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Klonopin And Tolerance

Updated October 12, 2012
Jane Goodall and her Gombe chimpanzees Says:
Wed, October 10, 2012

Are there substances one may take to increase the amount of time before one develops tolerance to the anxiolytic effects of klonopin?

I am currently on a 1 mg 3 x daily, and my psyc suggested going done to 1 or 2 on some days to help avoid tolerance. I know some folks are fortunate that they never seem to develop tolerance to the anxiolytic effects, and no strong scientific evidence exists that I have seen that indicates it will happen. Still, anecdotal reports of such abound.

I have heard the magnesium glycinate and Coenzyme Q10 may help prevent tolerance, but I have found no research to that end, only anecdotal reports. Does anyone have any links to evidence about these or other substances that may stave off possible tolerance to the anxiolytic effects of klonopin?

Your help will be greatly appreciated.

1 Reply

1
Verwon Says:
Fri, October 12, 2012

No, there are no substances that will do it, as far as I know.

However, altering the dosage as your doctor suggested can help prevent it, as well as taking a medication "holiday', which is what some doctors have their patients do. They may have them take a break for anywhere from a few days to a few months. Sometimes with no medications, at all, after tapering down, or sometimes they may have them use a different medication.

Learn more Klonopin details here.

Does anyone else have any ideas?

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