Inactive Ingredients Of Qualitest Or Leading Pharma Lorazepam (Page 2)
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What are the inactive ingredients of Qualitest lorazepam or Leading Pharma lorazepam? Does anybody know?

It seems that its formula might have been changed because I feel 1mg is less effect than before or does not work. I used to take Ativan 1mg before abroad and one month from Kaiser in the U.S. but they gave me refill as generic lorazepam (Qualitest). I felt 50-60% effectiveness compared to Ativan(brand lorazepam). I can't take Watson lorazepam as it does not work for me causing side effects (rapid heart beats, sweating, anxiety, dehydration). Qualitest has less side effect (less dehydrated than Ativan) I did not have physical dependence on Ativan for long time and quit too. But this generic lorazepam is getting less effective over a few months.

Also my pharmacy had changed Qualitest to Leading Pharma without notice so I had to get new transcript for new pharmacy for qualitest (I transferred once).

I did not take it for mental problem (anxiety or panic attach) but for side effect of levothyroxine (I should take it as I got my thyroid gland removed). Ativan has calming effect and reduces heart beats, sweating, and stiffness and helps sleeping a little as I suffer from some pains. It does not fix my problem but reduces temporarily. Zanax does not work. Cymbalta does not work. All depression medicine does not work. With Cymbalta, I became unconscious and was hospitalized. I almost died taking Prozac due to side effects and worsened my symptoms. Ativan only helps a little.

I called most pharmacies in LA but many of them sell Leading Pharma lorazepam and some sell Watson. Most pharmacies do not receive return once it is opened (only one pill is taken) while Rite Aid does and during the period of medication, patients can't buy another lorazepam even with new prescription so if the medicine cause side effects or does not work, customer have to wait until refill period comes.

I found only one pharmacy selling Qualitest lorazepam but most others sell Leading Pharma, I don't know why but maybe because of their marketing. So I may change to Leading Pharma but am worried that it does not work like Watson.

I wonder if anybody tried Leading lorazepam and if it works, though effects are different according to each individual. Ativan in the U.S. is very expensive ($2600 for 1mg 30 tablet) and most doctors do not prescribe it and insurance is mostly not covered or do not want to pay for it. That's why Kaiser gave me brand Ativan only once and changed it to generic.

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Leading works great. It’s not like Mylan but better than the other placebos. Yet to try Teva. Would like to hear if someone can compare the two

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Re: Hnnypooh (# 91)

I went through the same. Ended up in ER with severe panic attack with very high heart rate..

Go back to thread maybe 6 months ago. Leading Pharma does not work for me..their pills are a little large for sublingual???

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Re: David (# 2)

Yes the potassium in the leading brand lorazepam is a tablet disintegrate meaning you will get the most out of the pill if taken sublingually instead of oral I put one under my tongue in about 20 seconds it's dissolved and I don't swallow for about 3 minutes and I feel immediate relief I'm starting to wonder if this tablet is only supposed to be used sublingually hope this helps

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Re: Charlii77 (# 90)

Hi , I tried taking for 3 weeks . I had severe anxiety . Very strange physical symptoms . Felt like I was going through withdrawals . Nausea , headache . Multiple things . Once I took 1 ativan it was so much better .

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Re: Hnnypooh (# 88)

How long were you taking the LEADING PHARMA LORAZEPAM and what were your symptoms

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Yes I'm on leading lorazepam it taste like sugar because of the potassium it has an inactive ingredient these comments and side effects of this brand of pill causing all these death side effects are just ridiculous give them a try all the generic lorazepam are the same to me good luck

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Re: Paul (# 79)

I was made to take them after I started having horrible panic attacks . I went off three weeks later had another panic attack within a week . Went to ER was told by them and my Dr I had to stay on them prob for the rest of my life . I was upset but found over time I took smaller doses and spread them out . That’s what my dr suggested and it has worked in that regards .
Now years later I get griped at for taking them by many .. it’s like I did not make the decision to stay on them they did . So here I am . Yes I have had to increase them about every 8 years . However when I went to the brand Ativan I actually was able to decrease the meds . They are the actual correct dosage . Not full of garbage fillers . Teva worked the best for me besides the brand name . Watson made my jaw hurt . Leading brand was the worst I have ever taken . Like taking zilch .

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Re: Deedee (# 21)

Wow that's interesting you were on leading lorazepam for a month and it took that long to realize they didn't work and you have severe panic attacks hmm I've been on lorazepam for 26 years and I take leading brand 2mg for severe panic and ptsd and I'm not being rude but lets be real here if in fact leading brand did not take your panic away and did not have the ingredients to treat it and you have taken it for quite some time im sorry to say but you would have ended up in the er for withdraw and possibly seizures after a day or two

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Re: Charlii77 (# 80)

I think that every pill should work the same. We should not be put through tests. They should all be required to use the same amount of active ingredients. It’s not fair that people such as myself should have to be sick and going through withdrawal symptoms because we are treated like guinea pigs. If you needed a heart pill and one didn’t work properly would you continue to take it?? People can have seizures etc not having the proper dose. I was able to be put on the brand name Ativan and have my insurance cover it. Thank God! Guess what? I actually take less than I did on generics.

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Re: Charlii77 (# 84)

No doubt different manufacturers work for different people. Watson hasn’t been made by Watson since bought out by Teva (Actavis is owned by Teva) in 2013. The tablets still say Watson but that’s because they are still using the same molds......i’ve Been on benzodiazepines for 51 years- lorazepam specifically for 7-8 years. Watson in 2012 was virtually identical to brand name Ativan ...I couldn’t tell them apart for effectiveness. Once the India-made Teva lorazepam withthe Watson imprint came to market there was definitely a difference in color (it is whiter and shiny compared to the old Watson) and more importantly-effectiveness. I thought it was just as good too....until about 6 months later I thought it was my anxiety increasing. Just yesterday I spoke with my medical manager who acknowledged that many of his lorazepam taking patients were saying the same thing.......it’s not our imaginations.......I wish it was. If what you are currently taking works for you.....that’s great......

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Re: Richard (# 83)

I have svt and I'm also on heart medication and the 2mg lorazepam from LEADING PHARMA been on them for over a month no problems I personally think Watson brand is the best also keep in mind I've noticed these comments are from last year has any one gotten an up date who knows maybe they are being made better as of now I hear so much about how these pills taste like sugar they do not taste like sugar they taste exactly like the inactive ingredient prcillin potassium

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Re: Charlii77 (# 82)

When I first joined this discussion I disagreed with everything negative said against Leading and Actavis....well..after being on them for a year.....I have no problems admitting I was wrong...several months ago I started having tachycardia during the day with any slight exertions..up to 171 bpm...and at night waking me up 3-4 times a night with lower high heart rates until recently they went over 150.....not good. Literally just came back from docs .....I barely got the words Actavis’ “Watson” is not like the old Watson...it’s not as effective and neither is Leading..out of my mouth ...when he interrupted me to say he has heard this from many many patients in the last 3 months.....so he wrote me a script of a light dose of a benzo w/ a longer half life to take at night...along with the Actavis Lorazepam. .05 mg of Klonopin. It’s a shame American manufacturers have sold out their patients so they can make higher profits.... ALL Lorazepam is now made in India ... Thus they do not, by law, have to adhere to the "no less than 5% variation" in the active ingredient FDA law... As an import they can vary 5-20%.

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Re: Hnnypooh (# 81)

I totally agree I mean ive been on lorazepam 26 years and yes I'll be the first to agree some makers are better than others but these lorazepam made by LEADING PHARMA are not the best but they do work is what I'm getting at here

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Re: Charlii77 (# 80)

Hello, I am happy to hear that it’s working for you . Many people have not been as fortunate as you are. I actually had a lot of issues when I was forced to change brands. No longer making brands that worked. I gave plenty of time and I was miserable. I ended up on brand name and take less of it then a generic. They are full of fillers, brand is not. So I think people were having major issues. They were wanting to know, and if they are having problems then it should be addressed.

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Re: Richard (# 14)

Yes the leading brand lorazepam 2mg works it's sad seeing all these reviews where people believe this pill is garbage this company was awarded 40 million dollars to continue manufacturing they are definitely in it for quality and business and this pill does not taste like sugar it tastes sweet but all other brands of generic lorazepam have tasted sweeter it of course your body knows what is needed to feel well and with generic pills they are made differently and people either got the feeling of relief or aren't satisfied and go elsewhere but the saddest thing here is all these bad reviews I believe people are just agreeing to get their liking and their making of the generic pill there bodies are used to and that's not right

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Penso que os benzodiazepínicos,incluindo o Lorazepam,são realmente bastante eficazes,no tratamento da ansiedade,mas não há como negar o seu grande potencial de dependência psicológica,ao menos psicológica.O problema desta classe de medicamento 'benzos',que também promovem um relaxamento neuromuscular,que facilitam a indução do sono,mesmo os que não pertencem à classe dos indutores do sono,que são de curtíssima duração,é ,a meu ver,que após alguns anos de uso contínuo,mesmo em baixas dosagens,podem,além de desenvolver a tolerância 'aumento da dose',para o mesmo efeito,acontece com certa frequência,a necessidade de se adequar as dosagens;nem sempre para um aumento de dosagem,mas também aos horários;quanto menor a dosagem eficaz,melhor;se tomamos 1 mg de alprazolam ou lorazepam,por exemplo,e sentimos o alívio dos sintomas,melhor é procurar manter ao máximo,com esta dosagem;uma simples miligrama a mais,podem nos deixar muito desatentos,letárgicos,e 'sem emoções',principalmente à longo prazo,o que não é nada saudável;as vezes é preciso combinar com algum antidepressivo,que possua efeitos ansiolíticos,como a sertralina,fluoxetina,dentre outros,assim como em certas situações,inserir o uso de algum psicoestimulante leve,como a ritalina,modafinila,pemolina magnésica,dentre outros não deve serem completamente descartados ou desconsiderados;ao menos podem eventualmente diminuírem as sequelas cognitivas reversíveis,assim como serem úteis,no 'desmame' diminuição gradativa do fármaco benzodiazepínico..

Google Translate (may not be 100% accurate):

I think benzodiazepines, including Lorazepam, are actually quite effective in treating anxiety, but there is no denying their great potential for psychological, at least psychological, dependence. The problem with this class of 'benzos' drug, which also neuromuscular relaxation, which facilitate the induction of sleep, even those that do not belong to the class of sleep inducers, which are of very short duration, is, in my view, that after some years of continuous use, even at low dosages, they can, in addition, to increase dose tolerance, for the same effect, the need to adjust the dosages, not always for an increase in dosage, but also for the times, the lower the effective dosage, the better; we take 1 mg of alprazolam or lorazepam, for example, and we feel the relief of the symptoms, it is better to try to keep to the maximum, with this dosage, a simple milligram more, can make us very inattentive, lethargic, and without emotion s, mainly in the long term, which is not at all healthy, sometimes it is necessary to combine with some antidepressant, which has anxiolytic effects, such as sertraline, fluoxetine, among others, as well as in certain situations, insert the use of some psychostimulant such as ritalin, modafinil, magnesium pemoline, among others should not be completely discarded or disregarded, at least may eventually reduce the reversible cognitive sequelae, as well as being useful in 'weaning' gradual decrease of the benzodiazepine drug ..

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Re: Richard (# 77)

Please contact the FDA: https:/­/­www.fda.gov/­ForConsumers/­ConsumerUpdates/­ucm095859.htm

I did over my meds not working. Same manufacturers. People need to get the word out!

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Re: Cynthia (# 76)

Well, the good take from this rapid reaction is your reaction was more likely psychosomatic.... absolutely real but produced by your body not by the meds... I only wish Lorazepam (made by anyone) worked that fast..... fastest I ever had it work was 20 minutes and that's putting it under my tongue that hastens it a bit...lol...no wait... insomnia in 5 minutes? You must mean the first day, not 5 minutes literally... even so, that's REALLY FAST ... it takes the body/mind a little while to realize things aren’t the same......but I think for what’s available now-Leading and Actavis......I think they are pretty much equal....both poor.....it took a while for the 'old' Watson to get out of my system.....I'm done with Leading, but Actavis is no better...I asked the pharmacist...what happens if Actavis stops making it? (Costco won't deal with Leading because Actavis is offering cheaper deals).... He said there are several companies waiting in the wings for FDA approval to start marketing it. Whether that's true or going to happen, I haven't a clue...but if it's true I hope they are aware how dissatisfied we are with the two current products.

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Re: Richard (# 20)

Pharmacy changed manufacturer from Sandoz to Leading Lorazepam. Within five minutes I reacted to it badly. Twitching, nervousness, diarrhea, itching, insomnia. Never had a problem with Sandoz or Watson.

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Richard (# 70) --

Yup that's the lady. Showed some of her YouTube videos to one of my docs years ago ---She was anti benzo freak. Thought all the new SSRI's & SNRI's were the next best thing to Murphy's Oil. Ended up with a permanent ring finger twitch from Effexor. I'd already been through the old skool antidepressants that made a basket case out if me back in the early 80's. You have no idea how important it is to keep your medical jacket. (Well at least some don't)

As for Valium you couldn't get me to take that stuff even if it was free. The half life and a short time effects of its usage is worst then Ativan. I only took Valium when I was on a dusty island with a 40 mile perimeter, water on one side and mountains on the other. Ativan was just making the scene about that time. Was loaded up on Tofranil and Amitriptyline. The 3 bar shoulder board thought that was a great combination for panic disorders. That gave me a racing heart of 134 and hallucinations. ;) Oh yeah he put me back out on the line turning multi-million dollar equipment.

But back to Valium I only took it as needed thankfully. Yes I realize that Valium was the happening drug at one time. Actually Miltown was a lot more popular in the timeframe you spoke of. My aunt was on that junk. Turned her into something horrible.

Yes the folks that make these pills we're on knew just how addictive they were before they hit the open market. But the question is what else would they have given folks that were debilitated from panic disorder. I suppose there might be a magic bullet we don't know about that works? Dunno...

Lorazepam works just great as long as they stop changing the formulas. Then they do what they should do for many. As we've all said out here one might not work for one while another may work for someone else. So far I've only had two work efficiently.

As for many we are shunned for being on what were on only because the new drugs are the real McCoy according to many pdoc's. The sad thing is that isn't all true for everyone. You see if those drugs worked trust me when I say this I'd be on them. All my trials and errors were performed under close monitoring. Ok enough of the past. I'm in hopes this Sandoz will balance out for me long enough to start back to my beginning. But as of now it's got me a bit unhinged. This too shall pass.

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