saw my Naturopatic doctor, he mentioned one of his patient that developed Lupus after taking Cipro and he treated her with glutathione IV for some time. This doctor is very familiar with Cipro toxicity but not with metronidazole. So basically he has no knowledge about metronidazole / FLAGYL toxicity. But he recommended me to eat as clean as possible, reduce the stress level, and time, time, time. So I hope that as time passes we all get better. I pray to God that he helps all of us who is still suffering. Have a good night and hopefully you start getting better soon!!!!

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Re: Erin (# 1365)

Thank you Erin! Have you seen this fairly new document? Licensed manufacturers of Flagyl® all over the globe have now added this InfoPage with prescription Flagyl. Notice the clear warnings concerning neurotoxicity. https:/­/­jmp.sh/­Yb5QsVi You may wish to add this to your blog. The manufacturer has yet to respond as to the reason these new warning were added. It's a long detailed story.

Before I was severely harmed by this antibiotic, I was the director of the EDNC here in Washington DC, a patient advocate collaborative representing thousands of harmed individuals all over the world after they suffered severe outcomes following ESI therapy. I was instrumental in pushing the FDA to make significant label changes to Pfizer's DepoMedrol, a particulate steroid being used off-label for Epidural Steroid Injection therapies with low efficacy and high safety risks. In 2014 we made considerable progress after several advisory panel hearings decided to grant many of our proposed changes but refusing to contraindicate the drug for epidural administration.

Thanks for your blog.
Merry Christmas
Dennis

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Re: Seth (# 1366)

You’re doing the right thing Seth, the sooner the better are there is no known antidote. Keep us appraised of your recovery!

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Re: Dennis (# 1368)

No, I haven't seen that one, just the FDA label and the FDA adverse drug report that I requested from 2015 (plus medical literature information). There are warnings on the FDA label about the drug's neurotoxicity, including cerebellar lesions and nerve damage, but since it's created by Pfizer, they gloss over the impact and act like the lesions and toxicity are no big deal.

Last spring, I contacted Dr. Charles Bennett, one of the leading patient advocates for ADR, but unfortunately--while he seemed enthusiastic about leading the charge about metronidazole when I first talked to him, even giving him his personal email and cell phone--he's been ghosting me ever since. I have no idea why.

If you want to get involved in helping with getting better recognition of the dangers of metronidazole, we have a support group I started in 2016 (the link is on my blog) that's now up to almost 400 victims. The group is only for metronidazole toxicity.

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Re: Seth (# 1366)

Seth, I'd suggest getting some thiamine (aka vitamin B1) and magnesium (I like magnesium threonate the best, as it crosses the blood brain barrier). Metronidazole destroys thiamine; you need magnesium to absorb thiamine, so that's why you need both nutrients. Start slow, build up. You can take high doses of thiamine as it's water soluble. See my blog, linked a few posts below, for more details. I'm not a doctor, so you will need to make the final decision is you agree with the treatment or not, but I've researched this drug for over 3 years and the leading researcher of thiamine deficiency disease, Dr. Derrick Lonsdale, agrees with my findings about metronidazole.

But you will need to decide what's best for you.

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Re: Erin (# 1371)

I've some new info that I thought I'd share. And no, I don't have any resolution or plan yet.

I took this medication in Sept 2016 for h. Pylori bacteria. I was sick before I finished the dose, doctor convinced me to just finish the dose if I could stand it. Afterward I was even sicker. At some point my eye doctor who was also a patient of my regular doctor saw me and told our mutual doctor to get me in and see what was going on. I was diagnosed with ataxia and polyneuropathy. After months of PT and yoga and tai chi I was able to stand up and walk well enough to walk in the Women's March in DC in Jan 2017. And I got better until March 13, 2018 when I went to the Dr for a suspected UTI and was given cipro before BEFORE waiting to see what bacteria was involved. I made the mistake of taking it. About 24 hrs after taking the first pill I got really sick with similar symptoms PLUS extreme exhaustion. 10 months later I'm struggling to function. About 2 months ago I was given a referral to CUHealth's neurology dept. 4 weeks ago I had that appt and bloodwork was taken and I was referred to an ENT for tests (so far the ENT hasn't called to schedule and appt with me) and then the blood work started coming back. All were negative except Calcium Channel Binding Antibodies....which my research shows connected to some kind of cancer. I've known about small calcium deposits in one breast which have been monitored for 4 yrs now with no changes. The neurologist says it is probably related to that (called carcinoma in situ) and that my body is making antibodies against it. I asked if removing the calcium deposits wouldn't be a good idea and he said no, we'll just treat the symptoms!

I'm seeing the oncologist today and talking with her about all this to see what she says. I'm excessively upset about all this. So my GP says I should see a counselor to help me cope. COPE? what the hell does she think is going on. that I'm just worried and talking will help? How do you cope with the fact that you likely have cancer somewhere and they don't have a clue where or what kind and the neurologist thinks you should just treat the symptoms?

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Re: BAH (# 1372)

Wow, I'm really sorry to hear that--and that you took Cipro and had the reaction that you did. It seems pretty common that if you have a reaction to metronidazole, you might be more sensitive to a reaction to Cipro. I think it's because both drugs can cause mitochondrial dysfunction and/or tax the mitochondria that can lead to dysfunction. Metronidazole, in theory, does this by depleting thiamine, which needed for normal mitochondrial function, and Cipro, like other fluoroquinolones, has the ability to directly damage the mitochondria.

I don't think (but to be fair, don't really know) if the cancer is related. One in two people will get cancer; my mom's dealing with lung cancer right now and my dad just died from cancer last year. It's such a horrible disease and I'm so sorry you're going through that. I wish I had more suggestions or ideas about what to do or what the options are. The fact that nothing is showing up on scans is probably a good sign, I'd think, but what you're going through, along with metronidazole/Cipro reactions, is just too much.

I hope they can find a way to help you moving forward, not just "treat the symptoms." I do think a counselor (or family support) might be beneficial here; I saw a therapist over my metronidazole toxicity, not because I or the therapist thought it was "all in my head," but because I needed to talk to someone and get a more objective view of things. It did help.

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Re: BAH (# 1372)

Hi BAH, we here appear to be all suffering from serious antibiotic toxicity due to abnormal sensitivity or venerability. As I'm sure you have surfed the net looking for data, your doctors probably dismissed everything you have showed them. I'd bet that they even made fun of the literature despite the fact it may have been authored by a reputable scholar, or even from the the manufacturer directly. One neurologist dismissed my data claiming it was written by attorney's not medical doctors. I told hime it was written by Pfizer, the originators of Flagyl. Here see for yourself. https:/­/­jmp.sh/­Yb5QsVi

I'm suffering dearly, my life has been totally destroyed by Metronidazole 18 months ago... symptoms started out with the usual, balance disorder, ataxia, severe nausea, lightheadedness, blurry vision, but within 48 hours I went completely blind in my left eye, (it was my good 20/20 eye) then the headaches came and slowly progressed into severe debilitating migraines 24/7, followed by severe maddening ear tinnitus, and massive weight loss... (60 lbs in 12 days) I was so ill & weak I though death was at my front door. The doctors told me not to stop at the time, that it would all go away after I finished the bottle.

None of it went away, it only got worse with new progressive symptoms that have devastated my once peaceful life. They claim I must have suffered Metronidazole induced encephalopathy producing multiple ischemia strokes, massive retinal (Macular) damage due to abnormal inflammation damage, and massive destruction of my Vestibular system... all seen through MRI, and MRA, & CAT imaging.

Be careful. Stay away from this poison.

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Re: Dennis (# 1374)

If by "this poison" you mean this medication I'm totally in agreement. If by "this poison" you mean the American medical profession I'm beginning to come around on that too. LOL

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Re: BAH (# 1375)

Yes indeed, healthcare today is unfortunately a huge for-profit industrial business where huge quotas and deception rule. We are simply considered the vehicle for making money, nothing more... like herded cattle led to slaughter if conditions are right. There's a need for new legislation by State Licensing Boards to require all healthcare professions to take routine refresher courses in their field of practice every 3 years and then be retested or risk having their license revoked. Clearly doctors today are either too busy making the money or too lazy to keep up with the latest findings, safety warnings, drug alerts, diagnostic techniques, etc thus placing all their patients at greater risk for harm.

PS: Sorry for any previous typos, auto correct sometimes selects the wrong words. The word was "vulnerable" not "venerable" . : )

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It might be from the Ciprofloxacin. Google Cipro toxicity

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Chantal

There is no way to know for sure, each person is different. No doubt you have lasting effects and that's what brought you here, you feel somethings not right. You're not alone, that's why we are all here, looking for answers. Unfortunately it appears we're on our own as prescribing doctors refuse to acknowledge the latest medical data about this powerful antibiotic that easily crosses the blood/brain barrier. When it does it can wreak havoc on your organs. If you have a predisposition or are extremely sensitive to this drug, or suffer from an undetected brain or neurologic disorder, this antibiotic can exacerbate or worsen these conditions especially if the patient's kidney's or liver was already not fully up to par causing the drug to build up in the blood. These high serum level in the blood will rise quickly to toxic levels if not properly secreted during therapy. For some it takes months, even years to feel healthy again, while others never improve or get worse.

So I would report these lasting side effects to your doctor ASAP along with the FDA's MedWatch program. Please seek professional guidance from a third party if you do not feel as if you are getting any better. In the mean time, scan down this forum and read the posts from Erin or visit her blog for detox advive and other helpful information. https:/­/­metrogirlblog.wordpress.com/­treatment/­

Good luck

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Re: Karen b (# 1377)

Yes, that is what I suspect and or the flagyl or the combination....or..... I guess time will tell and I hope to be able to get through it.

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BAH (# 1378) --

Hello BAH, I also took metronidazole for H. Pylori. I only read the metronidazole insert after I took it for 11 days and saw a Warning: Metronidazole has been shown to cause cancer in mice and rats with long term use. At that point I was so upset to learn that I took a medication that can cause cancer. After I took this medication, I developed severe hormonal disbalance. I was having 3 menstrual cycles in one month. Doctors found 2 cysts and fast growing leiomyoma in my uterus. Luckily, cysts ruptured and went away but leiomyoma was still there at the last ultrasound. My gynecologist said that she doesn’t want to do any invasive procedure to destroy leiomyoma and monitoring it would be a better option. I just hope that it won’t become a big problem for me. Overall, It took me 9 months to get my menstual cycles back to normal and I hope it stays this way. BAH, I do believe that metronidazole is a pure poison and I hope that one day it will be revoked, so people won’t get damaged anymore. I just don’t understand how this drug is allowed to be practiced when it clearly destroys people’s health and lives. Please BAH hang in there and hope that everything is going to be okay! I hope that Lord will help us to overcome our struggles and continue our journey to recovery!!!

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