Linzess Stopped Working (Page 2)

I have been on the 145 dose of Linzess for several years now, and it was like a miracle drug. No side effects, and for the first time in 30 years, regular BMs. The past few months have not been so great, though. Constipation, bloating and cramps have returned. I saw my Gastro a few weeks ago, and she upped my dosage to the 290. No change. Has anyone else experienced anything similar? So frustrating!

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I have been taking linzess for about a year. first on 125 mcg and after a few months 290 mcg.I now have not had a bm in 5 days curious.. what is smooth smooth tea?

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Thank you! I'm in the same boat with y'all, will give this a try. Sure would be cheaper than the Linzess!

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I was on Linzess 290 for years and it worked well. Had to take it at 1 AM so I could wake up and go. Had to stop 6 months ago because it got too costly. Took laxatives and stool softeners and teas. They stopped. I just started some other meds that cause more constipation-great. So I'm going back on Linzess despite the cost. I hope it still works.

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I have also been taking Linzess for 5 months now because I was diagnosed with IBS-C. For the first week of taking a Linzess i felt relief 2 hours after. Since then I've been bloated and constipated. I feel terrible. I took Linzess 290mg. NO RELIEF.

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I've had chronic idiopathic constipation for 10 years. I just started the 290mg. Linzess 2 days ago and so far nothing but bloating. Is it fair to say this med will not work for me at this point? I did follow the directions appropriately.

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I was on linzess the highest dose it worked for about a month My doctor told me to take 2 Ducolax every two days if no BM yes that worked until I was down to 89 pds from ducolax cleaning me out ! I stopped linzess and I am going back to my Gastro and asking for a better way Linzess is garbage and I was getting bad sinus infections from it when I stopped my sinuses got better !! There has to be a better way then these docs pushing laxatives on Us ruining our gut in fact if you read on here people who say it works there taking something else with it . From anyone I talk to they say it just stops working after awhile To everyone good luck Zelnorm was the only thing that worked and they pulled it off !!

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I have been on 290 and now it's not working, I've been on it for 8 months. Sometimes it would take 3-4 days before it worked. But it's been a week and not doing what it use too.Has anyone else had that happen. Now I feel so bloated I don't know what to take.sue

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Re: Andrea (# 20)

Andrea,

I have also started taking my linzess 290 with a laxative in the am. As many have stated, my prescription on linzess started off great (Id rather be wed to the toilet going, then constipated and in pain) but after a year, its efficacy has stopped working. I feel hopelessly devoted to laxatives again. Sometimes the otc laxative works in combo with the linzess but this is unpredictable. Does anyone find that switching to dosing in the evening much better or increasing the dose to twice daily better than adding an otc laxative? Any suggestions would be appreciated. I have been slowely becoming more crippled by the chronic pain of ibs more than ever recently. i work in surgery- i am 33 - and extremely health conscious, but there are days that i am in so much pain now that i cannot stand and operate all day anymore. I fear that the disease has become a true threat to my career and livelihood

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Same here have been taking it for 3 months the way i am suppose to take it and it just stop working call my Doctor told me to continue taking it nothing change He told me he has nothing else to give me that's crazy

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YES! I've been taking linzess with 5 sennakot and stool softeners,it would work with diareah of course,but after 5 weeks it just quit.Left me with incredible gas,cramps and bloat. This drug is a nightmare.I don't know how I'll make it through the day.I've been diagnosed with redundant sigmoid and CIC. I'm in big trouble because I must wiork in misery

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I have been on the 290 mg for 18 months and it was great to clean me out ; unfortunately , it would take 6 hours or more to work . And also I had to make 3 - 5 trips to the bathroom to finish and I always have watery bowels with the 290 . But , it fells GREAT when It's over !!

Now ,being a 81 year old retired mechanical engineer , the 290 just STOPPED DEAD working 6 days ago . Today my bowels finely worked nd was loose ,; but , not diarrea

I have an appointment with my doctor in 2 days to get checked out because the 290 stopes and to tell him that I believe that I need another Colonoscope because of some sharp pain in my colon sometimes and all of the bubbling in my colon plus I had Colitis 11 years ago and lost almost 50 pounds because of the colon infection !

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YES! I bumped up to the 290 dosage and it’s no longer working.

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