Linzess Weight Gain (Page 3) (Top voted first)

I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain?

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Same here! Gained so much weight so I took it upon myself to stop taking them... Having such a hard to lose the weight and the bloating. I regret taking this pills... So freaking swollen!

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Oh thank god it's not just me!!!! I just lost 105, and I'm freezing out. Look like the Pilsbury Doughboys mistress!!! It's not really helping me at all, been 3 weeks and still not on a normal cycle!

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I have been taking Linzess for OID for about 4 months now. I am quite active and am a senior citizen. Didn't attribute my weight gain to the drug at first but have gone from 142 to 156 in that time. No other changes to diet. Pretty convinced this drug is the reason. Taking the 290c dose and really must start looking for an alternative rather than a new wardrobe. Bloating is evident and still not consistent with elimination.

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Since I have been taken Linzess for constipation I have notice that I have a lot of bloating and gas rumbling in my stomach I am so disappointed with this medication it helps me in one way but hurts me in another way.

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My question is can I drink my coffee right after taking lizness

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Can I take 2 linezz in a day. One is not working for me. I can't handle this bloating feeling daily

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So did you loose 20 pounds on Linzess or did you gain 20 pounds on Linzess? I'm supposed to start taking Linzess tomorrow so please help me understand if you lost and are angry or gained and unhappy. Thank you!!!!

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I have been on Linzess for about a year. I have gained so much weight!! I have gone up two sizes larger. I am hungry all the time and I can't seem to be satisfied after I eat a meal. I am so miserable.

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I too gained about 20lbs...in 6 months! Never knew about the weight gain side effect until I googled it after NOT being able to fit into clothes from a yr ago. I noticed I gained weight but just a little in the beginning, but then as time went on I was gaining more and didn't realize it until just recent! Not happy! I stopped the med about a week ago! I look 7 months pregnant...clothes do not fit and I still have cramps, bloating, gas, etc. Never taking this medication again.

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I've been on Linzess for about 6 weeks. While I truly appreciate that I can finally have a regular bm, I hate that I've gained almost 20 lbs. and that my sugar has been running high

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I do not weigh myself and I haven't in 5 years, so while I feel as though I'm gaining weight and feel puffy... When I went to my doctor to talk about this, he weighed me and told me I weighed the same as the first time I met him (pre ALL medications). That being said, he prescribed me Amateza... And for the first 2 days of that stuff, I felt amazing (minus a crazy headache), but then things went south... ESPECIALLY my mood! I got really depressed, crying for NO REASON- I mean, I had a FLAT FLAT STOMACH, why would I cry about that? And you know what? The second I stopped taking it, BAM, my mood was happy as a clam again! It's crazy how these drugs can truly affect EVERYTHING. I've been taking Linzess again for the past 2 days and I am able to have BMs... We shall see what happens in terms of weight. I am starting to feel a little all around puffy again though.

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I'm on WW too and just started Linzess this week. I'm worried about all of the reports of weight gain and since I am diligent about my points and rarely touch my weeklies, know it is not my food intake. I have only gained one pound so far but am still concerned. I've worked so hard and am almost at my 10%!

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Yes I have been on this site for about 3 weeks and I gained 15 pounds and I don't eat much. I'm not taking this medicine anymore.

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Thank you all so much.. I recently started a new gym and boot camp x3 a week... doing great eating clean up my exercise and weights everything after 1 Month my weight went up ( as did my body fat%) which should of went down... beacause I am now eating more protein and fewer carbs... so today weighed in for our 21 day challenge and I'm up 4 more pounds and body fat went up again... so by this time I'm in tears, the coaches and I go over my food diaries, water in takes everything.. I get home BAM...... Started on Linzess end of September... Not worth it! Stopping today. I did notice a BM regularly, for first week or so, but my stomach would be bloated.. but I don't understand if you go to the bathroom and so much is coming out.. several times a day.. How are you gaining weight????

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I also started linzess a week ago. First week I had explosive diarrhea, and this week its more soft. Today I tried to put on the exact same jeans I wore exactly 1-week prior(with thermal pants under them), and i struggled to get them on with no extra layers under them. Dont know if I even want to continue the medication anymore. Im on adderall so my appetite is the same, so Im not sure how you gain weight on medication that helps you with discarding waste.....

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Yes I did gain a lot of weight and even after getting off it I'm still gaining weight. It helped me a lot I thought and I went several times a day everyday probably too many times a day. But then I had to have a hysterectomy bc of my iron levels and was having issues after my hysterectomy. They decided to do a ultrasound bc of the issues I was having and the lady that was doing my ultrasound asked me if I had been having bowel movements and on that day before my ultrasound I probably had at least 6 bm and she told me the reason she was asking is bc I was completely full of stool. And then 8 weeks later after my hysterectomy I had to have a total hemmoriodemy and I was still taking Linzess 290 mg everyday through both surgeries like instructed by my doctor. The reason for the hemorrhoidectomy was from straining so much before Linzess on the years. After all healing from both surgeries and I was still taking Linzess everyday at a dosage of 290 mg I started noticing my stomach remaining swollen. It was extremely bad even after having 10 to 15 bowel movements daily. Now today no matter how many bowel movements with a laxative i never feel empty. I have stopped taking Linzess for over 2 months now. I look like i'm still 6 months pregnant and still gaining weight. So today i've been off Linzess for 2 months and am still having issues. I will always believe my issues come from using Linzess 290 mg everyday. Bc I shouldn't have been full on that ultrasound and I think with my bowels just sitting inside me caused some type of infection. After my 3 antibiotics I finished yesterday I'm still passing infection and blood and so much bloating I feel horrible. I'm not sure if I will ever feel good again or if they will ever find out what is wrong, causing me to pass blood and infection. Bc they sent off 4 stool samples and nothing came back. And I took my last two antibiotics yesterday and still passing infection and blood and bloated so bad my stomach hurts so bad and I'm not sure what to do. I hope this will help someone and if you had these issues please reply.

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I've been taking it for about 2 months and not regularly since i work a retail.schedule. I've been gaining weight.I'm not eating more then i usually do. The weight gain really upsets me. I can see if i was over eating or something. Then i decided to check and now I've found others are having the same problem. The only thing linzess had done is give me bad diarrhea. I got better results taking miralax without the weight gain.

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I have being on linzess for about 5 years and I have gained weight my stomach is so big that I look like I am pregnant. I have mentioned to my doctor about my weight and my stomach and she tells me to keep taking probiotics. After reading all the comments I am going to stop taking linzess.

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Same for me. Started Linzess last May 2016 gained 20 lbs by the end of June. By Sept added another 4 extra lbs. It's been 10 months & I am unable to loss any weight. I have no appetite, eat very little. This has never happened to me before. I've worn size 2-4 forever. And now I have had to buy new clothes because nothing fits. Had I known about possible weight gain, I would have never taken it. But I was desperate for relief of constipation. Now I'm bloated & fat & still severely constipated.

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Same here ! I thought I was crazy my trainers have no clue how I'm gaining and I am a Tiny tiny frame ! I feel horrible swollen. 5 - 7 lbs. I'm going insane have you stopped the medication ? What did you take instead ? I'm stopping asap I'm so upset

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I take thyroid meds and Migraine Meds....How do I ensure that the Linzess isn't "getting rid of" these meds ...

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Type 1 diabetic, hypothyroidism, high blood pressure, allergies, glaucoma and constipation. What else? Taking Linzess. D...

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I am the same. I have lost 85 lbs over the last 1 year. I have gastroparesis. After 120 days on linzess I am up 15 lbs. ...

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how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss,...

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Hi! My Dr. Gave me linzess to help with weight loss. HOWEVER, I am reading all the posts about horrible weight gain, I a...

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I eat very clean, rarely at restaurants. I have been on Linzess (Lazy bowels) for years, been on synthroid (subclinical ...

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I have been on linzess for 2 months. I have lost 8 pounds (last time I checked). I'm a heavy female. Suffered with c...

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I have been on 50 mcg of levothyroxine for 5 months and I have gained 15 pounds. My doctor tells me that it should be th...

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hi I am 31 years old with skinny body.my weight is just 34kg.I looks like athopian child whose arms and body is lean.I w...

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Ruchi here.i want to put put on weight currently my weight is only 43 kg. and want to put on up to 50 kg so help me is p...

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