Linzess Weight Gain (Page 4) (Top voted first)

I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain?

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Same ! I want to go off. This is killing me. I worked so hard to be in shape and all my arm and leg muscles are gone. Did you go off ? What did you take instead?

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I only took Linzess 2 times and I have not lost the bloat or weight gain yet and it's been 1 week since off of it. My stomach is more distended than the other day. What do you think happens with this drug?

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Yes weight gain I think for sure and bloating maybe 5 lbs weight gain

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YES!!!!
I gained 15 pounds on this medication and only took it for 2 weeks. I am playing hell now trying to kick the weight off!

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Linzess makes you retain water to help flush out your body. I had could barely even get off the potty 24/7, and in the meantime still gained 15 pounds in the 2 weeks I took the medication.

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I certainl would love to know what it is about that drug that makes us gain weight that won't come off!!!!! This is a REAL problem for me!
Thanks for you input!

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Am in the same boat! I lost all the wright after both pregnancies but can't seem to kick this Linzess weight. Have you found anything that works??

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I also was on Linzess for about 6 months. I was so bloated and swollen that if I wasn't too old to be pregnant people would probably think I was pregnant. I gained 30 lbs and have been off Linzess for about 1 year. I still gain weight and look pregnant. I take Zumba classes 3 times a week and two days a week I do the treadmill or eliptical 30 minutes and a muscle toning DVD for 30 minutes. I keep a food log and stay between 1200 to 1300 calories per day. I also keep track of carbs and fat per day. I got tired of donating money to weight watchers so I quit, it wasn't helping me. I am very depressed and discouraged that I cannot lose the weight I gained on Linzess.

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I've gained 20lbs in last 4mo. I too look like I'm pregnant.

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All I can say for sure since starting Linzess is that I am constantly hungry. I have room to spare to maintain a healthy BMI, but this feeling of always being hungry, and never being satisfied, is making me crazy. Yesterday I cut up two cantaloupes so that I would have fruit handy, today I ate two cantaloupes in one sitting! The worst part is, is that even after maintaining a diary of everything I have eaten and every BM I have had for 3 weeks I can't tell if I am any better or not. The results are not consistent. I may just go back to being a slave to my bowels.

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Re: DIK (# 32)

EXACTLY! Me, too. See my post from today, 9/7/17. That is it. I'm done.

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Re: Newman (# 59)

I've been doing a lot of research on this issue since my sister is having the same problem. I came across something called Trulance that just came out in January that everyone is saying is way better than Linzess. I can't say for certain whether or not it's better since I haven't taken it but I think it would be worth looking into based on what I've read. Hope this helps!

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Re: Will (# 75)

I think I will look into it. I appreciate the information.

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Since I have been on Linzess, I Find that I have to pass gas all the time.Is that natural?
After I take the pill in the morning,I have at least 2 Bowel movement, if I don't take a pill for the diarrhea, I will continue to have BM,'s,at least 2 more times during the day.

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Re: dbrentlinger44 (# 61)

I also gained 30lbs while on this medication, although I was on it for approx. 3 years or so. I took myself off of Linzess about 3 months ago and not only can I not lose weight, but I've gained 10lbs since then. Would you mind an update? Have you had any luck losing the weight since?

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Re: Melinda (# 2)

I've lost 15 lbs taking Linzess and Dexilent. No complaints here. Finally at my high school weight. Feel awesome. New diet and high fiber intake are weight loss extreme because you shouldn't eat anything bad for you.

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When does the feeling of being extremely hungry go away..ive been on Linzess for 5 days and feel like I am starving.. I eat a healthy diet and watch my weight because I had stage 3 breast cancer 12 years ago.. I am 68 years old and weigh 131 lbs.. I have some diarrhea, but it is tolerable.. Feel weak and shaky too..

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I have had IBS for 8 years --> Linzess makes symptoms much milder...especially when I drink extra liquids.
__ Been taking 290mcg/Linzess for 6 months: gas + some boating. 1st few months weight gained 5 lbs. Now I've lost weight: down 10 lbs. (I don't care much about the weight: I'm a 74 yr old woman w/ Fibromyalgia.)
__Having less IBS is very important to me. I'm very grateful, eventho Linzess works on and off. ---> Maybe because I didn't eat in ½ hr after taking Rx. Today I am eating a snack. Maybe Linzess can work daily if do I eat every morning. Will try that - (tho not hungry in mornings.).
When I don't go for 3 days the pain after BM can be intense.

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Hi there. I have suffered from Ibs for years. I lived on laxatives and enemas and I am a healthy eater but constipation rules my life. I started on linzess in 2015, which worked, but became too strong for everyday use, causing watery diarrhea and black stool. Now I only dose twice a week but now have high blood pressure which the FDA now reports and weight gain. I am stopping this and pray I can go back on regular laxatives. The high blood pressure is not worth it.

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Re: MarciaOR (# 85)

Hi, I want to add to my previous comment that I gain approximately 13 pounds.

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I take thyroid meds and Migraine Meds....How do I ensure that the Linzess isn't "getting rid of" these meds ...

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Type 1 diabetic, hypothyroidism, high blood pressure, allergies, glaucoma and constipation. What else? Taking Linzess. D...

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I am the same. I have lost 85 lbs over the last 1 year. I have gastroparesis. After 120 days on linzess I am up 15 lbs. ...

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how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss,...

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Hi! My Dr. Gave me linzess to help with weight loss. HOWEVER, I am reading all the posts about horrible weight gain, I a...

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I eat very clean, rarely at restaurants. I have been on Linzess (Lazy bowels) for years, been on synthroid (subclinical ...

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I have been on linzess for 2 months. I have lost 8 pounds (last time I checked). I'm a heavy female. Suffered with c...

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I have been on 50 mcg of levothyroxine for 5 months and I have gained 15 pounds. My doctor tells me that it should be th...

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hi I am 31 years old with skinny body.my weight is just 34kg.I looks like athopian child whose arms and body is lean.I w...

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Ruchi here.i want to put put on weight currently my weight is only 43 kg. and want to put on up to 50 kg so help me is p...

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