Lupin Lisinopril Pill Size Change (Page 4)
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I take 10 miligram Lupin tables - have been taking them 2x a day for 20 years. Today, I opened the bottle and they were 1/2 the size. Same markings on the pill and container, same color, same manufacturer but 1/2 the size. I asked the pharmacy assistant about it and she said the company was making them smaller but they were the same. I asked how they were doing that - were they removing fillers? Why did they have so many fillers in the first place. She said she didn't know, but would transfer me to the pharmacist. I asked the pharmacist and she sounded like she had been asked what the weather would be like the next day - "oh, I don't know...yeah...I don't really know." I don't feel comfortable taking these.

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REPORT

I have been on Lisinopril 20mg. for approx 3 years. I take 2 other medications also for high blood pressure. I have had no side effects with any of the meds and my doctor is very pleased with my reports. 2 weeks ago I picked up my new pres. for Lisinopril 20 mg. When I brought them home I had some of the old pills and thought the pharmacy had made a mistake. When I checked back with Walgreens, I was told that it was just a change in how they were made,and not to worry. I have been taking the smaller size for approx 2 weeks .It is the only change that I can figure out for the problems I have been having.I have dry mouth and I have a problem with taste. Also more frequent urination because I am always thirsty. My pressure is also lower than before which was never a problem. I will be seeing my doctor this week.

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That's after I started taking the smaller version that was just the same! Also my creatinine levels went from .81 to 1.2 in two weeks. Has to be the BP Meds only change I've made.

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It was Lupin. Been on it 15 yrs no problem. After a week I'm in an ER.

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Connie, what is the other generic BP Med you are taking?

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I was in it two weeks ended up in ER with BP numbers I've never came close to before. The did a cat scan too see if I'd had a stroke. I changed to another generic, and will see if it goes back to normal. My BP with meds is always 130/80. Always

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No, I haven't had a problem with blood pressure while switching from the larger 20mg pill to the smaller size. Everything is suppose to be the same except the inactive fillers have been removed. My pharmacist said it's mostly the inactive ingredients/fillers that cause a side effect with any pill. In April, I was put on a couple of new meds for a new cardiac issue and needed to make an adjustment in the timing of my different meds so there'd be no interference. I moved the Lisinopril to bedtime and it works out just fine. For those people who say they're experiencing various side effects from the smaller pill, whether "psychosomatic" (as another person posted) or not, it might be worth trying to move your Lisinopril to bedtime, as well. Please post if it works for you.

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I have taken the 10mg lisinopril for many years now. 2 months ago when I purchased the medication the size of the pill was smaller. I took the pills and noticed that my blood pressure was rising, This concerns me very much. Is anyone else having this problem. I'm going to go back to my Doctor to see if she has heard anything from others. I don't understand when they make a drug that no one is having issues with and then they change it with no way back.

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Loris and others,

There is no difference between the large pill and the small pill. I noticed the change and just wanted to make sure that the pharmacist did not give me the wrong pills which is why I saw these posts. All the manufacturer did was remove the inactive ingredients that made the pill larger. Inactive ingredients by definition have no impact on how you absorb the Lisonoril. The pill is dissolved within your stomach between 15 to 30 minutes regardless and the medicine enters your bloodstream in the exact same way. Lisinopril can cause dizziness regardless of the pill size. Also, as human beings we ALL (that includes me) are subject to psychosomatic reactions caused by the fear that the changed pill (for example) can cause us harm. A common misconception is that psychosomatic means "all in your head" but that is not true. The symptoms are real, but the cause of the symptoms is psychological (like the fear of the changed pill). This leads to a chain reaction of others saying that something must be wrong because "everyone else" is having problems. Again, a very human reacation that we are all susceptible to. And just so you realize that my intentions are to be helpful, I will give you a personal example. I fell and hit my head on the ice. About a month before, my brother in law had emergency surgery and almost died from a head injury that occurred months prior. I started to have headaches and thought the same was happening to me and I ended up getting an unnecessary CAT scan. After the doctor told me it all looked good, my psychsomatic headaches went away. Hope this helps someone.

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This is exactly what happened to me. I was on the old Lupin lisinopril for 6 years with a water pill and no issues whatsovever. Now, I'm on the new version of the Lupin lisinopril and extremely dizzy every day. Not feeling right at all. I had to stop the water pill because the lisinopril was enhancing the dizzi effect and making it so I couldn't even work. Now, I'm just on the 10mg new small version of Lupin linsinopril and extremely dizzy. It can't possibly be the same as it was before. I will be calling my doctor tomorrow to see if I can switch to the Watson (non-generic) 10 mg. lisinopril. My mother takes this one and has no issues at all. It' unfortunate that a manufacturer would change a pill and cause so many who are on it to have such severe dizziness and other side effects they never experienced before.

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Same problem as others.new size 10 mg.lightheaded .anxious.a little bit more tired.

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I started the smaller ones! My doctor said it would be fine. I've been nauseated, and dizzy every since. I'm calling tomorrow to see Doctor to make sure it's not something other then the drug. I also called FDA to file a complaint

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I haven't found anyone who carries Prinivil in longer only generic drugs. Most carry Leg Manufacturing which is who makes Lupin.

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Did you take your Lupin 20 mg. I've been having nausea every since I started taking them. Just wondered if you had problems?

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I've been taking lisinopril 20mg for years. Today I picked up a refill and the pills were a lot smaller. They are imprinted with 20mg on the front and lupin on the back. Should I take them?

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Follow up to my post above. This morning I called the Lupin complaint line (800-399-2561) and the rep went into a whole scripted scientific reason for the change in size on the 10, 20 and one other higher dose sizes. Seems they removed all the fillers, or inactive ingredients, and leaving only the active ingredients. As mentioned in my previous posting, my new 90 day prescription was filled yesterday and to my complete surprise, I received the original larger size Lisinopril that I had taken for years before the change. I brought the prescription back to Walgreens today and had a lengthy chat with my pharmacist. He has confirmed that Lupin has removed the fillers and will continue to manufacture the new smaller size for those doses. There are many warehouses that stock Lisinopril and here lies an answer to why I received the former larger size. The pharmaceutical warehouse that serves my local Walgreens continues to have the formerly large size in stock and it all depends on which batch my local pharmacy receives from a particular warehouse. My pharmacist checked his shelves for the 20mg and found both the large and small sizes. The pharmacist said most side effects come from the fillers, so since I was concerned about this, I decided to stay with the smaller size pill. The pharmacist was kind enough to replace my recently filled prescription with the smaller pills. I didn't want to take a chance. Hope this is helpful to Lisinopril users.

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I also take 20mg of Lisinopril at bedtime and noticed several refills ago that the size had gotten much smaller even though the pill said Lupin and 20. Pharmacist had no answer. Last night I called in a refill and tonight after getting home I noticed two changes...not only did my pharmacy strangely give me a brand new prescription # when I clearly had a refill left on my "old" number, but also, my Lupin 20mg were strangely back to their original bigger size!! I will be headed back to the pharmacy tomorrow to check this out. Something screwy is definitely going on with Lupin. Almost seems like a big time error in their manufacturing and now they're trying to correct. Too many people experiencing side effects with the change (or error) to a smaller Lisinopril 20mg. Has anyone else found their 20 now back to the original size?

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Prinivil and Zestril are the brand names for lisinopril. I also got a new Rx with new size and was concerned, I had a big problem with paroxetine by Lupin when it changed and found another brand. I went to CVS and paid more but they had 90 day supply of old Lupin lisinopril and I will watch posts online to decide what to do when it runs out.

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Prinivil is the brand name for lisinopril. There are others.

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I don't like the smaller version of the new Lisinopril tablet made by Lupin. What is the brand name for Lisinopril?

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I also take 10mg of Lisinopril - Lupin mfg - daily, and yes, I also noticed this month's supply was smaller. I called my pharmacy (Walgreens), and the pharmacist said I was the 2nd person this morning who called to ask about it, and all she knew was that the manufacturer has decided to make it smaller. That's all she knew unfortunately. But she said it should not affect the dosage. I also went on the Walgreens website and used their chat feature, and the representative there told me, "That is the correct description for the tablets. I have actually heard this same feedback from other patients about the medication, so it must be that the manufacturer has changed the way they made their tablets, possibly making them with less inactive ingredients. However, we have double-checked the imprint, so you can feel comfortable that is the correct medication." Maybe, someone just needs to go straight to the source - ie Lupin - to get the answer on why the smaller tablet size. Hope that helps!

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